Charles Osgood presents. This week Tracy Smith chats to Fran Drescher. Mo Rocca visits Portland with the new series of 'Portlandia' beginning this week. Lee Cowan talks to Leonardo DiCaprio about 'The Wolf on Wall Street'. Susan Spencer looks at the idea of fruit flies curing cancer. David Martin has a report from the State of Union address. Lee Cowan also chats to Chiwetel Ejiofor about his Oscar hopes.