Meredith (opening voiceover): Fresh starts thanks to the calendar they happen every year --just set your watch to January, our reward for surviving the holiday season is a new year. Bringing on the great tradition of new years resolutions, put your past behind you and start over. It's hard to resist the chance of a new beginning, a chance to put the problems of last year to bed.
George: We need to talk about the dog.
Izzie: That's not a dog. It's a hyena escaped from the zoo, and dressed in dog clothing.
Richard: Cranky nurses don't do us any good.
Izzie: (to Alex) Oh, well, maybe you can cheer them up.
George: ... well, then, why?
Bex: I'm as flat as a board. I took like five of those pills a day.
George: (looks confused)
Bex: Boobs, dude!
Derek: (to Addison) There is a land called Passive Agressiva, and you are their queen.
George: In high school I was secretary and treasurer of the Dungeons & Dragons club.
Bex: Oh man..
Meredith: I've moved on. So don't give me that look.
Derek: What look?
Meredith: That look. Our look. I'm over you.
Derek: I'm over you too.
Meredith: You are?
Meredith: Well, I am... Over you.
Derek: I'm over you too.
Meredith: You just said-- shut up.
George: Your lab work...showed...have you been taking birth control pills?
Bex: If you tell my mom and dad they'll-
George: I won't! I won't--I just need to know...why? Do you have a boyfriend?
Bex: Like anyone would want to have sex with me--
Bex: I'm as flat as a board. I took like five of those pills a day and nothing's different. Boobs, dude.
George: You...were trying to make your breasts grow.
Bex: I wanted to be normal for once in my life.
Cristina: I wasn't gonna have it. The baby. And you don't get to be mad about that. We barely knew each other. I was an intern, and there was no way that I could have even...
Burke: I'm not mad.
Cristina: You're not?
Burke: No. I just wanted to know. I want to know things.
Bailey: I hope seeing you here means that they finally found you a heart.
Denny: No offence doctor but I'm not a big fan of hospitals. It takes something pretty special to get me in here.
Bailey (to Izzie): What do we know about Mr Duquette?
Denny: Capricorn, single, loves to travel and cook.
Bailey: Denny be quiet. Let her show off.
George: Hey, aren't you supposed to be having free time?
Meredith: Oh, I did 5 loads of laundry. Cut my split ends, studied, cleaned out the fridge. Free time sucks.
George: When would have been the best time to hear about your boyfriend's wife?
Meredith (gives him a look): Okay, are you mad at me or something?
George: No! No. Sorry. It's just I have this patient and I get that there's a right and a wrong time to hear big news but wouldn't you rather no sooner than later? I mean just so you could move forward one way or the other. It's a fresh start, right?
Meredith (closing voiceover): Who gets to determine when the old ends and the new begins? It's not on the calendar, it's not a birthday, it's not a new year, it's an event --big or small, something that changes us, ideally it gives us hope, a new way of living and looking at the world, letting go of old habits, old memories. What's important is that we never stop believing we can have a new beginning, but it's also important to remember amid all the crap are a few things really worth holding on to.