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When blue hand individuals who foresaw and avoided their own death are apparently murdered, Demetri and MI6 agent Fiona Banks team up to find the person or persons responsible. Meanwhile, Simon tries to track down his missing sister and is forced to involve Mark, Bryce gets startling news about his medical condition, and Nicole has to decide whether to inform Bryce of Keiko's location.
Lloyd: God, I hope it all works.
Simon: We're simulating the Big Bang. What could go wrong?
Gordon Myhill: Initiate. Here goes nothing.
Lloyd: Or everything.
Bryce: How do you always know when I'm here?
Nicole: Mm, stalking. Internet. Paid informants. You know, the usual.
Jeff Slingerland: Poor Andy. I guess he thought he was in the clear. But I suppose the universe has to, uh, balance itself.
Demetri: Excuse me?
Jeff Slingerland: Life is energy, you see. As each new life begins, another ends. And if you mess with that balance, the universe pushes back.
Fiona Banks: There are no accidents anymore.