Experiences of a group of six friends, centered on Susan and Steve, Susan's ex, Steve's ex, Susan's best girlfriend, and Steve's best friend. The central topics are strongly sexual, and deal with the sexual relationships of all six of them as they interact with each other and with outside individuals. While seeming to be a rip-off of "Friends", and, in fact, that is its original conceptual genesis, in the hands of highly talented writer-creator Steven Moffat the show goes much, much further into the complexities of finding a soulmate. Enhancing Moffat's excellent scripts are the well-matched comedic talents of Jack Davenport (Pirates of the Caribbean), Gina Bellman (Leverage), Sarah Alexander, Richard Coyle, Kate Isitt, and Ben Miles.
Susan is ready to give birth, and Steve is visited by Jeffina. Jeffina is both Jeff in female form, and Steve's pregnant math teacher from his childhood. Meanwhile, Oliver is promised some fun with Jane, but Jane can't seem to figure out that he has arrived.