Rusty begins his freshman year at Cyprus-Rhodes University and decides to rush a fraternity. However, his older sister, Casey, who's already a sorority member, doesn't want her younger brother to be a part of the Greek scene as well.
Casey tries to get back at Rebecca Logan for sleeping with Evan by giving her the challenging scavenger hunt assignment for initiation. Things take a turn when Rebecca is arrested by campus security while she's in the faculty locker room with a camera.
During Mixer night on Greek Row, Rusty needs a date so Cappie sets him up with a "sure thing," but it turns into a dating disaster. Meanwhile, Calvin volunteers to be Zeta Beta Zeta's errand boy in order to help Ashleigh plan the military-themed mixer, but Ashleigh misreads Calvin's enthusiasm for him having a crush on her.
A fraternity floor-hockey tournament causes Evan to doubt Casey's allegiance to his Omega team; Dale devises a plan to help the awkward Rusty play for the Kappas.
Rusty's science background becomes invaluable to Kappa Tau when its volcano for a Mount Vesuvius bash fails to blow its top. Meanwhile, Casey meets Evan's parents, but she's overshadowed by Rebecca's surprise appearance.
Sorority secrets are revealed when inclement weather mars Casey's slumber party for Zeta pledges. Meanwhile, Cappie receives a surprise visit from a mysterious girl.
As a demanding week of midterm exams approaches, Rusty considers a sure-fire way to keep his grades up while not missing out on the fun at the Kappa house. Meanwhile, sparks fly when Casey and Cappie are paired on a school project.
A snafu in Zeta's community-service schedule puts Casey in the unfamiliar position of working with Dale's religious group; lovesick Rusty and Cappie seek distractions from women.
Both Casey and Frannie are nominated for the title of Omega Chi Sweetheart, which creates a cat fight between the two. Meanwhile, Rusty and Jen K. continue to get closer, but Dale, Rusty's roommate keeps getting in the way of them having more private time together.
An article about the Greek system at Cyprus-Rhodes is published in the school newspaper, which sets both the fraternities and sororities into a tailspin.
The new semester finds Casey adjusting to being named sorority president now that Zeta she has split up with Evan and fallen from grace. Meanwhile, Rusty needs to forget about Jen K., Calvin thinks about rejoining the Omegas, and Cappie and Rebecca keep their relationship quiet. The all-Greek carnival gets a special performance from The Plain White T's.
Seeing that the sorority sisters are bored with the new rules at ZBZ, Casey decides to follow all of the rules, but break them at the same time. To do so, she teams up with Cappie and Kappa Tau to throw a Great Gatsby themed prohibition-esque party.
When Cappie seeks revenge on Evan for blowing the whistle on recent underground activities, Omega Chi becomes the victim of pranks from Kappa Tau. Meanwhile, Rebbecca's new relationship causes her rivalry with Casey to intensify.
A rivalry of the Kappas and Omegas becomes a seesaw battle of practical jokes, causing a strain between the friendship of Rusty and Calvin. Meanwhile, Casey intends to bring and end to the overbearing supervision of Lizzie.
As the Greek Ball approaches, Casey and Cappie remember how a friendship was destroyed during their freshman dance, while Casey recalls an act by Frannie which had an influence on her life.
Rusty and Casey are both determined to move on after their failed relationship, Dale helps Rusty find a date, while Casey comes to terms with her break up with Evan when most of her sorority sisters want to reunite with the Omegas.
Rusty worries about Kappa's reputation as being a party house, now that Parents Weekend is approaching. Rebbecca has yet to tell her father about dating Cappie, a slacker, and Dale wishes he had not invited his parents at all.
Casey gets a crush on a Lambda Sigma brother after the Zeta Beta sisters are pitted against each other in a series of bizarre fraternity coaching competitions. Rebecca's relationship with Cappie is put to the test when she is assigned to help the Kappa Taus.
