When blood begins pouring from the faucets of a building, Mac, Det. Flack and Lindsay investigate and find a female doorman dead in the building's water tank.

After learning that the building in which their victim was found had six suspicious deaths over a 10 year period, Lindsay begins to question the science and wonders if the building is cursed. Mounting evidence seems to point to only one suspect, a doctor who swears he had no interaction with the victim, even though their lives seem intertwined.

Meanwhile, when a trend spotter is killed in Washington Heights after photographing a stylish teen, Stella, Sheldon and Danny question the marketing executive whose business was affected most by the victim's foray into the neighborhood.