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Season 5

79 :05x01 - Dream a Little Dream of Me (1)

Sep/25/2008
As Meredith and Derek begin to find that their "happily ever after" is anything but easy, Cristina develops a crush on a military doctor who brings in a trauma patient. Meanwhile, the Chief and his staff cope with the news that Seattle Grace is no longer considered a top-tier teaching hospital.
Guest Stars: Lauren Stamile as Rose (Nurse Rose) | Kevin McKidd as Dr. Owen Hunt (Military Doctor, Pulls Icicle Out of Christina) | Mariette Hartley as Betty Kenner (Patient: Car Crash with Amnesia) | Cliff DeYoung as Phil Loomis (Patient: Car Crash Victim, Husband of Anna Loomis) | Bernadette Peters as Sarabeth Breyers (Patient: Car Crash Victim, Wife of Michael Breyers) | Kathy Baker as Anna Loomis (Patient: Car Crash Victim, Wife of Phil Loomis) |
Co-Guest Stars: Molly Kidder as Intern Megan | Joy Osmanski as Intern Lucy | Terrance Christopher Jones (1) as Paramedic | Amrapali Ambegaokar as Intern Dani | Mark Saul as Intern Steve | John Getz as Michael Breyers (Patient: Car Crash Victim, Unable to Speak)
Director: Rob Corn
Songs: Other Lives -- Black Tables, Emiliana Torrini -- Jungle Drum, Jade McNelis -- Wins, Beck -- Youthless

80 :05x02 - Dream a Little Dream of Me (2)

Sep/25/2008
While Meredith and Derek continue in their new relationship, Cristina continues to get to know the military doctor as they treat his trauma patient.
Guest Stars: Kathy Baker as Anna Loomis (Patient: Car Crash Victim, Wife of Phil Loomis) | Bernadette Peters as Sarabeth Breyers (Patient: Car Crash Victim, Wife of Michael Breyers) | Cliff DeYoung as Phil Loomis (Patient: Car Crash Victim, Husband of Anna Loomis) | Lauren Stamile as Rose (Nurse Rose) | Mariette Hartley as Betty Kenner (Patient: Car Crash Victim with Amnesia) | Kevin McKidd as Dr. Owen Hunt (Military Doctor, Pulls Icicle Out of Christina) |
Co-Guest Stars: Molly Kidder as Intern Megan | Mark Saul as Intern Steve | Joy Osmanski as Intern Lucy | Amrapali Ambegaokar as Intern Dani | John Getz as Michael Breyers (Patient: Car Crash Victim, Unable to Speak) |
Uncredited: Jeffrey Dean Morgan as Denny Duquette
Director: Rob Corn
Songs: Greg Laswell -- And Then You, Jont -- Another Door Closes, The Rescues -- Crazy Ever After (Acoustic), Steve Reynolds (2) -- Mistaken Identity, The Perishers -- Never Bloom Again, Bon Iver -- Skinny Love, Taylor Swift -- White Horse

81 :05x03 - Here Comes the Flood

Oct/09/2008
When the plumbing springs a leak, chaos breaks out at Seattle Grace as the Chief tries to put in place new teaching methods. Meanwhile, George takes his residency exam; and Derek attempts to get Meredith's roommates to move out, much to their surprise.
Guest Stars: Samantha Quan as Shelly Boden (Patient: Young Woman With Colon Cancer) | Jim Ortlieb as Jack O'Brien (Patient: Has Bad Luck, Abdominal Aortic Anneurism) | Daniel J. Travanti as Barry Patmore (Patient: Chronic Headaches) | Amy Madigan as Dr. Wyatt (Meredith's Therapist) |
Co-Guest Stars: Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Mark Saul as Intern Steve | Joy Osmanski as Intern Lucy | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | Ariel Felix as Anesthesiologist | Tymberlee Hill as Intern Claire | Kate Anthony as Nurse Kate | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Nelson Mashita as Dr. Bennit Epstein (George O'Malley's Exam Proctor) | Suzy Nakamura as Jenn Smith (Patient Shelly Boden's Sister)
Songs: Sia -- Cares at the Door, Emiliana Torrini -- Ha Ha, Little Jackie -- LOL, Erin McCarley -- Pitter-Pat, Santogold -- Say Aha

