Five days after surviving a horrific car accident, the woman who lost control of her car while driving home drunk is murdered in her hospital room shortly after coming out of a coma. Despite being paralyzed from the waist down, the doctors gave the victim a good chance for recovery, so the team must determine who wanted her dead in spite of her prognosis. Meanwhile, Sheldon returns to the hospital where he once worked as a promising surgeon and his investigation opens old wounds that led to his departure and caused him to become a medical examiner.