Zoe and Max’s explosive wedding reception sees Charlie jumping into the freezing water to rescue Zoe. He then suffers a heart attack and everybody needs to pull together to try and save him. At the same time the victim of a gunshot wound is brought into the Emergency Department.
Events continue to spiral out of control at the department as the tension rises as the team fight to save Charlie.
On her first day as a nurse, Louise finds herself struggling as a groom out on his stag night finds himself in danger as Iain faces a charge of assault.
A new Doctor arrives at the department in the form of Alicia Munroe and it proves to be a difficult shift dealing with a pregnant lady as Dylan returns to work.
The department finds itself the battleground when action is taken against racists as the staff try to control the chaos.
Iain and Dixie find themselves being pushed to the limit, but their rewards are great.
Cal manages to get back on an even keel.
Love manages to conquer all for one young couple. Charlie helps a father and daughter come to terms with their grief.
Jacob attempts to help a harassed teacher to agree to accept help but he also needs to take his own advice.
An unlikely patient shows up at the ED, and Jacob finds out that there's no justice in the world.
Alicia ends up being pushed to her limits and proves she's a great doctor.
Dixie ends up being forced to ignore her gut feeling. Cal faces every parent's worst nightmare.
A young couple have their wedding ruined by an unsupportive father. Jacob is able to prove that he can keep his cool with a difficult patient.
Christmas is around the corner but as the harsh conditions bring some people together, others find themselves being torn apart.
Connie does not want to bring her personal life affect her work, but in doing so she dismisses Jacob's instincts.
It's Christmas Eve and spirits are running high, but not everybody is feeling merry.
Cal finds it hard to deal with his recent shocking discovery but he soon finds out that he's much braver than he thinks.
Dixie becomes a hero but she is left feeling bittersweet about it.
The Emergency Department find themselves being pushed to the limit but they manage to pull together under difficult circumstances. Ethan is determined to give everybody the care that they deserve even though a black alert is called. He ends up failing to deal with a forced marriage and accidentally leaves a patient to die in the corridor.
A office worker believes she has won lots of money on the scratch card and unaware that it is a prank, quits her job as Noel finds himself the victim of a mugging.
Dixie attempts to help a desperate man deal with the truth. It’s also the day of her disciplinary, but things get off to a bad start when she is held up at an incident.
Having to put aside his dissatisfaction, Ethan returns to work and teams up with Lily to help a young girl with autism as he tries to settle back in.
Grace and Sam are back at the hospital and it transpires that Sam’s girlfriend Emma hasn’t been well and it’s now down to Connie to try and save her life.
Grace ends up having a panic attack and Sam convinces Connie that she’s not a good mother. Jacob realises that Connie doesn't want Grace to leave again, and tells her she needs to prove her love to her daughter.