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Episode number: 6x22 Airdate: Thursday May 13th, 2010 Alternate Airdates:
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| Artist | Song Title | Played When |
| Andrew Belle | Open Your Eyes | Bailey Explains No Time for Games, Closing Scenes |
| Goldfrapp | Shiny and Warm | Awkward Moment in Surgery, Lunch Scene |
| Keane | My Shadow | Elderly Patient Apologizes, Burn Patient's Surgery |
| Kerry Leatham | Do You Fancy Me | Opening Scenes, Seattle, Derek's Party |
| Richard Walters | American Stitches | Friend Comforts Burn Patient, Patient Tells Story |
| • Creator | Shonda Rhimes |
| • Executive Producer | Betsy Beers  | Allan Heinberg  | Mark Wilding  | Rob Corn  | Mark Gordon (4)  | Shonda Rhimes  | Krista Vernoff |
| • Co-Executive Producer | Jenna Bans  | Tony Phelan  | Joan Rater |
| • Supervising Producer | Stacy McKee  | Zoanne Clack |
| • Producer | Linda Klein  | Tammy Ann Casper  | Jeff Rafner |
| • Consulting Producer | Debora Cahn (1) |
| • Production Designer | Donald Lee Harris (1) |
| • Editor | Joe Mitacek |
| • Director of Photography | Herbert Davis (1) |