Ashleigh's preferential treatment from Casey causes dissension within the ranks of the Zeta house. Meanwhile, Cappie takes on the campus rules along with Dales ever growing anti-greek group, and Rusty adjusts to a new relationship.
With the Cyprus-Rhoades prohibitions over with, Kappa Tau and Omega Chi compete for campus supremacy by throwing competing parties. Meanwhile, Casey is attracted to a new frat member, and Rusty reconsiders his relationship with Tina.
Rusty has an identity crisis after Cappie decides all the Kappa's should practice using their fake id's now that spring break is upon them. Meanwhile, Casey wonders about her future when after asking Evan's for help in studying for her law-school admissions test.
Casey decides to finally leave the past behind and cut loose as the Cyprus-Rhoades students head out to the beach for Spring break. Feeling out of place, Rusty cuts his vacation short and looks up some old friends on his way back to campus.
The annual Greek week competition finds Rusty and Calvin striving for a neutral friendship zone despite having opposing house loyalties. Meanwhile, Casey must figure out what will happen with Rebecca because of her wild spring break activity, and her continued bad behavior isn't helping much.
Casey and Ashleigh discover they have a crush on the same guy as they prepare to attend a ZBZ crush party. Meanwhile, Elsewhere, Rusty turns to Max, his new RA, for education advice.
In hopes of helping Ashleigh with her debts, Casey and Rusty organize a casino night. Elsewhere, Evan struggles to accept the fine print concerning his trust fund, and Rebecca wants to give Cappie money so he can purchase a car.
Cappie fears a Kappa Tau mystery will be uncovered by Rusty. Meanwhile, Casey begins having feelings for Max; as Ashleigh helps cheer up Rebecca; and Calvin seeks out more gay friends at a gay bar at his boyfriend's suggestion, surprised by who they find there.
The pledges at Kappa Tau fight back after receiving poor treatment. Elsewhere, Evan conspires to use Calvin and Michael's relationship to help a brother who's failing.
The ZBZ girls head to Florida to attend a sorority convention, while Casey frets that Frannie will change some of the election rules. Elsewhere, Kappa Tau tries to raise some money by hosting an engineering-department party, but the good times get out of hand.
Cassie brings Max to the formal dance where he is sized up by the sorority sisters. Meanwhile, Ashleigh attempts to find a date for Rusty, while Cappie and Rebecca slip away to an empty ZBZ house while the others are away at the formal.
Casey retaliates when Frannie starts spreading lies, just as the ZBZ presidential election nears. Elsewhere, Calvin's cheating on Michael creates fallout, and Rusty bumps into his ex, Jen K., while out on a date with another girl.
Rusty is hesitant to share with Dale the secret he has uncovered concerning Dale's friend. Elsewhere, Ashleigh adjusts to her new role in ZBZ while getting caught up in her friends rivalry.
Casey struggles to make a decision between an internship and Max's plans as Summer approaches, which has her so confused that she has a dream in which she is being counseled by Lauren Conrad. Elsewhere, Rusty is determined to make it through Hell Week by doing anything that is asked of the pledges.
Casey has secret plans on moving out of her sorority house upon her return from her summer internship. Elsewhere, Andy, Calvin's high school buddy, begins his freshman year and is courted by Calvin and Rusty's fraternities. Rusty adjusts to life in the Kappa Tau house.
Rush Week finds an eager sophomore in Rusty, attempting to recruit Andy to pledge Kappa Tau, while Calvin tries to sway Andy towards Omega. Elsewhere, Casey and Ashleigh doubt that Rebecca is the mole, but believe she may be a double agent for Frannie.
Cassie seeks advice from Prof. Freeman in helping Max and Cappie get along with each other. Elsewhere, Rusty and Andy become rivals trying to impress a transfer student; and a guy who is getting loads of attention from the ZBZ girls, has his eyes only on Ashleigh.
