Zoe and Max’s explosive wedding reception sees Charlie jumping into the freezing water to rescue Zoe. He then suffers a heart attack and everybody needs to pull together to try and save him. At the same time the victim of a gunshot wound is brought into the Emergency Department.
Events continue to spiral out of control at the department as the tension rises as the team fight to save Charlie.
On her first day as a nurse, Louise finds herself struggling as a groom out on his stag night finds himself in danger as Iain faces a charge of assault.
A new Doctor arrives at the department in the form of Alicia Munroe and it proves to be a difficult shift dealing with a pregnant lady as Dylan returns to work.
The department finds itself the battleground when action is taken against racists as the staff try to control the chaos.
Iain and Dixie find themselves being pushed to the limit, but their rewards are great.
Cal manages to get back on an even keel.
Love manages to conquer all for one young couple. Charlie helps a father and daughter come to terms with their grief.
Jacob attempts to help a harassed teacher to agree to accept help but he also needs to take his own advice.
An unlikely patient shows up at the ED, and Jacob finds out that there's no justice in the world.
Alicia ends up being pushed to her limits and proves she's a great doctor.
Dixie ends up being forced to ignore her gut feeling. Cal faces every parent's worst nightmare.
A young couple have their wedding ruined by an unsupportive father. Jacob is able to prove that he can keep his cool with a difficult patient.
Christmas is around the corner but as the harsh conditions bring some people together, others find themselves being torn apart.
Connie does not want to bring her personal life affect her work, but in doing so she dismisses Jacob's instincts.
It's Christmas Eve and spirits are running high, but not everybody is feeling merry.
Cal finds it hard to deal with his recent shocking discovery but he soon finds out that he's much braver than he thinks.
Dixie becomes a hero but she is left feeling bittersweet about it.
The Emergency Department find themselves being pushed to the limit but they manage to pull together under difficult circumstances. Ethan is determined to give everybody the care that they deserve even though a black alert is called. He ends up failing to deal with a forced marriage and accidentally leaves a patient to die in the corridor.
A office worker believes she has won lots of money on the scratch card and unaware that it is a prank, quits her job as Noel finds himself the victim of a mugging.
Dixie attempts to help a desperate man deal with the truth. It’s also the day of her disciplinary, but things get off to a bad start when she is held up at an incident.
Having to put aside his dissatisfaction, Ethan returns to work and teams up with Lily to help a young girl with autism as he tries to settle back in.
Grace and Sam are back at the hospital and it transpires that Sam’s girlfriend Emma hasn’t been well and it’s now down to Connie to try and save her life.
Grace ends up having a panic attack and Sam convinces Connie that she’s not a good mother. Jacob realises that Connie doesn't want Grace to leave again, and tells her she needs to prove her love to her daughter.
Big Mac does his best to apologise to Noel after he learns the truth as Lofty tries to deal with the pressure of his new responsibilities.
Following the Diana incident, Lofty has to decide what to say in his statement. Dylan wants him to make it clear that it was an accident. Lofty needs to decide whether to confess everything to Rita or carry the burden forever.
Iain isn't too pleased at being partnered with another paramedic as Emilie asks Caleb and Ethan to take her to one bay for the last time as Lofty attends a panel over what happened.
It is a terrifying day for Connie as Jacob finds himself in danger as Mercedes returns to the department with her son as Louise and Jack try to get Noel and Big Mac to sort their differences out.
Having been told Connie has to focus on Grace and can't be with him, Jacob goes out with the paramedics as Ethan reveals to Lily that he has Huntington’s as Connor turns to Max for help.
Jacob takes it upon himself to hunt down a dangerous drug dealer as Big Mac is unable to get Zoe to write another prescription and begins to suffer withdrawal symptoms as Connor calls Max for help instead of his mother.
The arrival of her ex in the department leaves Rita surprised as she finds old ghosts coming back to haunt her.
Big Mac’s secret begins to get on top of him and he’s not the only one who’s reached their limit as Rita suspects her ex is stalking her when she receives a number of complaints.
When Max sees Connor being bundled into a car, Max plays the hero and puts himself in danger as the department's newest nurse David Hide is rather quiet as Mark continues to bother Rita.
It is Elle Gardner's first day in the department as the newest consultant as it proves to be a baptism of fire as Zoe reveals to Max she is leaving for America, David finds himself struggling to fit it.