In the 30th Century, the once entertaining Harlem Globetrotters are now feared as they will humiliate any planet in the Universe who dares to play them. Feeling up to the challenge, Professor Farnsworth creates a group of mutant basketball players to go head-to-head with the Globetrotters. Farnsworth's secret winning ingredient is chronitons, time particles found in the Tempus Nebula. However, when the Planet Express crew removes the mutants from harvesting, they tip of the Time/Space Continuum causing forward motion of time to skip ahead.