This episode was previously titled "Ain't Nothing Like The Real Thing".

Ratings: 20.9 million viewers

Meredith: (opening voiceover) A patient’s history is as important as their symptoms. It’s what helps us decide if heartburn’s a heart attack, if a headache’s a tumor. Sometimes patients will try to rewrite their own history. They’ll claim they don’t smoke, or forget to mention certain drugs. Which, in surgery, can be the kiss of death. We can ignore it all we want, but eventually it always comes back to haunt us.

Meredith: (closing voiceover) Our history resurfaces, time after time after time.
Mark: Not just surgery, but chief of surgery.
Woman: Really?
Webber: Um, well, not for much longer.
Mark: I’m gonna go, over there. Hold down the fort, Chief.
Webber: So, um…you come here often?
Woman: Oh, sometimes. It’s on my way home from bio class. (Webber chokes)
Addison: Excuse me. Is this seat taken?
Webber: No. (to the woman) Um, it was nice talking to you.
Woman: You too.
Webber: The last time I tried to pick up a woman I had a Harvey Wallbanger in one hand and an afro pick in the other.
Addison: Oh, Richard.
Webber: Well, you think about it. I mean, when you’re married you like to think you still have game.
Addison: Practice on me.
Webber: I’m sorry?
Addison: Mark’s right. I mean, he’s wrong about so many things, but he is right about this. You need to get back out there. So, practice.
Webber: Addison, I wouldn’t know where to start.
Addison: Ask me to dance.
Webber: Well, there’s no dance floor.
Addison: So? Ask me anyway. (they dance)
Meredith: (closing voiceover) So we have to remember: sometimes the most important history is the history you are making today.

Meredith: (about the groceries) This all you?
Susan: I just picked up some things to restock your fridge.
Meredith: Well, you bought groceries last week.
Derek: Yeah you have to do it every week, if you want more.

Burke: What was that?
Cristina: You’re gonna have to put up with me being nice and sweet for a little while.
Burke: That’ll be a nice change of pace.
Cristina: Shut up.
Burke: That’s more like it.

Bailey: (to Izzie) When you see her, you’ll know what to do. It must be nice to know she has parents like this, that fight for her, think about what she wants, tryin’ to make her happy, like you would. Doesn’t mean you don’t want that girl to want you.

Izzie: Hannah. An eleven year old girl. That’s the private matter. She’s mine. (George give Izzie a look) Don’t. Don’t look at me. My mother wanted me to keep her, but I knew, even at 16 I knew, that baby deserved better than life at Taylor’s Trailer Park. And now she’s here, and she may be dying and she doesn’t want to meet me. I didn’t think I really cared when she said no. How ‘bout that? I can say Hail Mary’s until … until I turn into Mary but I still miss you. Not the sex. It wasn't tragic, George. But I’ll live without it. I won’t make it if you can’t be my friend. If we can’t --
George: What you did today … you should be proud. I’ll get orderly to take you downstairs, but I have to go. Understand?
(George leaves and walks down the hallway, stops and goes back to be with Izzie)

Derek: You warned me she could become a problem.
Bailey: Who, Meredith?
Derek: You know when you love somebody, you think you can handle it all?
Bailey: You’ve done alright, both of you.
Derek: I came out here to be chief. And Meredith complicates that.
Bailey: Huh. Well if this turns into an “either or”, you pick the person you love, end of story. Look, all of this means nothing if you’re alone.

Meredith: (as she answers the door) Seriously.
Susan: Okay, that stops right now.
Meredith: It’s just, I’m waiting for Derek, and I’m very tired.
Susan: I don’t care. Let me in.
Meredith: Excuse me?!
Susan: It’s freezing out here and I’ve been working myself up to saying this, well for a while now. So I need you to let me in now, please. It’s my fault your father didn’t fight harder for you. I knew about you. I could have pushed him to be a part of your life. I should have pushed him. You were a child. We were the adults. But we were just married and it was new and that’s what I cared about. And I know the groceries and everything are a little much, but that’s just what I do. I mean, quit lookin’ at me like I’m crazy. ‘Cause that’s not fair. I’m just tryin’ to find a way to be there for you, the only way that I know how. And if you can’t accept that, then fine. Just stop being so rude. And I…okay, I’m overstepping again, aren’t I?
Meredith: As mothers go, I’ve only ever known overbearing, never overprotective. This is all new. It’s okay.
Susan: It is?
Meredith: Yes.

Meredith: So it’s weird, right? That Susan keeps stopping by like this? I mean, we just became friends or semi-related or whatever you call your estranged father’s wife.
Alex: You may be confused since you were basically raised by wolves, but this is what mothers do. They stop by, they stock your fridge. Dude, you think she might do our laundry?
Meredith: Hey, get your own fake mom.

Marlowe: Nothing like a quick ventricular reconstruction to jumpstart your morning, eh?
Cristina: Okay, you’ve officially become creepy. Creepy and stalking.

Mark: She pressed 5 and got off at 3. She’d rather walk up two flights of stairs than flirt with you. Hell, she’d rather climb up the outside of the building.
Webber: I wasn’t flirting.
Mark: You’re telling me!

Episode Title: Time After Time

"Time After Time" is the title of a song by Cyndi Lauper.

Episode Working Title: Ain't Nothing Like The Real Thing

"Ain't Nothing Like The Real Thing" is the title of a song by several artists including Marvin Gaye, Jackson 5, and Barry Manilow.