82 :05x04 - Brave New World

Oct/16/2008
Meredith is sent into a state of panic when Derek finds her mother's diary in the house. Meanwhile, Callie stresses while preparing for her first date with Erica. Later, Cristina stumbles across a part of the hospital no one has ever seen before.
Guest Stars: Max Burkholder as Duncan Pailey (Patient: Young Boy Scheduled for Heart Surgery) | Kathleen Early as Dr. Daisy Pepman (First Year Dermatology Resident) | Steven W. Bailey as Joe (The Bartender at Emerald City Bar) | John Sloan as David Pailey (Father of Duncan Pailey) | Bre Blair as Lauren Pailey (Mother of Ducan Pailey) | Larry Brandenburg as Arnie Grandy (Patient: Brain Tumor, Husband to Marianne Grandy) | Amy Aquino as Marianne Grandy (Wife to Arnie Grandy) |
Co-Guest Stars: Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Mark Saul as Intern Steve | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Carol Ann Susi as Mrs. Dorsokowski (Patient: In Clinic, Has a Rash)
Director: Eric Stoltz
Songs: Brett Dennen -- Ain't Gonna Lose You, Patrick & Eugene -- Altogether Now, Emiliana Torrini -- Big Jumps, The Whitest Boy Alive -- Done with You, Bernadette Moley -- Love to Me, The Rescues -- My Heart with You, The Bird and the Bee -- My Love, Joshua Radin -- One of Those Days

83 :05x05 - There's No 'I' in Team

Oct/23/2008
Bailey leads a team for a "domino procedure" in which each surgery is dependent on the one before it. Meanwhile, Derek receives sole credit for the study he and Meredith worked on; Lexie tries to get George to see her in a different light; and Sloan gives Callie relationship advice.
Guest Stars: Saige Thompson as Lindsay Herman (Patient: Domino Surgery, Donating Kidney) | Colleen Flynn as Nancy Mercer (Patient: Domino Surgery, Donating Kidney) | George Newbern as Stan Mercer (Patient: Domino Surgery, Receiving Kidney) | Carl Lumbly as Kurt Walling (Patient: Domino Surgery, Receiving Kidney) | Kevin McKidd as Dr. Owen Hunt (Sitting at Bar at End of the Episode) |
Co-Guest Stars: Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Mark Saul as Intern Steve | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Janina Gavankar as Intern Lisa | Joyce Brew as Nurse | Rajni Kareer as Mrs. Patel (Patient: Domino Surgery, Donating Kidney) | Eileen Fogarty as Mrs. Chen's Sister (Patient: Domino Surgery, Donating Kidney) | Ren Hanami as Mrs. Chen (Patient: Domino Surgery, Receiving Kidney) | Steven W. Bailey as Joe (The Bartender at Emerald City Bar) | Leslie Odom, Jr. as PJ Walling (Patient: Domino Surgery, Donating Kidney)
Director: Randall Zisk
Writer: Jenna Bans
Songs: Brandi Carlile -- Again Today / Hiding My Heart, Greg Laswell -- Comes and Goes (In Waves), Lenka Kripac -- Live Like You're Dying, Erin McCarley -- Love, Save the Empty, Emilie Mover -- Ordinary Day, Shady Bard -- These Quiet Times

84 :05x06 - Life During Wartime

Oct/30/2008
The Chief gives Bailey new responsibility in order to help her to be one of the best surgeons at Seattle Grace. Meanwhile, Owen Hunt, the new head of trauma, clashes with the current staff's methods and abilities.
Guest Stars: Scott Haven as Randy Begler (Relative of Patient Tori Begler) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) |
Co-Guest Stars: Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Janina Gavankar as Intern Lisa | Mark Saul as Intern Steve | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Lauri Johnson as Grandma Ruth (Grandmother to Patient Tori Begler) | Brandon Scott (2) as Intern Ryan | Adair Tishler as Tori Begler (Patient: Has Inoperable Tumor) | Sheila Shaw as Michelle Begler (Relative of Patient Tori Begler) | Michael Hagiwara as Charles Hyatt (Patient: Treated by Izzie in Trauma Centre) | Chet Grissom as Uncle Pat (Uncle to Patient Tori Begler) | Brooke Blanchard as Jill the Paramedic
Director: James Frawley
Writer: Mark Wilding
Songs: Greg Laswell -- Days Go On, El Perro Del Mar -- From the Valley to the Stars, Raining Jane -- Prelude, Vampire Weekend -- Walcott

