When injured workers are brought into the ER after an explosion and chemical spill at a warehouse, the effects of the toxic material spread, forcing Dr. Carter to take control of the situation by setting up temporary medical quarters in the hospital cafeteria. Despite quick emergency measures, several staff members, including Dr. Weaver, suffer the effects of the fumes. Meanwhile, Dr. Corday helps treat the disaster victims, after risking her own life to save a man trapped in the collapsed warehouse. During the confusion, Dr. Ross takes a dangerous chance as he and Nurse Hathaway work to save a critically ill girl.