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Grey's Anatomy: The Heart of the Matter

Izzie reveals her true feelings for George to one of her and George's friends, and the reaction she receives is not what she expected. Meanwhile, Adele Webber rushes her niece to Seattle Grace; Derek gives Cristina pointers on how to be a better teaching resident; and Norman, the world's oldest intern, misdiagnoses Meredith's patient.

Episode Info

Episode number: 4x4
Production Number: 404
Airdate: Thursday October 18th, 2007

Director: Randall Zisk
Writer: Allan Heinberg

Alternate Airdates:

FI (Nelonen) Mar 19, 2008
NL (Net 5) Aug 18, 2008
UK (sky LIVING) Oct 02, 2008


Guest Stars
Edward HerrmannEdward Herrmann
As Intern Norman
Loretta DevineLoretta Devine
As Adele Webber (Wife of Dr. Richard Webber)
Camille WinbushCamille Winbush
As Camille Travis (Patient: Dr. Webber's Niece)
Maggie SiffMaggie Siff
As Ruthie Sales (Patient: Osteoporosis, Ankle Injury)
Matt LanterMatt Lanter
As Adam Singer (Patient: Spinal Injury From Football)
Michael McGradyMichael McGrady
As Stanley Singer (Father/Coach of Patient Adam Singer)
Miriam FlynnMiriam Flynn
As Ms. Bitzer (Patient: Crying Hospice Woman)
Ron MelendezRon Melendez
As Will Sales (Husband of Patient Ruthie Sales)

Co-Guest Stars
Gloria GarayuaGloria Garayua
As Intern Graciella
Jeremy RabbJeremy Rabb
As ER Doctor
Joy OsmanskiJoy Osmanski
As Intern Lucy
Maile FlanaganMaile Flanagan
As Lab Tech
Mark SaulMark Saul
As Intern Steve
Molly KidderMolly Kidder
As Intern Megan
Nicole CumminsNicole Cummins
As Paramedic
Richard KeithRichard Keith
As Intern Mitch
Tymberlee HillTymberlee Hill
As Intern Claire
Winston StoryWinston Story
As Intern Leo
Cassandra BradenCassandra Braden
As Housekeeping Staffer
Shelley RobertsonShelley Robertson
As Arlene Travis (Mother of Patient Camille Travis)
Main Cast
Ellen PompeoEllen Pompeo
As Dr. Meredith Grey
Justin ChambersJustin Chambers
As Dr. Alex Karev
Patrick DempseyPatrick Dempsey
As Dr. Derek Shepherd
Chandra WilsonChandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.James Pickens, Jr.
As Dr. Richard Webber
Sara RamirezSara Ramirez
As Dr. Calliope "Callie" Torres
Chyler LeighChyler Leigh
As Dr. Lexie Grey
Eric DaneEric Dane
As Dr. Mark Sloan
T.R. KnightT.R. Knight
As Dr. George O'Malley
Sandra OhSandra Oh
As Dr. Cristina Yang
Katherine HeiglKatherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 18.04 Million Viewers

Casting: In previous episodes that the character of Camille appeared, she was played by Tessa Thompson. In this episode Camille Winbush takes over the role.

ArtistSong TitlePlayed When
John LegendSun Comes UpDerek Tells Meredith How He Feels, Closing Scenes
Kim RicheyThe Absence Of Your CompanyWebber's Niece Talks About Her Cancer
MeikoHawaiiWebber's Niece Talks More About Her Cancer to Him
Northern StateBetter AlreadyOpening Scenes, Callie Gives a Surprising Response
Prince FattyMilk and Honey (featuring Hollie Cook)Izzie Walks Off, Lexie Talks to Derek and Cristina
Yeah Yeah YeahsRockers To SwallowCallie Meets Up with Izzie in the Cafeteria

Episode Quotes
Meredith: (opening voiceover) In life only one thing is certain, apart from death and taxes: No matter how hard you try, no matter how good your intentions, you are going to make mistake. You are going to hurt people. You are going to get hurt. And if you ever want to recover, there's really only one thing you can say.

