Login or register  
TV
<-- Previous EpisodeNext Episode -->

Grey's Anatomy: What a Difference a Day Makes

As Meredith, Derek and their friends and family gather for their wedding, a group of several college students are admitted to the E.R. following a car crash.


Episode Info


Episode number: 5x22
Production Number: 522
Airdate: Thursday May 07th, 2009

Director: Rob Corn
Writer: Shonda Rhimes

Alternate Airdates:

FI (Nelonen) May 27, 2009
UK (sky LIVING) Jun 18, 2009
NL (Net 5) Nov 02, 2009

  • Currently 9/10
9/10 (23 Votes cast)

Trailer


 
Flash
Special Guest Stars
Jeffrey Dean Morgan
As Denny Duquette
Recurring

Guest Stars
Jessica Capshaw
As Dr. Arizona Robbins (Pediatric Surgeon)
Recurring
Amy Gumenick
As Becca Wells (Patient: Car Accident Victim and Valedictorian)
Roberto Urbina
As Jordan (Patient: Car Accident)

Co-Guest Stars
Amrapali Ambegaokar
As Intern Dani
Recurring
Candice Afia
As Intern Laura
Recurring
Joseph Williamson
As Intern Pierce
Recurring
Mac Brandt
As Paramedic #3
Recurring
Mark Saul
As Intern Steve
Recurring
Molly Kidder
As Intern Megan
Recurring
Payton Silver
As Dr. Knox (Anesthesiologist)
Recurring
Shi Ne Nielson
As Paramedic #2
Recurring
Tim Chiou
As Paramedic #4
Recurring
Tymberlee Hill
As Intern Claire
Recurring
Wayne Lopez
As Paramedic #1
Recurring
Winston Story
As Intern Leo
Recurring
Mickey Maxwell
As Minister
Robin Gwynne
As Becca's Mom (Mother of Patient Becca)
Trent Gill
As David (Patient: Car Accident)
Main Cast
Ellen Pompeo
As Dr. Meredith Grey
Justin Chambers
As Dr. Alex Karev
Patrick Dempsey
As Dr. Derek Shepherd
Chandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.
As Dr. Richard Webber
Sara Ramirez
As Dr. Calliope "Callie" Torres
Kevin McKidd
As Dr. Owen Hunt
Chyler Leigh
As Dr. Lexie Grey
Eric Dane
As Dr. Mark Sloan
T.R. Knight
As Dr. George O'Malley
Sandra Oh
As Dr. Cristina Yang
Katherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 15.33 Million Viewers

Voiceover: The opening and closing voiceover's are done by Izzie this time instead of Meredith.

Timeline: This was the 100th episode of Grey's Anatomy.

Trivia: Alex's full name is Alexander Michael Karev. Izzie's full name is Isobel Katherine Stevens.



Music
ArtistSong TitlePlayed When
Au Revoir SimoneAnother Likely StoryCallie and Arizona Talk, Meredith Finishes Surgery
Ingrid MichaelsonTurn to StoneThe Bride Getting Ready, Plays Almost to End
Matthew MayfieldFirst in LineIzzie Tries to See "Denny", Patient Recites Speech


Episode Quotes
Izzie:(opening voiceover)You never know the biggest day of your life is the biggest. The days you think are going to be big ones, they're never as big as you make them out to be in your head. It's the regular days. The ones that start out normal, those are the days that end up being the biggest. And today was the wedding. It was beautiful, perfect.

Rebecca(the speech): Today is the day my life begins. Today I become a citizen of the world. today I become a grown up. Today I become accountable to someone other than myself and my parents, accountable for more than my grades. Today I become accountable to the world, to the future, to all the possibilities that life has to offer. starting today, my job is to show up wide eyed and willing and ready, for what? I don't know. For anything, for everything. To take on life. To take on love. To take on the responsibility and possibility. Today my friends our lives begins. and I for one, can't wait.

