Ratings: 24.36 Million Viewers
Awards and Nominations: This episode was nominated for the 2006 Emmy Award for Outstanding Prosthetic Makeup For A Series, Miniseries, Movie, or a Special.
Nicknames: Following the trend of "McLabeling", Dr. Mark Sloan is named "McSteamy" by the interns.
Casting: This is the first appearance of Jeff Perry (Thatcher Grey).
Trivia: At Joe's, Mark orders a double scotch single malt. That is the exact same drink Derek always orders.
Meredith (opening voiceover): After careful consideration and many sleepless nights, here's what I've decided. There's no such thing as a grown-up. We move on, we move out, we move away from our families and form our own. But the basic insecurities, the basic fears and all those old wounds just grow up with us. And just when we think life and circumstances have forced us truly to become an adult, your mother says something like that. Or worse, something like that. We get bigger, we get taller, we get older. But, for the most part, we're still a bunch of kids, running around the playground, trying desperately to fit in.
Cristina: What's wrong with you?
Meredith: My mommy's a filthy whore.
Izzie: (to Alex) You have dirty in your eyes.
Addison: Put the ice back on your hand.
Derek: My hand is fine.
Richard: Put the damn ice on your two-million-dollar-a-year-hand.
Dr. Mark Sloan: (to Meredith) You know, it's funny. Derek walks in on me naked with his wife, actually in the throes, then he just turns around and walks away. But he sees me as much as talking to you, and I'm on the ground bleeding. Interesting, don't you think?
Meredith: McSexy wants an x-ray to check for fractures.
Cristina & Meredith: No.
Cristina: Ah, there it is.
George: Now, I'll think I'll just be choking back some.. McVomit.
Izzie: You know, how when you don't have sex for a while, you sort of forget how good it is, and don't really need it as much?
George: Yeah, that doesn't happen to guys.
Izzie: It's like a beast. A beast that was asleep for a long long time, and now the beast is wide awake, and it wants to be fed. And the food that Alex gave it was.. good food, George.
Preston: I am Preston Burke. A widely-renowned cardio-thoracic surgeon. I am a professional, and more than that, I am a good and kind person. I am a person who cleans up behind himself, I am a person that cooks well, and you, you are an unbelievable slob, an angry intern. I am Preston Burke. And you are the most competitive, the most guarded, stubborn, most challenging person that I have ever met. And I love you. What the hell is the matter with you that you won't just let me?
Cristina: I gave up my apartment 20 minutes ago.
Preston: Well, all right then.
Mark: You look sad.
Meredith: I just saw my father for the first time in 20 years.
Mark: How'd that go?
Meredith: Could've gone better? (pauses) What're you still doing here?
Mark: I'm hoping Addison shows up.
Meredith: Are you still in love with her?!
Mark: You're still in love with him!
Meredith: She won't show, you know.
Meredith: He's not the kind of guy you leave if you can help it.
Mark: What if you're wrong? What if just this once ... life comes down on the side of the dirty mistresses?
George: How do I look today? Would you say that I looked nice?
Izzie: You could use a little bit more lip gloss, but, yes you're very pretty.
George: Aw, you're mean.
Izzie: I'm just kidding, you look fine.
George: Seriously, how's my breath?
Izzie: George, would you just talk to her?
Cristina (about Addison): I don't get what McDreamy and McSteamy see in her.
Alex: Cause she's McHot.
George: McYeah she is.
Meredith (closing voiceover): We grow bigger and taller, but we never actually grow up. I've heard that it's possible to grow up, I've just never met anyone who's actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don't go our way. We whisper secrets with our best friends in the dark. We look for comfort where we can find it. And we hope; against all logic, against all experience. Like children, we never give up hope.