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| Title: | Piece of My Heart |
| Episode Number: | 74 |
| Season: | 4 |
| Season Episode #.: | 13 |
| Production Number: | 413 |
| Original Airdate: | Thursday May 01st, 2008 |
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Addison makes her return to Seattle Grace in order to perform an operation. As she does so, she is preoccupied by all of the changes in her former co-workers' lives. Meanwhile, Meredith and Derek's clinical trial has its first patient, and Rebecca returns to deliver Alex some shocking news.
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This is the first appearance of Kate Walsh (Addison Montgomery) since "Didn't We Almost Have It All".
| Derek's middle name is Christopher.
| Ratings: 15.3 million viewers
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| Artist | Song Title | Played When | | •Greenskeepers | Money | | | •Jamie Lidell | Little Bit Of Feel Good | | | •Katalyst | See What You Feel | | | •Meaghan Smith | Five More Minutes | | | •Neverending White Lights | Distance | | | •Republic Tigers | Buildings and Mountains | |
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Callie: (to Addison) I like penis. I'm a huge huge fan of penis.
| (Derek is in the elevator with Meredith, Addison and Rose; Mark walks in)
Mark: Bet you're wishing you took the stairs right about now.
| Callie: Did anyone ever think you two were a couple?
Meredith: No because we screw boys like whores on tequila.
Cristina: And then we either try to marry them or drown ourselves.
| Meredith: Hey, you're leaving already?
Addison: I have a plane to catch. I walk on the beach now, I buy aromatherapy candles, I'm very zen, but I want to kick you ass so badly right now it is killing me.
Meredith: Excuse me?
Addison: I'm talking about Derek. Derek Christopher Shepherd. Are you letting him get away? Because I swear to God Meredith, if you let him ride off into the sunset with that doe-eyed little thing ... (she walks away).
| George: (to Izzie) You know, whenever anyone says something really funny and I laugh I always look around to see if you think it's funny too. Even when you are not there, I look around.
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Episode Title: Piece of My Heart
"Piece of My Heart" is the title of a song by several artists including Janis Joplin, Faith Hill and Lionel Richie.
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