Grissom: Well, in this case we're going to recreate the flight from... 1630 hours on. You (Brass) are in 4B.
Brass: Lou.
Catherine: Lou -- the angry businessman. How about that?
Sara: I want to be Shannon. Good.
Warrick: The stewardess.
Sara: Excuse me -- it's "Flight Attendant".
Grissom: Catherine-- the doctor, 3E.
Catherine: Single mom. What an imagination you have.
Grissom: Max and Marlene, 2E and F. You two are married. Who wants to wear the pants?
Nick: CSI-3 seniority, sweetie.
Warrick: Yeah, whatever. You're henpecked anyway.
Sara (to Grissom): Let me guess -- you're the computer geek.
Grissom: In the interest of clarity, yes. Nate in 2C.

(while team is re-enacting a flight on the plane; Warrick and Nick are playing a married couple)
Warrick: (to Nick) Go protect me, honey!
Nick: (to Warrick) I'll protect you, buttercup.

Sara: I take it that's not blood?
Grissom: No, but it has protein in it.
Sara: Ah, the mile high club.

Grissom: So, dead guy in first class?
Brass: Las Vegas Air, I always heard it was a good time.

Grissom: If nothing criminal happened on that flight ... why isn't anybody talking to us?
Catherine: I'm going to go out on a limb here ... and say ... they're hiding something?
Grissom: Then we get to play hide-and-seek.

Gil: I got a dead body. And a crime scene with wings.

Gil: I need their shoes.
Catherine: Why are you telling me?
Gil: Cause you're the people person, right.
Catherine: Well, why don't you tell them that. They're not giving me bubkiss.
Gil: Please.

Catherine: (to passengers) Okay people, listen up. Shoes. Off. Now.

Gil: It took five people to kill him, but it would only have taken one person to save his life.

Gil: You all have different opinions, but you've taken the same point of view. You've put yourselves in the shoes of the passengers. But nobody put themselves in the shoes of the victim.

The spelling of the victim's last name that the CSIs use on the dummy is different than the spelling that appeared on his driver's license.

Title: Unfriendly Skies

Fly the Friendly Skies of United was a long running commercial tagline for United Airlines for more than thirty years, from 1965 to 1996.