85 :05x07 - Rise Up

Nov/06/2008
When the Chief makes an announcement that a solo surgery is up as an award, the residents are sent into a frenzy all trying to get an edge over one another. Meanwhile, Derek asks Bailey for advice after Cristina continues to interfere in his relationship with Meredith. Elsewhere, Erica uncovers a shocking connection between a resident and a patient.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Bonnie Bartlett as Rosemary Bullard (Patient: Brain Tumor) | Tom Verica as Michael Norris (Patient: Heart Surgery) | George Coe as Ed Bullard (Husband of Patient Rosemary Bullard) | Brandon Scott (2) as Intern Ryan | Kevin McKidd as Dr. Owen Hunt (Trauma Center Surgeon) |
Co-Guest Stars: Gordon James as Tech | Shi Ne Nielson as Paramedic | Fidel Gomez as Morgue Attendant | Mark Saul as Intern Steve | Gloria Garayua as Intern Graciella | Avery Clyde as Elyse (Wife of Patient Michael Norris)
Director: Joanna Kerns
Songs: Brazilian Girls -- Good Time, Erin McCarley -- Gotta Figure This Out, Psapp -- I Want That, Shady Bard -- Torch Song

86 :05x08 - These Ties That Bind

Nov/13/2008
Sadie, one of Meredith's oldest friends, is brought on as an intern at Seattle Grace; however, Meredith's friends are less than welcoming to her. Meanwhile, Lexie leads the interns on a unique training session; and Virginia, a new surgeon, brings new rules to the O.R.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Ed Lauter as Timothy Miller (Patient: Homeless Man, Impaled in Garbage Truck) | August Schellenberg as Clay Bedonie (Patient: Navajo Indian, Heart Transplant) | Mary McDonnell as Dr. Virginia Dixon (Cardiac Surgeon With Asperger's Syndrome) | Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) |
Co-Guest Stars: Nicole Cummins as Paramedic Jill | Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Molly Kidder as Intern Megan | Mark Saul as Intern Steve | Gloria Garayua as Intern Graciella
Director: Eric Stoltz
Writer: Stacy McKee
Songs: Seabird -- Falling for You, Walking Sleep -- The Uniform (as The Flying Tourbillon Orchestra), Lenka Kripac -- Trouble is a Friend

87 :05x09 - In the Midnight Hour

Nov/20/2008
Meredith, Cristina and Bailey must save Lexie and Sadie after a routine surgery goes terribly awry. Meanwhile, Owen and Derek treat a man injured while sleepwalking.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Madeline Carroll as Ivy Soltanoff (Daughter of Patient Arthur Soltanoff) | John Allen Nelson as Arthur Soltanoff (Patient: Sleepwalking, Night Terrors) | Joshua Malina as Seth Hammer (Husband of Patient Lauren Hammer) | Leslie Grossman as Lauren Hammer (Patient: Hypochondriac, Fecal Transplant) | Melissa George as Sadie Harris (New Intern, Appendectomy) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) |
Co-Guest Stars: Nicole Cummins as EMT | Jody Sclavos as ER Nurse | Winston Story as Intern Leo | Molly Kidder as Intern Megan | Mark Saul as Intern Steve | Gloria Garayua as Intern Graciella | Joseph Williamson as Intern Pierce | Brandon Scott (2) as Intern Ryan
Director: Tom Verica
Songs: Meiko -- Boys With Girlfriends, Tina Dico -- No Time to Sleep, Lisa Hannigan -- Ocean and a Rock, Waz -- Ordinary Girl, Dido -- Quiet Times

