Meredith: (opening voiceover) The problem with being a resident all the time is, you feeling crazy all the time. You haven't slept in years, you spend everyday around people with massive crisis, you lose your ability to judge what's normal in yourself or anyone else. And yet people are constantly asking you how you're doing? How the hell are you supposed to know? You don't even know how you're doing.
Dr. Wyatt: We had our first honest conversation about your feelings, and now you want to leave. That timing doesn’t strike you as strange?
Meredith: No, and I’m still firing you.
Dr. Wyatt: No, you’re quitting
Meredith: No, I’m not quitting. I don’t quit things
Dr. Wyatt: No, actually you do. Your mother quit your father. Your father quit you. You quit your boyfriend and if I read your hospital chart correctly you quit your life momentarily on a couple of occasions. You quit. It’s what you know how to do.
Meredith: Now you’re really fired.
Meredith: Cristina, are you in the dark place?
Meredith: Me too.
George: He punched someone named Harrison.
Bailey: You punched a child?
George: Apparently there was a graham cracker involved.
Bailey: Over a graham cracker?
George: They said they want you to talk to him.
Bailey: What, he's 14 months old? What do they think I'm going to do, give him a lecture on non-violent conflict resolution?
George: I really don't know.
Bailey: My son punches other children!
Lexie: I forgive you.
Lexie: No. I forgive you. I forgive you for treating me like crap, and I forgive you for letting your friend treat me like crap.
Lexie: I don't know how you get up in the morning, I honestly don't. Our dad abandoned you. And your mom by all accounts was the meanest person ever and you can't let Derek love you and it all really, really sucks. But ever since I knew you existed I had this fantasy about my big sister and you have failed, on every occasion to live up to that fantasy. But I still love you, whether you are capable of letting me or not. So, I forgive you.
Dr. Wyatt: Two o'clock work for you?
Meredith: Yeah, okay.
Chief: We need to write Adele again. She replied to my email but all she sent was a typo. She's no better at this than I am.
George: That's not a typo sir, that's a wink.
Chief: Well that's a semi-colon and a closed parenthesis.
George: Turn it sideways.
Chief: Well, what the hell does this mean?
George: She's flirting, sir.
Chief: Oh, oh, that's good!
Meredith: (closing voiceover) Don't wonder why people go crazy. Wonder why they don't. In face of what we can lose in a day, in an instant, wonder what the hell it is that make us hold it together.
Episode Title: Losing My Mind
"Losing My Mind" is the title of a song by Maroon 5.
Cinderella: Greta tells Derek a story about how she met her boyfriend. He found her shoe and brought it to her, and Derek says it sounds like the story of Cinderella.
Cinderella is a fairy tale and Disney film from 1950 where Prince Charming finds her glass slipper after a ball and returns it to her.
Season 3, Episodes 16 & 17:
Dr. Wyatt and Meredith talk about when she drowned in the water. Dr. Wyatt is referencing 3x16 "Drowning on Dry Land (2)
" and 3x17 "Some Kind of Miracle (3)
" in which during a ferry accident, Meredith falls into the water and nearly drowns. In the latter episode, Meredith has to be shocked several times in order to be brought back to life.
Season 2, Episode 16 & 17:
Dr. Wyatt and Meredith talk about the time she put her hand in a patient on an unexploded bomb. Dr. Wyatt is referencing 2x16 "It's the End of the World (1)
" and 2x17 "(As We Know It) (2)
" in which Meredith holds a grenade that was lodged inside of a patient in order to keep it from exploding.
Season 4, Episode 13:
Rebecca Pop/Ava came to the hospital in 4x13 "Piece of My Heart
" saying that she was pregnant, but Izzie ran tests and found out that she was not.
Season 4, Episode 13:
Derek and Meredith started working together on a clinical trial in 4x13 "Piece of My Heart
Season 2, Episode 17:
Bailey's baby, Tuck is 14 months old. This means 14 months of Grey's time has passed since Bailey gave birth to her son in 2x17 "As We Know It (2)