Peter: Look at all the garbage the damn Leafers are dumping on our lawn. The New York Times, New Yorker Magazine, the New York Mets.
Peter: Excuse me, is your refrigerator running? Because if it is, it probably runs like you - very homosexually.
Peter: Don't worry, I got an idea. An idea so smart my head would explode if I even began to know what I was talking about.
Stewie: Damn, must have pulled something playing hoops last week. (Goes to flashback of Stewie playing basketball.)
Stewie: I know you ain't puttin that rock up from here, cause you ain't got no J! (Stewie trips basketball player)
Baskeball player: Yo man, that's trippin!
Stewie: Brotha please, you're the one who's trippin'! Now go on! Cry home to your momma! She waitin' for ya!
Basketball player: Now don't make me stick my size thirteens up yo narrow ass!
Stewie: Oh, sweet! Bring it on bitch! Now how you gonna act?! (Basketball player walks away.) Jeeze! Bringin that trash in here. Dis is my house!!!
Peter: Excuse me sir, I believe you're in my seat and I had sex with your mother.
Man: What'd you say?!
Peter: What--about the seat or me plowin' your father's wife?
Quagmire: 'Hey there little lady. Why don't you turn around and show me your Lower East Side'.
Quagmire: Whoa, transvestite, back off! Wait a minute...pre-op or post-op?
Quagmire: Whoa, transvestite, back off!
Stewie: I'm the dog. I'm well read and have a diverse stock portfolio. But I'm not above eating grass clippings and regurgitating them on the rug.
Brian: I'm a pompous little antichrist who will abandon my plans for world domination when I grow up and wind up settling with a rough trick named Jim.
Stewie: Ooh, Lois, someone's wearing their ovaries on the outside.
Peter: Lois, brothers and sisters fighting is as natural as a white man's dialogue in a Spike Lee movie.
When Peter is running on the dock at the beginning of the episode, half his body dissapears!
The football team being shown on the game at the Drunken Clam are wearing green and black jerseys. But, following the NFL rules, one team should have been wearing white jerseys.
The letter Peter sent to Lois apparently just said "Dear Lois," then had spit on it. But when Lois holds the letter up we can see a lot more writing on the paper.
When Chris is talking about the leaves on the ground “Fred” is the yellow leaf and “Randy” is the brown leaf but when Meg holds them up they are both brown.
Glen asks the transvestite if 'she' is pre-op pr post-op. It's neither since Transvestites (or Cross-Dressers) are simply men who dress in women's clothes.
Transgenders, are people who believe they were born with the wrong gender that obtain surgery to alter their appearance.
Lois: This is mine... this is where my babies come from.
Apparrantly, one night in a bar OJ Simpson grabbed his wife's croch and made that very same announcement.
Peter: She floats like a butterfly and stings like when I pee.
Muhammad Ali was a boxer who often used the phrase "foats like a butterfly, stings like a bee."
Peter: Krypton Sucks
Krypton is the home planet of Superman. In the second Superman movie there were 3 bad guys from Krypton who came to earth and caused damage. The 3 villians in the bar are obviously them.
Obviously the title is a reference to the Lethal Weapon movies.