Rusty doesn't want to become the big brother for Andy due to his hookup with Jordan. Elsewhere, Patrick, Evan's brother, pays a visit and asks for money. Also, Casey and Rebbecca believe they know who is responsible for the stolen food from ZBZ.
Casey hopes to prove the passion of the ZBZ's sisterhood to Frannie and also win a new pledge in Jordan, by challenging the IKI's to a game of dodgeball. Meanwhile, Rusty creates a plan to get Dale out of their apartment occasionally, but it backfires as both become evicted.
Kiki, a ZBZ alum, is returning to CRU for her wedding, which means Frannie and Casey will be bridesmaids together, which Casey is not too happy about. Meanwhile, after learning of the wedding, Max proposes to Casey; Rusty and Jordan bond while picking up flowers and even share a kiss, and Robin and Rebecca share a kiss at a bachelorette party.
The KT's rush to return a stash of campus goods which were stolen, before security can catch them. Elsewhere, Casey helps Max meet a visiting professor who is in need of an intern, by sneaking him into a faculty party. Ashleigh considers making her relationship with Fisher public.
Rusty attempts to solve a mystery involving a secret service he ran across on campus in hopes of impressing Cappie. Meanwhile, some of Frannie's defectors from ZBZ house have asked to return, and Rebecca seeks dating advice from Calvin as she readies to go out with Robin.
Awkward study teams seem to be forming as midterms approach: Cappie's team features only women, from Casey to the pair of girls he's been dating, and Rusty's art history group which contains Jordan. Meanwhile, after having her car towed away, Rebecca seeks the help of Evan to retrieve her laptop.
Rusty's new romance with Jordan is interfered with by a lonely Casey. After finally getting a new roommate, Calvin discovers the guy is hiding a surprising secret. Meanwhile, Evan and Cappie's rivalry is renewed over a secret society member.
Rusty and Ashleigh try hard to win the float competition, while Casey and Cappie try avoid each other as Homecoming Week heats up. Elsewhere, Evan gets word that he may lose his trust fund, and Ashleigh uncovers one of Fisher's secrets.
The season 2 finale finds an "End of the World" party being hosted by Kappa Tau, and Casey struggling with her conflicting feelings between Cappie and Max. Meanwhile, Ashleigh is accused of sabotage of the homecoming float, and a purity pledge has been taken by Dale and Calvin.
Cassey deals with living the single life now following Cappie's rejection, while Cappie learns about Max's leaving. Elsewhere, Rusty risks losing his honors program if he can't raise his organic chemistry grade.
It's father-daughter weekend at ZBZ, as tension builds at the house after the secret of whom Rebecca's kissed is revealed. Meanwhile, Rusty tries to impress Jordan's father with sports, and Dale and Cappie explore different religions.
As Rusty and Jordan become closer, they begin to realize they are the two finalists in a campus-wide game. Elsewhere, Calvin and Grant have a romantic dinner off of campus, and Casey wants to save the annual ''undies run," which faces elimination.
Rusty needs help if he's going to improve his grades. Casey plans an alcohol-free house-to-house party.
Casey and Ashleigh work on raising the house rank of ZBZ. Elsewhere, Rusty and Jordan examine their relationship.
Thee ZBZs are working hard to milk Founders Weekend, in hopes of turning around the house's slipping status. Casey gets involved with a wealthy alum's grandson, Rebecca and Ashleigh go head-to-head in a fund-raising challenge. Rusty tries his best to keep Jordan from dropping out of school.
Cappie and Evan's friendship is investigated by Casey. Rusty goes with Dale and Calvin to a comic book convention as a distraction from Jordan. Ashleigh and Fisher decide to begin dating again.
In order to restore ZBZ's popularity, Ashleigh resorts to unusual measures to ensure a successful mixer. Evan's reputation in Omega Chi falls apart once they find out that he gave up his trust fund.
While most people are off campus for Thanksgiving break, Casey and Rebecca plan a dinner for the students remaining. Also, Rusty works on his engineering project.
