Survivor count: 41,420

Katee Sackhoff has only a single brief appearance in this episode. Deleted scenes feature Kara being cleared for flight status along with other grounded pilots and her talking with the Cylon prisoners, including taking some revenge on Leoben.

This is the first episode without Michael Hogan, leaving Edward James Olmos and Mary McDonnell as the only actors to have appeared in every episode until Season 4. There was a scripted scene featuring Tigh, but Hogan requested it be cut because despite being a great scene, he felt that it didn't make sense given the context of Tigh's comments in the previous episode.

Dialogue in the opening confirms that Lee has resumed the rank of Major.

Tiffany Lyndall-Knight is credited as the Hybrid though she never appears in the episode.

This episode was preceeded by a parental advisory warning on its inital U.S. airing. This warning was repeated before the start of Act 3.

Dialogue establishes that Helo has been promoted to the rank of Captain.

Hotdog: Feel anything yet?
Racetrack: Yeah, I feel sick... sick of you bugging me!
Hotdog: You didn't touch any infected skinjobs.
Racetrack: It's not my fault you're clumsy.
Hotdog: You can kiss my infected ass.
Dr. Cottle: Well, you can kiss it, but it's not infected.

Adama: What the hell's so funny?
Lee: I think I just thought of a way to solve all of our problems. To get rid of the Cylon threat for once and for all. We can wipe them out. We can destroy the entire Cylon race.

Helo: Genocide? So that's what we're about now.
Lee: They're not human. They were built, not born. No fathers, no mothers, no sons, no daughters.
Helo: I had a daughter. I held her in my arms.
Lee: But she was half human. These are things, dangerous things. This is our one chance to be rid of them.
Helo: You can rationalise it anyway you want. We do this, we wipe out their race, then we're no different than they are.
Roslin: Captain, I respectfully disagree. The Cylons struck first in this war. And not being content with the annihilation of billions of human beings they pursued us relentlessly through the galaxies, determined to wipe us out.
Helo: They tried to live with us on New Caprica.
Roslin: What did you say?
Helo: They tried to live with us on New Caprica.
Roslin: You weren't on New Caprica. To my recollection you didn't set foot there, so out of the respect for the hundreds of men and women on your crew who suffered through that snake pit, I'm going to pretend I didn't hear that.

Helo: They're a race of people. Wiping them out with a biological weapon is a crime against... is a crime against humanity.

Adama: Posterity really doesn't look too kindly on genocide.
Roslin: You're making an assumption that posterity will define this as genocide. If they do, at least there'll be someone alive to hate us for it.