With his recent failed attempt to rekindle Cheryl's affections weighing heavily upon him, Larry is in a deep funk. But Jeff's daughter's Bat Mitzvah is coming up, and Cheryl will be attending with her new romantic interest. Larry needs to find a date.

He also needs to find what's irritating his anus, and makes an appointment with a gastroenterologist. A disagreement with the office receptionist starts a rumor about Larry and sexual deviance with furry rodents. But while in the waiting room, he meets Paula, an attractive and charming woman who agrees to go on a date with him. But in traditional Larry fashion, he screws up the date and she goes home early.

At the last moment, Larry invites Loretta Black to the Bat Mitzvah. While at the event, he takes the opportunity to publicly address the sexual deviance/rodent issue.