Alex(his vows): Today is the day my life begins. All my life i've been just me, just a smart mouth kid, today I become a man. Today I become a husband. Today I become accountable to someone other than myself. Today I become accountable to you, to our future, to all the possibilities that a marriage has to offer. Together no matter what happens, I'll be ready. For anything, for everything. To take on life. To take on love. to take on possibility and responsibility. Today Izzie Stevens, our life together begins. And I for one, can't wait.
Izzie: I love you.

Denny Duquette: I bet you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you you don't need it, you look gorgeous without it.
Denny Duquette: He's right.
Izzie: Go away now. Go away I wanna be alone with my husband.
Alex: My wife is hot.

Izzie: (closing voiceover)You never know the biggest day of your life is the biggest. Not until it's happening. You never recognize the biggest day of your life, not until you're in it, in the middle of it. The day you get your heart broken. The day you realize there is not enough time because you want to live forever. Those are the biggest days. The perfect days.

Izzie:(opening voiceover)You never know the biggest day of your life is the biggest. The days you think are going to be big ones, they're never as big as you make them out to be in your head. It's the regular days. The ones that start out normal, those are the days that end up being the biggest. And today was the wedding. It was beautiful, perfect.

Rebecca(the speech): Today is the day my life begins. Today I become a citizen of the world. today I become a grown up. Today I become accountable to someone other than myself and my parents, accountable for more than my grades. Today I become accountable to the world, to the future, to all the possibilities that life has to offer. starting today, my job is to show up wide eyed and willing and ready, for what? I don't know. For anything, for everything. To take on life. To take on love. To take on the responsibility and possibility. Today my friends our lives begins. and I for one, can't wait.

Alex(his vows): Today is the day my life begins. All my life i've been just me, just a smart mouth kid, today I become a man. Today I become a husband. Today I become accountable to someone other than myself. Today I become accountable to you, to our future, to all the possibilities that a marriage has to offer. Together no matter what happens, I'll be ready. For anything, for everything. To take on life. To take on love. to take on possibility and responsibility. Today Izzie Stevens, our life together begins. And I for one, can't wait.
Izzie: I love you.
(Start kissing)
Priest: Not yet.
Alex: Hurry up.
Priest: I now pronounce you husband and wife.

Denny Duquette: I bet you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you you don't need it, you look gorgeous without it.
Denny Duquette: He's right.
Izzie: Go away now. Go away I wanna be alone with my husband.
Alex: My wife is hot.

Izzie:(closing voiceover)You never know the biggest day of your life is the biggest. Not until it's happening. You never recognize the biggest day of your life, not until you're in it, in the middle of it. The day you get your heart broken. The day you realize there is not enough time because you want to live forever. Those are the biggest days. The perfect days.



Episode Goofs
Continuity:

When Meredith approaches Alex outside with the idea of marrying Izzie, he is clean shaven. Later, when Alex goes into Izzie's room in his groom's outfit he has not shaved yet.




Cultural References
Episode Title: What a Difference a Day Makes

"What a Difference a Day Makes" is the title of a song by Dinah Washington.

Bridezillas: Mentioned in dialogue between Christina and Meredith in reference to Izzie's wedding planning.



Episode References
Season 5, Episode 7: Izzie begins having hallucinations of Denny again. Denny as a hallucination originally began in 5x7 "Rise Up".



Missing Information
Click here to add Analysis
Warning: Grey's Anatomy season 5 episode 22 guide may contain spoilers
Recent news

Keith Allen, Daniel Rigby and Michael Socha to star in new Dave Comedy 'Undercover'

Today UKTV network Dave have announced a exciting new comedy commission..

BBC Commissions A Second Series of 'In the Club'

Kay Mellor’s BBC One drama, ‘In the Club’ has been commissioned for..

Skyler Samuels Books Major Role on 'American Horror Story'

‘American Horror Story’ is adding to its ranks for the fourth..