U.S. Marshal Annie Frost and her partner Jimmy Godfrey are put on a case involving a serial killer that robs safes and kills the families who own them. He thwarts the Marshalls time and time again until one person makes him slip up. A new recruit, Luke, joins the team and together they hunt down to capture one of the Most Wanted criminals.
When the son of a State Trooper is brutally murdered, Annie Frost and the U.S. Marshal team are called in to track down fugitive Eduardo "El Lobo" Lopez . The case takes an unexpected turn when the Marshals discover that "El Lobo" is determined to reclaim what he believes is rightfully his, which ends in a showdown to stop "El Lobo" before he can find the couple who have his most prized possession.
After living a life in hiding using a false identity, fugitive Jack Drugganembarks on a vengeful killing spree in an attempt to return to his notorious mobster glory days. Boasting of his crimes and challenging the U.S. Marshals to catch him, tension arises between Annie Frost and Jimmy Godfrey as they race to track down Druggan before he can strike again.
A mother (Jennifer Morrison) goes on the run with her young daughter after a grisly murder. The team must reassess their strategy for capturing her, however, when doubts arise about the woman's mental state.
When a desperate fugitive convicted of defrauding investors of millions of dollars jumps bail and turns violent, the U.S. Marshals must find him before he disappears. Sparks fly between Annie and a bounty hunter who is also trying to capture the criminal, while Jimmy and Luke begin to bond.
On the hunt for fugitive Carson Puckett who is using explosives to get revenge, Anniegets injured and is forced to rely on bounty hunter Ben Crowley. In Annie's absence, under Jimmy's leadership, the team must use Daisy's tactical expertise to stop Puckett, and Luke is forced to step up to the plate.
When a U.S. Marshal impersonator, Bob McGraw, starts killing people in a misguided attempt to capture fugitives, he becomes one himself. The case becomes personal when McGraw turns the tables on U.S. Marshal Annie Frost. Meanwhile, Luke gets a surprise visitor who threatens his relationship with the U.S. Marshal team.
A serial killer escapes prison and U.S. Marshal Annie Frost must rely on jailed fugitive Mason Boyle for answers. The case takes a twist when the U.S. Marshal team discovers that the fugitive's ultimate victim is not who she appears to be.
Jackson Cooper is a fugitive with a dark past who manipulates his teenage girlfriend with promises of freedom from her father and a life filled with romance and adventure. When his deadly rapsheet is revealed, Jackson flees with his underage victim, destroying anything and anyone that comes in his way. U.S. Marshal Annie Frost must confront her own family history to gain the trust of Jackson's girlfriend, in order to track them down before it is too late.
U.S. Marshals Annie Frost and Daisy Ogbaa team up to catch small-town fugitives Karen Nelson and Ivy Collins, a duo who use their feminine wiles to lure innocent victims into participating in bank heists. Annie and Daisy become closer while working to break the fugitives' twisted , co-dependent bond before they continue down a self-destructive road.
U.S. Marshals Annie Frost and Luke Watson pursue fugitive Chris Novack, who takes the city of Houston hostage after escaping from the county courthouse, in violent pursuit of his best friend and girlfriend who have betrayed him. Meanwhile, the day's events allow Luke to understand his place in the force and Jimmy Godfrey looks at girlfriend, Natalie, in a new light.
When Pablo Cordova is arrested on suspicion of drug distribution and the lead witness in the case winds up dead, the U.S. Marshals discover the killer is his wife, Isabella. Isabella will stop at nothing to keep Pablo from going to jail and ensure that her family stays together, which ultimately puts Annie in serious danger. In a case that hits close to home, Marco is forced to recall his dark days with the narcotics division, while Jimmy must decide the fate of his relationship with Natalie.
U.S. Marshal Annie Frost's life remains in the hands of a dangerous drug cartel looking for retribution. While in captivity, Annie befriends another hostage and vows to return him home to the U.S. Back in the office, the rest of the Team devises a strategy to rescue Annie, but Jimmy and Marco's plan causes controversy with Luke, who disagrees with their rogue operation.
A corrupt police officer, Justin Tate, preys on single mothers in an attempt to get close to their young daughters. The U.S. Marshals work to stay two steps ahead of Tate, even casting U.S. Marshal Annie Frost as a ploy to lure him in. The case brings up raw emotions for Daisy while Luke is involved in an internal investigation that could potentially indict Jimmy and Marco.
The U.S. Marshals hunt for prison escapee David Bottner who launches his own desperate search for evidence of his innocence. He leads Annie and Jimmy through the horrific events that sealed his seven-year jail sentence, resulting in a twisted outcome. Reeling from a previous emotional case, Daisy unearths a hidden vice, which lands her in some trouble she might not be able to recover from.
Annie and Jimmy square off against Luke and Marco in an annual contest to clear as many backlogged warrants as possible. The teams hit the field, apprehending as many criminals as possible and racking up points until Annie and Jimmy face off against one of the worst of the worst -- threatening not only their score -- but also their lives. Meanwhile, Daisy opts out of the game to confront a man who caused her physical and emotional harm in the past. Running out of patience and legal strategies to put this man behind bars, Daisy makes a decision that will forever change her life and the U.S. Marshal team.
The U.S. Marshal team enlists the help of bounty hunter Ben Crowley to apprehend a dangerous criminal who has evaded arrest due to the protection of his loyal friends and family. Meanwhile, Annie experiences sleepless nights filled with strange dreams that include Ben, Jimmy and a dark premonition from her father.
U.S. Marshal Annie Frost must share the details of her past with the team in order to pursue a case that has put her father's life in danger. On a hunt to locate her father after two decades, Annie experiences flashbacks to her childhood, ultimately discovering the secret behind a lifelong betrayal.