This episode marks the first appearances of Scorpius (Wayne Pygram) and Stark (Paul Goddard) on the series. Both characters would play a major role for the remainder of the series.
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Alyssa-Jane Cook returns as Gilina, Crichton's PK Tech Girl from the Zelbinion.
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Before he appeared as Scorpius, Wayne Pygram appeared in numerous Australian films and TV series including Time Trax and Fire.
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Paul Goddard, being best known at the time for his role as Agent Brown in The Matrix.
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Crichton's reference to Scorpius as Nosferatu was picked up later in the series when the Scorpius neural clone "Harvey" returned from the dead in a scene that paid homage to the classic 1920's film.
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The original conecpt of Scorpius was as an insectoid character who would have appeared much earlier in the first season.
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The title "Nerve" is taken from British racing author Dick Francis' first thriller. Ricky Manning's wife is a fan of the author, and Manning thought it was an appropriate title.
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Paul Goddard researched Jack Nicholson's performance in One Flew Over the Cuckoo's Nest and Brad Pitt's in Twelve Monkeys for keys to play Stark's madness.
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"Nerve" was the first time that an episode of Farscape ended with a To Be Continued.
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