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Grey's Anatomy: Brave New World

Meredith is sent into a state of panic when Derek finds her mother's diary in the house. Meanwhile, Callie stresses while preparing for her first date with Erica. Later, Cristina stumbles across a part of the hospital no one has ever seen before.

Episode Info

Episode number: 5x4
Production Number: 504
Airdate: Thursday October 16th, 2008

Director: Eric Stoltz
Writer: Debora Cahn

Alternate Airdates:

NL (Net 5) Dec 15, 2008
FI (Nelonen) Jan 21, 2009
UK (sky LIVING) Feb 12, 2009
AR (Canal 9) Feb 23, 2009

  • Currently 7.5/10
7.5/10 (30 Votes cast)


Guest Stars
Kathleen Early
As Dr. Daisy Pepman (First Year Dermatology Resident)
Steven W. Bailey
As Joe (The Bartender at Emerald City Bar)
Amy Aquino
As Marianne Grandy (Wife to Arnie Grandy)
Bre Blair
As Lauren Pailey (Mother of Ducan Pailey)
John Sloan
As David Pailey (Father of Duncan Pailey)
Larry Brandenburg
As Arnie Grandy (Patient: Brain Tumor, Husband to Marianne Grandy)
Max Burkholder
As Duncan Pailey (Patient: Young Boy Scheduled for Heart Surgery)

Co-Guest Stars
Amrapali Ambegaokar
As Intern Dani
Candice Afia
As Intern Laura
Gloria Garayua
As Intern Graciella
Joseph Williamson
As Intern Pierce
Mark Saul
As Intern Steve
Molly Kidder
As Intern Megan
Tymberlee Hill
As Intern Claire
Winston Story
As Intern Leo
Carol Ann Susi
As Mrs. Dorsokowski (Patient: In Clinic, Has a Rash)
Main Cast
Ellen Pompeo
As Dr. Meredith Grey
Justin Chambers
As Dr. Alex Karev
Patrick Dempsey
As Dr. Derek Shepherd
Chandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.
As Dr. Richard Webber
Sara Ramirez
As Dr. Calliope "Callie" Torres
Brooke Smith
As Dr. Erica Hahn
Chyler Leigh
As Dr. Lexie Grey
Eric Dane
As Dr. Mark Sloan
T.R. Knight
As Dr. George O'Malley
Sandra Oh
As Dr. Cristina Yang
Katherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 14.57 Million Viewers

Trivia: Max Burkholder ('Duncan Pailey') is now a star of the NBC drama 'Parenthood'. He plays the character of Max Braverman, a young boy with autism.

ArtistSong TitlePlayed When
Bernadette MoleyLove to MeBar Scene, Celebrating, Lexie Orders a Drink
The Bird and the BeeMy LoveGeorge Teases Meredith, Hahn Watches Callie
Brett DennenAin't Gonna Lose YouIzzie Comforts Patient's Wife, Goes to Dermatology
Emiliana TorriniBig JumpsBailey Helps Callie, Dermatology Department Scene
Joshua RadinOne of Those DaysGeorge Prepares a Young Patient to See the O.R.
Patrick & EugeneAltogether NowOpening Scenes, Seattle, Izzie Fidgets By Door
The RescuesMy Heart with YouCallie and Hahn at Dinner, Closing Scenes
The Whitest Boy AliveDone with YouCristina Tends to a Patient, Alex Angry with Izzie

Episode Quotes
Meredith: (opening voiceover) In 6500 BC, some guy looked at his friend and said, let's drill a hole in your head... that will make you feel better. And thus surgery was born. It takes a certain brand of crazy to think of drilling into someone's skull, but surgeons have always been a confident bunch. We don't always know what we're doing, but we act like we do. We walk into a country, plant a flag and start ordering people around. It's invigorating and terrifying.

Izzie: Give me back my surgery or I'll shoot your ass off!

Izzie: People are terrible to the people they love sometimes. They're mean. You were both having a hard time and you took it out on each other. It doesn't make you the worst wife in the world. It just makes you a person who made a mistake.

Cristina: We are not happy, glowy people.
Izzie and Meredith: Yeah.
Cristina: We need to get out of here.
Izzie and Meredith: Yeah.

Erica: Lie to me again and the only heart you'll ever see is yours as I'm cutting it out of your chest with a steak knife.

Meredith: (closing voiceover) We like to think we're fearless, eager to explore unknown lands and soak up new experiences, but the fact is, we're always terrified. Maybe the terror is part of the attraction. Some people go to horror movies. We cut things open. Dive into dark water. And at the end of the day, isn't that what you'd rather to hear about? If you've got one drink and one friend and 45 minutes. Slow rides make for boring stories. A little calamity. Now that's worth talking about.

Cultural References
Episode Title: Brave New World

"Brave New World" is the title of a song recorded by several artists including Iron Maiden, Styx, Motorhead, and Steve Miller Band.

Other Episode Crew

CreatorShonda Rhimes
Executive ProducerBetsy Beers  |  Mark Gordon (4)  |  Allan Heinberg  |  Mark Wilding  |  Rob Corn  |  Shonda Rhimes  |  Krista Vernoff
ProducerTammy Ann Casper  |  Linda Klein
Series DirectorKevin McKidd
WriterShonda Rhimes
Warning: Grey's Anatomy season 5 episode 4 guide may contain spoilers
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