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Grey's Anatomy: The Self Destruct Button

Derek and Meredith try to spend a night together at Meredith's, but their appearance the next morning does more harm than they expected and leads Bailey to tell Meredith to end it. Alex treats a self-mutilation patient, while Izzie's patient literally won't let go of his girlfriend. Meanwhile, George is suspicious that an anesthesiologist is drinking on the job and Cristina fills ill with flu-like symptoms.

Episode Info
Episode number: 1x7
Production Number: 107
Airdate: Sunday May 08th, 2005

Director: Darnell Martin
Writer: Kip Koenig

Alternate Airdates:

AU (Seven) Sep 19, 2005
DE (Pro7) Apr 25, 2006
FR (TF1) Jul 17, 2006
FI (Nelonen) Oct 18, 2006

Guest Stars
Amanda MacDonaldAmanda MacDonald
As Claire Rice (Patient: Botched Gastric Bypass Surgery In Mexico)
Ever CarradineEver Carradine
As Athena (Girlfriend of Patient J.P.)
Kim Morgan GreeneKim Morgan Greene
As Mrs. Rice (Mother of Patient Claire Rice)
Russell HornsbyRussell Hornsby
As Digby Owens (Patient: Gun Shot Wound)

Co-Guest Stars
Sarah UtterbackSarah Utterback
As Nurse Olivia Harper
Shenita MooreShenita Moore
As Surgical Nurse
Bill BirchBill Birch
As J.P. (Patient: Swallowed His Girlfriend's Keys)
Doug SinclairDoug Sinclair
As Brett Hayes (Father of Patient Jamie Hayes)
Joseph KellJoseph Kell
As Mr. Rice (Father of Patient Claire Rice)
Larry CahnLarry Cahn
As Dr. Taylor (Attending Anesthesiologist, Drunk)
Rebecca  RogersRebecca Rogers
As Jamie Hayes (Patient: Brain Abnormality)
Regan FormanRegan Forman
As Gwen Hayes (Mother of Patient Jamie Hayes)
Steve MonroeSteve Monroe
As Orderly
Vanessa RogersVanessa Rogers
As Jamie Hayes (Patient: Brain Abnormality)
Main Cast
Ellen PompeoEllen Pompeo
As Dr. Meredith Grey
Justin ChambersJustin Chambers
As Dr. Alex Karev
Patrick DempseyPatrick Dempsey
As Dr. Derek Shepherd
Chandra WilsonChandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.James Pickens, Jr.
As Dr. Richard Webber
T.R. KnightT.R. Knight
As Dr. George O'Malley
Sandra OhSandra Oh
As Dr. Cristina Yang
Isaiah WashingtonIsaiah Washington
As Dr. Preston Burke
Katherine HeiglKatherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 18.86 Million Viewers

ArtistSong TitlePlayed When
Jem GriffithsWish IOpening Scenes, Meredith Wakes Derek
Joe PurdySuitcaseGeorge Watches Surgery, Burke Runs Down the Hall
Tegan & SaraDowntownIzzie Leaves After Confronting Meredith
WilcoHummingbirdIzzie and Meredith Talk in Kitchen, Closing Scenes

Episode Quotes
Meredith (opening voiceover): Okay. Anyone who says you can sleep when you die... Tell them to come talk to me after a few months as an intern. Of course it's not just the job that keeps us up all night. I mean if life's so hard already, why do we bring so much trouble on ourselves. What's up with the need to hit the self-destruct button?

Meeredith: Yikes, wouldn't want to meet you in a dark alley.
Cristina: Right back at 'ya. (Alex jogs up)
Izzie: A run? You run?
Alex: Every day, babe, every day.
Meredith: Not suffering enough?
Alex: What doesn't kill you, makes you stronger.
Cristina: Don't go acting all indefatigable. You're dragging like the rest of us.
Alex: Oh, what is that, professional weakness, Dr. Yang?
Cristina: It's called the flu.

Izzie: If you wait a few minutes you can have a piece of cake, baked chock full of love. Actually chock full of unrelenting, all-consuming rage and hostility, but still tasty.

Meredith: Why do I keep hitting myself with a hammer? Because it feels so good when I stop.