88 :05x10 - All By Myself

Dec/04/2008
Cristina wins the first solo surgery among the residents, but is forced to give it up and choose who will perform the surgery in her place. Meanwhile, Mark heads up a procedure that will allow his patient to regain their ability to speak. Elsewhere, Callie tries to figure out if Sadie is being friendly to her or hitting on her.
Guest Stars: Kay Panabaker as Emma Anderson (Patient: Car Crash, Sister to Holly Anderson) | Rosalind Chao as Kathleen Patterson (Patient: Larengectomy, Unable to Speak) | Christa B. Allen as Holly Anderson (Patient: Car Crash, Sister to Emma Anderson) | Brandon Scott (2) as Intern Ryan | Tzi Ma as Mr. Patterson (Husband of Patient Kathleen Patterson) | Mary McDonnell as Dr. Virginia Dixon (Cardiac Surgeon With Asperger's Syndrome) | Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Kevin McKidd as Dr. Owen Hunt |
Co-Guest Stars: Kerry Carney as ND Resident | Vince Cefalu as ND Patient | Keeshan Giles as Paramedic #2 | Larkin Campbell as Mr. Anderson (Father of Holly and Emma Anderson) | Perry Smith as Mrs. Anderson (Mother of Holly and Emma Anderson) | Gloria Garayua as Intern Graciella | Mark Saul as Intern Steve | Zibby Allen as Nurse
Director: Arlene Sanford
Writer: Peter Nowalk
Songs: Max Morgan -- Secret, Kanye West -- Street Lights, Sugarush Beat Company -- They Said I Said, Ray LaMontagne -- Winter Birds

89 :05x11 - Wish You Were Here

Jan/08/2009
Bailey pairs up with Dr. Arizona Robbins, Seattle Grace's new pediatric surgeon, to help save the life of a young patient. Derek is furious when a death row inmate is checked in to the hospital; Cristina and Meredith's friendship continues to erode; Callie and Sloan work through their attractions to Sadie and Lexie; and Izzie confesses to Alex that she has been seeing Denny.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Robin Pearson Rose as Patricia (Richard Webber's Secretary) | Steven W. Bailey as Joe (The Bartender at Emerald City Bar) | Perrey Reeves as Margaret (Patient: Benign Tumor, Breaks Bones Easily) | Samantha Mathis as Melinda Prescott (Mother of Patient Jackson Prescott) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Suregeon, Takes Over for Dr. Kinley) | Eric Stoltz as William Dunn (Patient: Death Row Inmate) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) |
Co-Guest Stars: Kevin Clarke as Paramedic | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | John Sloman as Dr. Jordan Kinley (Chief of Pediatric Surgery, Dies of Heart Attack) | Aaron Refvem as Jackson Prescott (Patient: Child, Bowel and Liver Failure)
Director: Rob Corn
Songs: The Coral Sea -- Ah, Ah, Ah, Daniel Powter -- Am I Still the One (featuring Linda Perry), Tandy -- Home, Santogold -- Lights Out, Dido -- The Day Before the Day, Ben Folds -- You Don't Know Me (featuring Regina Spektor)

90 :05x12 - Sympathy for the Devil

Jan/15/2009
Derek's mother, Carolyn, makes a surprise visit and meets Meredith for the first time. Meanwhile, Mark tries to hide his relationship with Lexie; William, the death row inmate, asks to donate his organs to Bailey's patient; and Owen and Cristina go on their first date.
Special Guest Stars: Tyne Daly as Carolyn Shepherd (Dr. Derek Shepherd's Mother) | Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Brandon Scott (2) as Intern Ryan | Ernie Grunwald as Gary Rubin (Brother of Patient Chuck Rubin) | Jason Kravits as Chuck Rubin (Patient: Bone Infection from Botched Leg Surgery) | Samantha Mathis as Melinda Prescott (Mother of Patient Jackson Prescott) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Eric Stoltz as William Dunn (Patient: Spinal Trauma, Death Row Inmate) | Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) |
Co-Guest Stars: Candice Afia as Intern Laura | Mark Saul as Intern Steve | Molly Kidder as Intern Megan | Gloria Garayua as Intern Graciella | Aaron Refvem as Jackson Prescott (Patient: Child, Bowel and Liver Failure)
Director: Jeannot Szwarc
Writer: Jenna Bans
Songs: Anya Marina -- All the Same to Me, Glass Pear -- Last Day of Your Life, Winterpills -- Take Away the Words, Johnathan Rice -- The Acrobat, Right Away, Great Captain! -- What a Pity