Cappie and Casey go public, and Omega Chi and Kappa Tau get serious about pranking. Things heat up when Song Fest pits ZBZ against Gamma Psi. Rusty and Dale take their rivalry out of the lab.
Winter Break is over, and the ZBZ house is on fire with guilt over the Gamma Psi house they may have burned down. Stress eating and denial take over as Casey tries to keep her sisters from losing it. But she's not doing any better herself.
Casey suffers feelings of guilt over the fire; Rusty's popularity soars after he wins the grant competition.
It's co-ed softball time on Greek Row, and the winner gets five more points toward House of the Year. Ashleigh and Casey are determined to shake their fourth-ish status and get back at the Gamma Psis.
Casey's got the future on her mind. Some of the legislation she worked on last summer during her internship is making its way through congress. She drops the G word (Graduation) on Cappie, and immediately regrets it.
Caught shopping for lingerie, Cappie challenges Casey to see who finds the most romantic gift.
Evan finds Calvin making a music gaylist in the living room, and they talk about Rebecca's swift exit from the party.
Everyone at Cyprus Rhodes is preparing for Mardi Gras festivities, except for Casey, who must prepare for the biggest test of her life - the LSAT. While Casey continues to push Cappie to declare a major and make plans to focus on the future, he is too busy announcing the next parade at the Kappa Tau Mardi Gras party.
Tension increases between Casey and Cappie when his parents suggest a camping trip.
A golf tournament will determine the top fraternity on campus; Katherine agrees to bring back the Greek Goddesses Pageant; Calvin and Grant feud over where to spend spring break.
The gang returns to Myrtle Beach for spring break; seniors consider their futures.
Casey digs into why she was rejected from CRU law school, while Calvin and Rebecca adjust to their new duties as presidents.
The KT's attempt to recruit new pledges, Tegan (Charisma Carpenter) returns to help the ZBZ's maintain their top position.
Prepared to console his brother-less roommate, Rusty is met with a surprise when he finds that Dale is actually pledging a fraternity - and it's not Kappa Tau - which clearly affects their friendship. However, Rusty and Dana hatch a scheme to get his best friend back during a Murder Mystery Party
Beaver seeks help from Casey to rewrite a paper when his teacher discovers that he bought his original paper online. Casey is frantic because Katherine, doesn't believe in study groups. Rebecca tries to make Evan jealous when she feels he is not paying enough attention to her. Rusty and Dana work on a presentation to the school in order to receive funding for Rusty's project.
Cappie tries to impress Peter's dad, and Calvin discovers Heath's secret.
Casey and Cappie find themselves facing a harsh reality after spontaneously spending the night together at the ZBZ house. Adding to Casey's personal sense of responsibility, Katherine confides in Casey about her own new romance and asks Casey's advice.
When the friends gather for Calvin's birthday, Casey and Ashleigh see each other for the first time since their fight, and Casey finds out that Ashleigh is dating Professor Segal. Meanwhile, Rebecca begins to wonder if she and Evan will make it through law school as a couple.
Casey and Evan continue their feud during a mock trial in Professor Segal's class, making the case personal instead of a simple class assignment; Rusty and Calvin must save Dale from being humiliated by the Omega Chis during the Pledge Talent Show.
When Rebecca finds out that ZBZ is up for the Golden Lily award for being the best chapter in the country, she recruits the help of former house president.
Set amidst the battle to save the Kappa Tau house, brotherhood and friendships are tested, while troubled and budding relationships will either be resolved or dissolved. Will Casey and Cappie face their futures together? Will Cappie and Evan be able to put their embattled college past aside and salvage their friendship? What's in store for Rusty and Ashleigh? Calvin and Heath? Evan and Rebecca? Will Dale get over his unrequited love for Casey? And viewers will finally learn the answer to two of the burning questions posed over the years – now that Cappie has declared a major, does he ever plan to graduate? And what is his real name?