Ed Westwick (Chuck Bass) does not appear.

This is the first appearance of John Shea (Harold Waldorf).

Dan: The pie has been secured. Thanksgiving no longer needs to be canceled.

(flashback)
Alison: (about Serena) Are you still thinking about your dream girl?
Dan: What?
Jenny: Uh huh.
Dan: No.
Jenny: Uh huh.
Dan: No, no. I was thinking about your stuffing, mom, which looks delicious.
Alison: Yeah.
Jenny: Well, keep dreaming. Maybe one day she'll actually know your name.
Dan: Yeah, maybe. And then I'll have something to be thankful for.

Blair: Mom, he's living in Europe ... with a man. You can't be all that surprised that he wants a divorce.

Serena: Mom is such a hypocrite. And all these years, she's been riding me about my behavior.
Eric: And here, she's just mad at you for being her.
Dan: And all the time my dad had been giving me advice based on a girl he dated ... a girl "a lot like Serena".
Jenny: Her mom.
Blair: If you think about it, it makes total sense that your mom was a groupie. I mean, only a woman that had completely satisfied her sexual appetite in her youth would ever marry your stepdads.
Serena: Blair, can we not talk about my mom's appetite?
Dan: No, or who satisfied her.
Serena: That's just --
Serena, Dan, Jenny and Eric: Gross!

Gossip Girl: (voiceover) As per Gossip Girl Thanksgiving tradition, I'm trading my laptop for stove-top. And for the next sixteen hours, the only thing I'm dishing is seconds. When the cat's away, the mice will play. Have fun, little rodents!

Serena: Tell me you didn't sleep with Chuck for revenge.
Blair: Well it wasn't because I like his natural musk.

Blair: Nothing hurts more than sleeping with a best friend.
Serena: Way to prove a point.
Blair: Well, I learned it from the master.
Serena: If you're sleeping with Chuck, I'd say you've become the master.

Alison: Just in time, but I thought you were going to bring pie.
Dan: I did, but it kind of got run over by a taxi because I was trying to help this girl stay out of traffic.
Alison: Ah, well who needs dessert when we've got a real live hero in our midst? (to Jenny) Did you hear that? Your brother just saved a girl.
Jenny: I thought you had to be near a girl for that to happen.
Dan: Not just any girl, the girl.
Jenny: Oh, the blond you stalk at school?
Dan: Just the one.
Alison: A thing for blonds. You are your father's son.
Dan: Not just any blond, apparently I like the ones that get drunk on Thanksgiving and almost die.
Alison: Well your dad liked them dangerous and troubled too.
Dan: You were dangerous?
Alison: Who said I was talking about me?

During the flashback, it is said to be Thanksgiving one year ago, which would make it 2006. However, at the Humphrey's during the flashback, there is a poster for the 2007 film Zodiac.

Episode Title: Blair Waldorf Must Pie!

The episode title is a take on the 2006 movie, John Tucker Must Die. The movie starred series star Penn Badgley (Dan Humphrey).