91 :05x13 - Stairway to Heaven

Jan/22/2009
Bailey becomes desperate as her patient's condition rapidly worsens, causing everyone to work to find the boy an organ donor before it's too late. Meanwhile, Mark finds himself in a compromising position and Crisitina avoids Owen.
Guest Stars: Amy Sloan as Kelly (Wife of Brain Dead Patient) | Brandon Scott (2) as Intern Ryan | Samantha Mathis as Melinda Prescott (Mother to Patient Jackson Prescott) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Eric Stoltz as William Dunn (Patient: Spinal Injury, Death Row Inmate) | Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Kevin McKidd as Dr. Owen Hunt (New Trauma Surgeon) | Jeffrey Dean Morgan as Denny Duquette |
Co-Guest Stars: Winston Story as Intern Leo | Joseph Williamson as Intern Pierce | Gloria Garayua as Intern Graciella | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Molly Kidder as Intern Megan | Mark Saul as Intern Steve | Moe Irvin as Nurse Tyler Christian | Aaron Refvem as Jackson Prescott (Patient: Organ Transplants)
Director: Allison Liddi
Writer: Mark Wilding
Songs: Emiliana Torrini -- Birds, Bon Iver -- Blindsided, Powderfinger -- Drifting Further Away

92 :05x14 - Beat Your Heart Out

Feb/05/2009
With the engagement ring taken care of, Derek ponders the perfect way to pop the question to Meredith. Meanwhile, Lexie demands that Mark go public with their relationship; and Bailey, happy with her work with recent patients, considers a new career direction.
Guest Stars: Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Mary McDonnell as Dr. Virginia Dixon (Heart Surgeon, Has Asperger Syndrome) | Brandon Scott (2) as Intern Ryan | Laura Allen as Beth Whitman (Ex-Fiancee of Dr. Owen Hunt) | Peter MacKenzie as Warren Kramer (Patient: Foreign Object in Rectum) | Ben Shenkman as Rob Harmon (Patient: Wife Ran Over Him With Car) | Jennifer Westfeldt as Jen Harmon (Patient: Wife of Rob Harmon, Pregnant, Seizures) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) |
Co-Guest Stars: Kate Anthony as Nurse Kate | Winston Story as Intern Leo | Joseph Williamson as Intern Pierce | Molly Kidder as Intern Megan | Mark Saul as Intern Steve | Jamey Dettman as Stacy Pollock (Patient: Young Girl, Heart Surgery) | Martha Boles as Lisa Pollock (Mother of Patient Stacy Pollock) | Eric Payne as Dan Pollock (Father of Patient Stacy Pollock) | Susan Merson as Lorraine (Patient: Clinic, Sore Throat, Blood Work)
Songs: Kate Havnevik -- Halo, Dido -- Never Want To Say It's Love, Bon Iver -- Re: Stacks, Nikka Costa -- Stuck to You, Trolle//siebenhaar -- These Streets, Panda Transport -- Transmission

93 :05x15 - Before and After

Feb/12/2009
Addison, Naomi and Sam bring Archer to Seattle Grace in order to have Derek and Mark work to save his life. Meanwhile, Izzie works on a medical game to help the interns.
Special Guest Stars: Taye Diggs as Dr. Sam Bennett (Cardiothoracic Surgeon, Friend of Addison) | Audra McDonald as Dr. Naomi Bennett (Reproductive Specialist and Archer's Girlfriend) | Kate Walsh as Dr. Addison Montgomery (Neonatal Surgeon and Derek's Ex-Wife) |
Guest Stars: Melissa George as Sadie Harris (New Intern, Old Friend of Meredith's) | Brandon Scott (2) as Intern Ryan | Steven W. Bailey as Joe (The Bartender at Emerald City Bar) | Sam Anderson as Michael Whitman (Patient: Colo-rectal Cancer) | Laura Allen as Beth Whitman (Ex-Fiancee of Dr. Owen Hunt) | Ben Shenkman as Rob Harmon (Patient: Run Over by Car) | Jennifer Westfeldt as Jen Harmon (Patient: Pregnant with Seizures and Anneurism) | Grant Show as Archer Forbes Montgomery (Patient: Brain Tumour, Addison's Brother) |
Co-Guest Stars: Kate Anthony as Nurse Kate | Joseph Williamson as Intern Pierce | Winston Story as Intern Leo | Molly Kidder as Intern Megan | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Gloria Garayua as Intern Graciella | Mark Saul as Intern Steve
Director: Daniel Attias
Songs: Keri Noble -- Emily, Liam Finn -- Gather to the Chapel, Slow Runner -- Happy Ending, Shontelle -- Roll It, Sara Bareilles -- Winter Song (featuring Ingrid Michaelson)

