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A horrific ferry boat accident challenges the interns, as well as the rest of the hospital staff, both physically and mentally as they all near their breaking point. Chief Webber has to assemble and send out a team to the location of the accident to help save the few lives that were spared. On location, Alex tends to a woman who was crushed by a cement pylon. Meanwhile, Meredith looks out for a lost young girl and George searches frantically for a woman's young son.
Ratings: 25.20 Million Viewers
Filming: A majority of the ferry boat accident scenes were not filmed in Seattle. Producers and writers visited the real Coleman Dock, where the accident was said to have happened, and used pictures of the area to replicate the scene while filming in the Los Angeles area.
Trivia: During the episode, Addison mentions dyeing her red hair blond. In real life, Kate Walsh is naturally blond and often dyes her hair red for roles, including her role as Addison on Grey's Anatomy.
Meredith: (opening voiceover) Disappearances happen in science. Disease can suddenly fade away, tumours go missing, we open someone up to discover the cancer is gone. It's unexplained, it's rare, but it happens. We call it misdiagnosis, say we never saw it in the first place; any explanation but the truth that life is full of vanishing acts. If something that we didn't know we had disappears, do we miss it?
Alex: Where we going?
Bailey: We’ll know when we get there.
Izzie: What kind of situation? Fire? Flood? Volcano? 'Cause I’m not really dressed for a volcano.
Izzie: Sorry, that was inappropriate. Sorry.
Richard: What's the news?
Mark: Shepard and Grey are on the rocks, Burke and Yang got engaged. You need highlights in your hair. That's why it looks so odd. I'm gonna go save lives.
Meredith: I'm a surgeon. I do the rescuing. You are not my knight in shining whatever.
Derek: So we're gonna fight because I pulled you out of the tub.
Meredith: You have a place. You could sleep at it. And then you don't have to pull me out of the bathtub. You're everywhere, all the time, saying things.
Derek: This is the happy ever after part. And in the happily ever after, the guy is there all the time, saying things and the girls love it!
Meredith: Go to work, I'll see you there.
Derek: And just for the record? I am your knight in shining whatever.
Meredith: I did not try to drown myself in the bathtub.
Izzie: Hey, I ate everything out of the fridge last night. Everything. Including a tub of butter. There's no judgment here.
Derek: It just doesn't make sense. Ferry boats don't get in accidents. They're safe, they're reliable. The moment you take one for granted along comes a container ship and boom. I have a thing for ferry boats.
Cristina: Meredith, I have a thing... News.
Meredith: You're not pregnant again, are you? Cause I can't handle the extra months of bitchiness.
Episode Title: Walk On Water
"Walk On Water" is the title of a song recorded by several artists including Aerosmith, Ozzy Osbourne, and Eddie Money.