When a young mother of three is brought into the ER with potentially fatal stroke-like symptoms, Kovac and Sam race against the odds to save her life. Knowing that a controversial surgical procedure is his wife's only shot at a full recovery, a husband must make the unenviable decision to risk her life in order to save it. Meanwhile, Neela and Ray discover a dark secret when three ostensibly neglected children show up in the ER. Elsewhere, Carter finds himself in the midst of a love triangle when Wendall's professions of love force him to either cut the ties in Africa or lose her.