94 :05x16 - An Honest Mistake

Feb/19/2009
Derek's confidence is dashed as he squares off with Addison over a patient. Cristina begins to doubt the abilities of a surgeon after she messes up on a routine procedure. Meanwhile, Bailey, pursuing a fellowship in pediatrics, is appalled by the Chief's recommendation letter.
Special Guest Stars: Kate Walsh as Dr. Addison Montgomery (Neonatal Surgeon Visiting from Private Practice) |
Guest Stars: Ben Shenkman as Rob Harmon (Husband of Patient Jen Harmon) | Kathleen Early as Dr. Daisy Pepman (Dermatologist) | Louis Giambalvo as John Terzian (Patient: Complication From Surgery by Dr. Campbell) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Jennifer Westfeldt as Jen Harmon (Patient: Pregnant with Seizures and Anneurism) | Faye Dunaway as Dr. Margaret Campbell (General Surgeon, First Female Surgeon at Hospital) |
Co-Guest Stars: Susan Merson as Lorraine (Patient: Was Misdiagnosed in Clinic With Cancer) | Molly Kidder as Intern Megan | Winston Story as Intern Leo | Joy Osmanski as Intern Lucy | Mark Saul as Intern Steve | Gloria Garayua as Intern Graciella | Brandon Scott (2) as Intern Ryan
Director: Randall Zisk
Writer: Peter Nowalk
Songs: Dash & Will -- Error, Error, Calahan -- Like a Ghost, Snow Patrol -- The Planets Bend Between Us, Matt Hires -- Turn the Page, Little Dragon -- Twice

95 :05x17 - I Will Follow You Into the Dark

Mar/12/2009
When Derek learns that more of his patients have died than survived, he decides to quit despite Meredith standing by him. Meanwhile, Bailey and the Chief continue to fail to see eye-to-eye on the fellowship until Adele steps in. Elsewhere, Izzie's interns discover dire news in regards to "patient x," unaware it's Izzie.
Guest Stars: Loretta Devine as Adele Webber (The Chief's Wife) | Brandon Scott (2) as Intern Ryan | Susane Lee (1) as Beth Dearborn (Patient: Grand Mal Seizures) | Erin Cahill as Meg Shelley (Patient: Surgery for Gastric Cancer) | Wendy Hoopes as Tricia Shelley (Patient:Surgery for Gastric Cancer) | Michael Rady as Mike Shelley (Patient: Surgery for Gastric Cancer) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) |
Co-Guest Stars: Nicole Cummins as Paramedic | Winston Story as Intern Leo | Joseph Williamson as Intern Pierce | Molly Kidder as Intern Megan | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candice Afia as Intern Laura | Gloria Garayua as Intern Graciella | Mark Saul as Intern Steve | Marcus McGee as Boy Band Geek (Band Mate of Patient Beth Dearborn) | B.K. Cannon as Girl Band Geek (Band Mate of Patient Beth Dearborn) | Phil Abrams as Dr. Jim Nelson (Neurosurgeon)
Director: Rob Corn
Writer: Jenna Bans
Songs: Piers Faccini -- A Storm is Going to Come, Rachael Yamagata -- Duet, Metric -- Front Row, Shady Bard -- Treeology