Meredith: I hate you! (takes a slice of cake from Izzie) And your cake!
Izzie: No, no, the cake is good.

Burke (taking the X-ray and showing it to Bailey walking by): You remember this guy?
Bailey: Hey, the tattooed masochist.
Burke: Had himself shot again.
Bailey: Glad to see he's still stupid.

Meredith: Thought you'd be asleep by now.
Izzie: Yeah, well ... I'm not. (pause) If you wait a few minutes, you can have a piece of cake. Baked it chock full of love. Actually, chock full of unrelenting, all-consuming rage and hostility, but -- still tasty.
Meredith: So you know?
Izzie: I know.
Meredith: Well, do you want the long, sordid version, or do you want the short version where I started sleeping with a guy who turned out to be my boss?
Izzie: Neither.
Meredith: Izzie, cut me some slack here.
Izzie: No! You went to Dartmouth. Your mother is Ellis Grey. You grew up -- look at this house! You know, you walk into the OR, and there isn't anyone who doubts that you should be there. I grew up in a trailer park. I went to state school. I put myself through med school by posing in my underwear. You know, I walk into the OR, and everyone hopes I'm the nurse. You-you have their respect without even trying, and you're throwing it away for ... what? A few good surgeries?
Meredith: No, it's not about the surgeries, it's not about getting ahead.
Izzie: Then what, a little hot sex? You're willing to ruin your credibility over that? I mean Meredith, what the hell are you doing? (Meredith rolls her eyes) Oh my god... you're falling for him.
Meredith: I am not.
Izzie: Oh you so are.
Meredith: No, I'm not.
Izzie: So are... Dammit. You poor girl.

George: I'm sorry, but did you just.....have you been drinking?
Dr. Taylor: I beg your pardon?
Derek: What?
George: Do you smell.....? I smell alcohol.
Dr. Taylor: Where the hell do you get off accusing me of something like that?
Derek: George, you're out of line.
George: There are rules. You know, there are rules for a reason. There is a 2-year-old girl on this table! You shouldn't take advantage of someone else's vulnerability.
Dr. Taylor: I don't need some punk intern telling me what's at stake here. (to Derek) Get him out of here, Shep. Shep?
Derek: You're out, George.

Meredith (closing voiceover): Maybe we like the pain. Maybe we're wired that way. Because without it, I don't know, maybe we just wouldn't feel real. What's that saying? Why do I keep hitting myself with a hammer? Because it feels so good when I stop.

Episode Goofs

When Izzie leaves the house, she has a purple travel coffee mug. When she gets out of the car, it is a disposable mug, but when she leaves the locker room, she is holding the purple mug again.


When Jamie is being examined by George you can tell that the shot of her legs twitching are not the same legs as the original little girl. In the shot of her leg twitching he has no shirt on. In the next, she is wearing a shirt.


Izzie is surprised to discover that Derek and Meredith are sleeping together. She should already know about their relationship because she was there when Cristina yelled at Meredith about it in the pilot episode.


Claire's parents should know about the scars on her abdomen because they told Meredith that she had collapsed in the shower. Unless she showers fully clothes, they should have seen the scars.

Cultural References
Episode Title: The Self Destruct Button

The Self Destruct button is the title of a song by AC/DC and Dana Monteith.

Episode References
Season 1, Episode 6: Derek spent the night at Meredith's house after they went home together in 1x06 "If Tomorrow Never Comes."

Other Episode Crew

CreatorShonda Rhimes
Co-ProducerAnn Kindberg  |  Tammy Ann Casper
Production DesignerLaurence Bennett
EditorEdward Ornelas  |  Victor Du Bois  |  Briana London
CastingJohn Brace (1)  |  Linda Lowy
Unit Production ManagerAnn Kindberg
First Assistant DirectorChris Hayden
Second Assistant DirectorJim Goldthwait
MusicDanny Lux
Costume DesignerLinda Bass
HairstylistSean Flanigan
Property MasterRyan Blank
Script SupervisorNicole Cummins
Production CoordinatorSue Jennings
Director of PhotographyTim Suhrstedt
Story EditorZoanne Clack
Costume SupervisorGail Just
Department Head Make-upNorman Leavitt (1)
Theme Song Written And Performed ByPsapp
Missing Information
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