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Grey's Anatomy: What a Difference a Day Makes

As Meredith, Derek and their friends and family gather for their wedding, a group of several college students are admitted to the E.R. following a car crash.

Episode Info


Episode number: 5x22
Production Number: 522
Airdate: Thursday May 07th, 2009

Director: Rob Corn
Writer: Shonda Rhimes

Alternate Airdates:

FI (Nelonen) May 27, 2009
UK (sky LIVING) Jun 18, 2009
NL (Net 5) Nov 02, 2009

Trailer


 
Flash
Special Guest Stars
Jeffrey Dean MorganJeffrey Dean Morgan
As Denny Duquette
Recurring

Guest Stars
Jessica CapshawJessica Capshaw
As Dr. Arizona Robbins (Pediatric Surgeon)
Recurring
Amy GumenickAmy Gumenick
As Becca Wells (Patient: Car Accident Victim and Valedictorian)
Roberto UrbinaRoberto Urbina
As Jordan (Patient: Car Accident)

Co-Guest Stars
Amrapali AmbegaokarAmrapali Ambegaokar
As Intern Dani
Recurring
Candice AfiaCandice Afia
As Intern Laura
Recurring
Joseph WilliamsonJoseph Williamson
As Intern Pierce
Recurring
Mac BrandtMac Brandt
As Paramedic #3
Recurring
Mark SaulMark Saul
As Intern Steve
Recurring
Molly KidderMolly Kidder
As Intern Megan
Recurring
Payton SilverPayton Silver
As Dr. Knox (Anesthesiologist)
Recurring
Shi Ne NielsonShi Ne Nielson
As Paramedic #2
Recurring
Tim ChiouTim Chiou
As Paramedic #4
Recurring
Tymberlee HillTymberlee Hill
As Intern Claire
Recurring
Wayne LopezWayne Lopez
As Paramedic #1
Recurring
Winston StoryWinston Story
As Intern Leo
Recurring
Mickey MaxwellMickey Maxwell
As Minister
Robin GwynneRobin Gwynne
As Becca's Mom (Mother of Patient Becca)
Trent GillTrent Gill
As David (Patient: Car Accident)
Main Cast
Ellen PompeoEllen Pompeo
As Dr. Meredith Grey
Justin ChambersJustin Chambers
As Dr. Alex Karev
Patrick DempseyPatrick Dempsey
As Dr. Derek Shepherd
Chandra WilsonChandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.James Pickens, Jr.
As Dr. Richard Webber
Sara RamirezSara Ramirez
As Dr. Calliope "Callie" Torres
Kevin McKiddKevin McKidd
As Dr. Owen Hunt
Chyler LeighChyler Leigh
As Dr. Lexie Grey
Eric DaneEric Dane
As Dr. Mark Sloan
T.R. KnightT.R. Knight
As Dr. George O'Malley
Sandra OhSandra Oh
As Dr. Cristina Yang
Katherine HeiglKatherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 15.33 Million Viewers

Voiceover: The opening and closing voiceover's are done by Izzie this time instead of Meredith.

Timeline: This was the 100th episode of Grey's Anatomy.

Trivia: Alex's full name is Alexander Michael Karev. Izzie's full name is Isobel Katherine Stevens.



Music
ArtistSong TitlePlayed When
Au Revoir SimoneAnother Likely StoryCallie and Arizona Talk, Meredith Finishes Surgery
Ingrid MichaelsonTurn to StoneThe Bride Getting Ready, Plays Almost to End
Matthew MayfieldFirst in LineIzzie Tries to See "Denny", Patient Recites Speech


Episode Quotes
Izzie:(opening voiceover)You never know the biggest day of your life is the biggest. The days you think are going to be big ones, they're never as big as you make them out to be in your head. It's the regular days. The ones that start out normal, those are the days that end up being the biggest. And today was the wedding. It was beautiful, perfect.

Rebecca(the speech): Today is the day my life begins. Today I become a citizen of the world. today I become a grown up. Today I become accountable to someone other than myself and my parents, accountable for more than my grades. Today I become accountable to the world, to the future, to all the possibilities that life has to offer. starting today, my job is to show up wide eyed and willing and ready, for what? I don't know. For anything, for everything. To take on life. To take on love. To take on the responsibility and possibility. Today my friends our lives begins. and I for one, can't wait.

Alex(his vows): Today is the day my life begins. All my life i've been just me, just a smart mouth kid, today I become a man. Today I become a husband. Today I become accountable to someone other than myself. Today I become accountable to you, to our future, to all the possibilities that a marriage has to offer. Together no matter what happens, I'll be ready. For anything, for everything. To take on life. To take on love. to take on possibility and responsibility. Today Izzie Stevens, our life together begins. And I for one, can't wait.
Izzie: I love you.

Denny Duquette: I bet you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you you don't need it, you look gorgeous without it.
Denny Duquette: He's right.
Izzie: Go away now. Go away I wanna be alone with my husband.
Alex: My wife is hot.

Izzie: (closing voiceover)You never know the biggest day of your life is the biggest. Not until it's happening. You never recognize the biggest day of your life, not until you're in it, in the middle of it. The day you get your heart broken. The day you realize there is not enough time because you want to live forever. Those are the biggest days. The perfect days.

Izzie:(opening voiceover)You never know the biggest day of your life is the biggest. The days you think are going to be big ones, they're never as big as you make them out to be in your head. It's the regular days. The ones that start out normal, those are the days that end up being the biggest. And today was the wedding. It was beautiful, perfect.

Rebecca(the speech): Today is the day my life begins. Today I become a citizen of the world. today I become a grown up. Today I become accountable to someone other than myself and my parents, accountable for more than my grades. Today I become accountable to the world, to the future, to all the possibilities that life has to offer. starting today, my job is to show up wide eyed and willing and ready, for what? I don't know. For anything, for everything. To take on life. To take on love. To take on the responsibility and possibility. Today my friends our lives begins. and I for one, can't wait.

Alex(his vows): Today is the day my life begins. All my life i've been just me, just a smart mouth kid, today I become a man. Today I become a husband. Today I become accountable to someone other than myself. Today I become accountable to you, to our future, to all the possibilities that a marriage has to offer. Together no matter what happens, I'll be ready. For anything, for everything. To take on life. To take on love. to take on possibility and responsibility. Today Izzie Stevens, our life together begins. And I for one, can't wait.
Izzie: I love you.
(Start kissing)
Priest: Not yet.
Alex: Hurry up.
Priest: I now pronounce you husband and wife.

Denny Duquette: I bet you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you you don't need it, you look gorgeous without it.
Denny Duquette: He's right.
Izzie: Go away now. Go away I wanna be alone with my husband.
Alex: My wife is hot.

Izzie:(closing voiceover)You never know the biggest day of your life is the biggest. Not until it's happening. You never recognize the biggest day of your life, not until you're in it, in the middle of it. The day you get your heart broken. The day you realize there is not enough time because you want to live forever. Those are the biggest days. The perfect days.



Episode Goofs
Continuity:

When Meredith approaches Alex outside with the idea of marrying Izzie, he is clean shaven. Later, when Alex goes into Izzie's room in his groom's outfit he has not shaved yet.




Cultural References
Episode Title: What a Difference a Day Makes

"What a Difference a Day Makes" is the title of a song by Dinah Washington.

Bridezillas: Mentioned in dialogue between Christina and Meredith in reference to Izzie's wedding planning.



Episode References
Season 5, Episode 7: Izzie begins having hallucinations of Denny again. Denny as a hallucination originally began in 5x7 "Rise Up".



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