George: Callie. you haven't said anything and...just say something. Please, anything.
Callie: I forgive you.
George: What?
Callie: You made a mistake, but we took vows, "'til death do we part," so...I forgive you.

Izzie: Callie! Hey. Hi.
Callie: We have to talk.
Izzie: Okay. Um, about?
Callie: George told me.
Izzie: He told you.
Callie: Everything. Cafeteria. Noon. You and me. Be there.

Izzie: No, she's saving all her rage and bloodshed for me. And she's gonna kill me in the cafeteria at lunch.
George: No, she wouldn't.
Izzie: She breaks bones for a living George! She's crazy!
George: No, she's not crazy.
Izzie: Well, she is if she thinks I'm not gonna put up a fight.

Bailey: People are stupid and just want to be loved. That's the only reason anyone does anything.

Cristina: You were very ghettofabulous.

Lexie: I just wanted to say thank you for saving my ass in surgery today.
Cristina: That's my job, 3.

Cristina: Oh, great. I'm stuck in the pit taking smack heads and gang bangers with my idiot interns and you're getting McDreamy'd in the elevator.
Meredith: Really, smack heads and gang bangers at Seattle Grace, huh?
Cristina: My point is, I hate interns.
Meredith: Well, Lexie's not that bad is she?
Cristina: Oh, are we not hating her any more?
Meredith: Oh no, we still hate the idea of her. We just realize we don't have reason to hate the actual person.
Cristina: She's an intern. That's reason enough.
Meredith: Oh, I think you may be the new Nazi.
Cristina: Damn right.

Meredith (closing voiceover): Forgive and forget. That's what they say. It's good advice, but it's not very practical. When someone hurts us, we want to hurt them back. When someone wrongs us, we want to be right. Without forgiveness, old scores are never settled. Old wounds never heal. And the most we can hope for, is that one day we'll be lucky enough to forget.

Cultural References
Episode Title: The Heart of the Matter

"The Heart of the Matter" is the title of a song by both Don Henley and India Arie.

Episode References
Season 4, Episode 3: George told Callie that he cheated on her with Izzie at the end of 4x03 "Let the Truth Sting".

Season 2, Episode 26: The Chief's niece, Camille Travis, was last in the hospital in 2x26 "Deterioration of the Fight or Flight Response" when her cancer returned.

Other Episode Crew

CreatorShonda Rhimes
Co-ProducerLisa Taylor (1)
Associate ProducerChris Van Dusen  |  Karin Gleason
CastingJohn Brace (1)  |  Linda Lowy
Unit Production ManagerJeff Rafner
First Assistant DirectorChris Hayden
Second Assistant DirectorShawn Hanley
MusicDanny Lux
Music EditorJennifer Barak
Music SupervisorAlexandra Patsavas
Costume DesignerMimi Melgaard
HairstylistSean Flanigan
Key GripMatt Mania
Set DecoratorKaren Bruck
Location ManagerGeorge Larson
Transportation CoordinatorTom Gilhooley
Property MasterAngela Whiting
Construction CoordinatorCurt Jones
Production Sound MixerBeau Baker
Script SupervisorNicole Cummins
Production CoordinatorWinter Zemans
Assistant EditorJoe Mitacek
Sound MixerDon Digirolamo  |  Todd Langer
Special EffectsJason Gustafson
Costume SupervisorTom Houchins
Special Makeup Effects ArtistBari Dreiband-Burman  |  Thomas R. Burman
Production AccountantGordon Loi
Chief Lighting TechnicianPeyton Skelton
Sound SupervisorTom Davis (1)
ResearcherElizabeth Klaviter
Department Head Make-upNorman Leavitt (1)
Production StaffMeg Marinis  |  Star Michael  |  Sonay Washington  |  Mark Saul
Theme Song Written And Performed ByPsapp
Medical ConsultantKaren Lisa Pike
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