Julia Duffy reprises her role as Mrs. Hayfer for the first time in two seasons, and still seems to hate Drake after all this time.

Little Sibling is like the organization Big Brothers Big Sisters.

Becca: Mrs. Hayfer, the lunch ladies are fighting again!
Mrs. Hayfer: What is it about sloppy joe day that makes those women so violent? (she leaves) Helga? Helga?!
Josh: What are the lunch ladies fighting about?
Becca: They're not really.
Josh: Then why'd you tell her they were?
(Drake walks in)
Drake: Thank you, Becca.

Taylor: (To Josh, shouting over his headphones) Hey, did that ointment make your rash go away?
(Everyone snickers)
Josh: A little louder, I don't think they heard you IN AUSTRALIA!

Drake: Why does the principal wanna see me?
Josh: He doesn't.
Drake: I love you!
Josh: I know!

Josh: We're making our own cooking show.
Drake: What's it called? The Iron Boob?
Megan: (As she walks by) My joke.

Josh: We're making our own cooking show.
Megan: What's it called? The Iron Boob?

Mrs. Hayfer: Oh, and Drake, guess what?
Drake: What?
Mrs. Hayfer: I hate you.
Drake: I know.

Mr. Hayfer: Hi, I'm Gerald Hayfer. My wife is your teacher.
Drake: That's right.
Mr. Hayfer: She hates you.
Drake: I know.

Josh: I've just been watching Oprah... I mean football.

Megan: So you faked pancreas trouble to make Josh feel good?
Drake: That's right.
Megan: You are sick!

Drake: Would I lie to you?
Mrs. Hayfer: Let me think. Yes.

Mrs. Hayfer: Josh, please take Sammy to the nurse.
Josh: We don't have a nurse here-
Mrs. Hayfer: (yelling) To the nurse!
Josh: Come on, Sammy! (runs)

Soda parodies:
Moca Cola- Coca-Cola
Mountain Fizz- Mountain Dew
Diet Moca Cola- Diet Coca-Cola