Dexter was born with the biggest baby brain and already knows multiples of 5 when he was 3 years old. Now he's 8, he's one of the greatest geniuses in the world and has built his own super-secret, super-giant laboratory behind his bookcase. Inside are dozens of dazzling inventions that could change the world, chemicals that could do amazing things and the world's largest responding Computer called "Computer". Everything seems fine, huh? Think again. Dexter's noisy, silly big sister Dee Dee always finds away to sneak in and she destroys his inventions by playing around, and Dexter must keep her out of his lab and away from his brilliant inventions. Dee Dee isn't the only problem. Dexter's dad wants to make Dexter into an outdoorsman and a sportsman, while Dexter's mom can't stop cleaning and ordering Dexter to do chores. There's also Mandark, Dexter's rival who is jealous of Dexter's lab even when he has one of his own, and has fallen in love with Dee Dee. Dexter's Lab was the most popular Cartoon Cartoon on Cartoon Network for a long time and has ran for over 10 amazing years.