96 :05x18 - Stand By Me

Mar/19/2009
As Izzie continues to hide her medical secret, the residents all try to convince Derek to come back to work but fail at doing so. Meanwhile, Mark attempts a radical face transplant surgery; and Cristina is awarded a solo surgery, but is preoccupied by Izzie's condition.
Guest Stars: Larry Sullivan as David Young (Patient: Face Transplant Nicknamed "Blowhole") | Emily Kuroda as Kendall Sully (Patient: Hernia Repair) | Brandon Scott (2) as Intern Ryan |
Co-Guest Stars: Martin Yu as Anesthesiologist | Winston Story as Intern Leo | Joseph Williamson as Intern Pierce | Molly Kidder as Intern Megan | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Candace Brown as Milo (Friend of Patient David Young) | Mark Saul as Intern Steve | Michael Merton as Dexter (Friend of Patient David Young) | Greta Sesheta as Shayna (Friend of Patient David Young) | Darcy Martin as Sharon | Candice Afia as Intern Laura
Director: Jessica Yu
Writer: Zoanne Clack
Songs: Royal Wood -- A Mirror Without, Great Northern -- Driveway, Common -- Everywhere (featuring Martina Topley-Bird)

97 :05x19 - Elevator Love Letter

Mar/26/2009
Tensions are high as Derek returns to Seattle Grace to perform his first surgery following his breakdown. Meanwhile, everyone turns their attention to Izzie, who must undergo surgery for her condition; and Owen suffers from another PTSD episode that injures Cristina, putting their relationship at risk.
Guest Stars: Brandon Scott (2) as Intern Ryan | Todd Waring as Tobin (Family Member of Dying Elderly Patient) | Molly Hagan as Jackie (Family Member of Dying Elderly Patient) | Kimberly Elise as Dr. Swender (Surgical Oncologist on Izzie's Case) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) |
Co-Guest Stars: Molly Kidder as Intern Megan | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Gloria Garayua as Intern Graciella | Zibby Allen as Nurse | Winston Story as Intern Leo | Candice Afia as Intern Laura | Joseph Williamson as Intern Pierce | Mark Saul as Intern Steve | Tim Maculan as Luke (Family Member of Dying Elderly Patient)
Director: Edward Ornelas
Writer: Stacy McKee
Songs: Gomez -- Little Pieces, Ben Lee -- Rise Up, The Cinematic Orchestra -- That Home, Sanders Bohlke -- The Weight of Us, O+S -- We Do What We Want To, Peter Broderick -- With the Notes in My Ears

98 :05x20 - Sweet Surrender

Apr/23/2009
As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding.
Guest Stars: Amy Madigan as Dr. Katharine Wyatt (Psychiatric Doctor) | Hector Elizondo as Mr. Carlos Torres (Dr. Callie Torres' Father) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Kimberly Elise as Dr. Swender (Surgical Oncologist on Izzie's Case) | Elden Henson as Matt Smithson (Father of Patient Jessica Smithson) | José Zúñiga as Anthony Meloy (Patient: Hit By A Car) | Obba Babatundé as David Gates (Patient: Car Accident) |
Co-Guest Stars: Mac Brandt as Paramedic #2 | Nicole Cummins as Paramedic #1 | Moe Irvin as Nurse Tyler Christian | Regi Davis as Dr. Kevin Fisher (Doctor George Called For Psych Consult) | Mary-Charles Jones as Jessica Smithson (Patient: Young Girl With Tay-Sachs) | Carlease Burke as Mrs. Gates (Wife of Patient David Gates)
Director: Tony Phelan
Songs: The Rescues -- Break Me Out, Shady Bard -- Summer Came When We Were Falling Out, Jont -- Sweetheart, The Mostar Diving Club -- Vagabonds and Clowns

99 :05x21 - No Good at Saying Sorry (One More Chance)

