A young teenage girl, Zoe Benson, accidentally kills her boyfriend with a genetic affliction that traces all the way back to the witches of the Salem witch trial. Zoe is taken against her will to a girl's school in New Orleans where she and others are to be trained in their gifts. However, the headmistress' mother, the Supreme, is seeking a way to maintain her youth and will go to any lengths to do so.
When Zoe cracks from the pressure, Fiona steps in to keep the local law authorities from connecting her and Madison to the bus incident. Meanwhile, Cordelia seeks a way to become pregnant, Delphine escapes the school, and Fiona meets with Marie.
Zoe tries to reunite the resurrected Kyle with his mother, but things don't go according to plan. Meanwhile, Fiona takes Madison under her wing when the Supreme learns that the girl is her successor, and Madison and Nan visit the new next-door neighbors.
On Halloween, Marie prepares to make the next attack in her war against the Coven, and the Council visits the school to investigate the disappearance of Madison, Fiona's successor. Meanwhile, Zoe tries to get through to a resurrected Kyle, and Hank gets up to no good while he's out of town.
To save her schoolmates, Zoe takes command and discovers a new power. Meanwhile, Fiona deals with the aftermath of the acid attack on Cordelia and exposes the person responsible to the Council.
Songs: Dr. John
-- Right Place Wrong Time
When the girls try to contact Madison's spirit, they inadvertently communicate with the ghost of a serial killer from New Orleans circa 1919. Meanwhile, Cordelia learns more of the secrets thanks to her new gift of The Sight, and Marie meets with her secret ally within the school.
While Zoe works out sleeping arrangements with her two undead roommates, Delphine and Queenie bond over fast food, and the Axeman and Fiona bond over a shared past.
Misty arrives at the school with a resurrected Myrtle, and Cordelia recruits them to help her in her attempt to dethrone Fiona and appoint a new Supreme. Meanwhile, Marie continues torturing Delphine, and someone takes a shot at the Ramseys.
Fiona tries to form an alliance with Marie against the witch hunters, while Nan puts Joan in touch with her comatose son. Meanwhile, Madame Delphine gets a lesson in racial sensitivity.
Songs: Stevie Nicks
-- Kind of Woman, Odetta
-- Oh, Freedom, (Unknown artist)
-- Just a Closer Walk With Thee
Fiona brings in Stevie Nicks in order to lull the leading Supreme suspect into a false sense of security. Meanwhile, the Coven learns the truth about Hank and the Delphi Trust with some help from their new ally, Marie, and Nan learns what happened to her boyfriend Luke.
Fiona and Marie get a surprise at Nan's funeral when an unexpected visitor arrives. Meanwhile, Myrtle helps Zoe to escape the school, and Cordelia makes the ultimate sacrifice to save the school and her students.
Queenie attempts to contact Papa Legba to find out what has happened to Marie, and he informs her that Delphine gained the upper hand over her tormentor. Meanwhile, Zoe and Kyle return, Cordelia and Queenie unearth Misty, and Fiona says her goodbyes to the Axeman.
Four girls remain, and one of them must pass the Test of the Seven Wonders and prove that she is the Supreme.