Noel wants to operate the Holby Radio over the hospital but feels nervous.
Jeff finds himself in a dangerous situation involving Samantha's husband as Charlie returns to work.
Rita is not happy after a patient turns out to be dishonest. Cal attempts to help a schoolgirl deal with her HIV,. Max convinces a rock legend to be honest.
Connie’s former boss Andrea shows up and risks a young boy’s life to hide her secret.Dixie is concerned about Tamzin and Jeff’s relationship.
Robyn and Lofty aren't happy at work. Noel sets Max up on a date. Connie asks Tess about Charlie's retirement.
A day out for several doctors ends in disaster as Jeff has plans to marry Tamzin.
A couple of former faces return to the hospital as the team comes together to say farewell to their friend Ash feels guilty about his colleague's death whilst Dixie throws herself into work and Cal is concerned after Ethan disappears from his hospital bed to attend the funeral.
Connie finds herself worried if she missed something as Cal and Ethan work together when they find a rare virus.
Zoe returns to the ED, bringing a surprise with her. Lofty treats a boy who is fed up of been stopped and searched. Dixie causes ripples through the department when shes rages about Jeff's death, clashing with Ash. Connie has a complaint made against her.
Briony is injured at the local derby game, it soon becomes apparent to Cal that she is having relationship issues with her fiancê Matthew. Raucous football fans find themselves in the ED after a fight gets out of hand. Ash struggles under the pressure. Dixie can't get over Jeff.
Ethan finds himself in charge of the ED one night where strange things start to occur.