Apr/30/2009
As Meredith and Derek continue to prepare for their wedding day, Izzie receives a surprise visit from her mother, and a person from Meredith and Lexie's past arrives at Seattle Grace.
Guest Stars: Nina Siemaszko as Kate Carlson (Wife of Patient with Gunshot Wounds) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Sharon Lawrence as Robbie Stevens (Izzie's Mother) | Megan Henning as Willow Zelman (Patient: Fell Out of Tree and Broke Limbs) | Kellie Martin as Julie Zelman (Sister of Patient Willow Zelman) | Jeff Perry as Thatcher Grey (Meredith and Lexie's Father) |
Co-Guest Stars: Destiny Whitlock as Maddy Carlson (Daughter of Patient with Gunshot Wounds) | Brooke Blanchard as Jill the Paramedic
Director: Tom Verica
Songs: Emilie Mover -- Brand New, Brett Dennen -- So Far from Me, The Rescues -- Stay Over, All Thieves -- Turn and Turn Again, The Hard Lessons -- Wedding Ring

100 :05x22 - What a Difference a Day Makes

May/07/2009
As Meredith, Derek and their friends and family gather for their wedding, a group of several college students are admitted to the E.R. following a car crash.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Amy Gumenick as Becca Wells (Patient: Car Accident Victim and Valedictorian) | Roberto Urbina as Jordan (Patient: Car Accident) |
Co-Guest Stars: Joseph Williamson as Intern Pierce | Payton Silver as Dr. Knox (Anesthesiologist) | Wayne Lopez as Paramedic #1 | Shi Ne Nielson as Paramedic #2 | Mac Brandt as Paramedic #3 | Tim Chiou as Paramedic #4 | Winston Story as Intern Leo | Tymberlee Hill as Intern Claire | Amrapali Ambegaokar as Intern Dani | Robin Gwynne as Becca's Mom (Mother of Patient Becca) | Trent Gill as David (Patient: Car Accident) | Mark Saul as Intern Steve | Molly Kidder as Intern Megan | Candice Afia as Intern Laura | Mickey Maxwell as Minister
Director: Rob Corn
Songs: Au Revoir Simone -- Another Likely Story, Matthew Mayfield -- First in Line, Ingrid Michaelson -- Turn to Stone

101 :05x23 - Here's to the Future (1)

May/14/2009
After spending time with a fellow cancer patient, Izzie begins to question whether or not to undergo a risky procedure. Meanwhile, Mark considers taking his relationship with Lexie to the next level; and after helping a patient, Owen begins to rethink his position at Seattle Grace.
Special Guest Stars: Jeffrey Dean Morgan as Denny Duquette |
Guest Stars: Kimberly Elise as Dr. Swender (Surgical Oncologist on Izzie's Case) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Liza Weil as Alison Clark (Patient: Woman With Cancer and Friend of Izzie's) | Zach Gilford as Charlie Lowell (Patient: Iraq Soldier, Leg Amputation) | Debra Mooney as Mrs. Hunt (Dr. Owen Hunt's Mother) |
Co-Guest Stars: Brock Cuchna as Recruiting Clerk | J.F. Davis as Recruiting Officer | Jon Rowland as Alison's Boyfriend | Chelsea Taylor as Alison's Mother | Webster Williams as Alison's Father
Director: Bill D'Elia
Songs: Joy Williams -- Charmed Life, Sugarplum Fairies -- Hold on to Me, -- Where the Road Meets the Sun

102 :05x24 - Now or Never (2)

May/14/2009
George gives Bailey news that shocks the entire hospital as everyone awaits for Izzie to recover from surgery. Meanwhile, Bailey is accepted into the pediatric fellowship program; and Seattle Grace comes together to help save a traffic accident victim.
Guest Stars: Shannon Lucio as Amanda (Patient: Almost Hit By A Bus) | Jessica Capshaw as Dr. Arizona Robbins (Pediatric Surgeon) | Kimberly Elise as Dr. Swender (Surgical Oncologist on Izzie's Case) |
Co-Guest Stars: John Cappon as Paramedic #1 | Brooke Blanchard as Paramedic #2
Director: Rob Corn
Songs: Ingrid Michaelson -- All Love, Hollywood, Mon Amour -- Flashdance...What a Feeling (featuring Yael Naim), Greg Laswell -- Off I Go, Missy Higgins -- The Battle
Classification: Scripted
Genre: Drama | Medical
Status: Returning Series
Network: ABC ( USA)
Airs: Thursdays at 09:00 pm
Runtime: 60 Minutes
Premiere: March 27, 2005
Episode Order: 24
This guide is currently edited by:
harrisr (Challenge)

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