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Grey's Anatomy: These Ties That Bind

Sadie, one of Meredith's oldest friends, is brought on as an intern at Seattle Grace; however, Meredith's friends are less than welcoming to her. Meanwhile, Lexie leads the interns on a unique training session; and Virginia, a new surgeon, brings new rules to the O.R.

Episode Info

Episode number: 5x8
Production Number: 508
Airdate: Thursday November 13th, 2008

Director: Eric Stoltz
Writer: Stacy McKee

Alternate Airdates:

FI (Nelonen) Feb 18, 2009
UK (sky LIVING) Mar 12, 2009
NL (Net 5) Mar 23, 2009

  • Currently 8.7/10
8.7/10 (32 Votes cast)


Special Guest Stars
Jeffrey Dean Morgan
As Denny Duquette

Guest Stars
Kevin McKidd
As Dr. Owen Hunt (New Trauma Surgeon)
Mary McDonnell
As Dr. Virginia Dixon (Cardiac Surgeon With Asperger's Syndrome)
Melissa George
As Sadie Harris (New Intern, Old Friend of Meredith's)
August Schellenberg
As Clay Bedonie (Patient: Navajo Indian, Heart Transplant)
Ed Lauter
As Timothy Miller (Patient: Homeless Man, Impaled in Garbage Truck)

Co-Guest Stars
Gloria Garayua
As Intern Graciella
Joseph Williamson
As Intern Pierce
Mark Saul
As Intern Steve
Molly Kidder
As Intern Megan
Nicole Cummins
As Paramedic Jill
Winston Story
As Intern Leo
Main Cast
Ellen Pompeo
As Dr. Meredith Grey
Justin Chambers
As Dr. Alex Karev
Patrick Dempsey
As Dr. Derek Shepherd
Chandra Wilson
As Dr. Miranda Bailey
James Pickens, Jr.
As Dr. Richard Webber
Sara Ramirez
As Dr. Calliope "Callie" Torres
Chyler Leigh
As Dr. Lexie Grey
Eric Dane
As Dr. Mark Sloan
T.R. Knight
As Dr. George O'Malley
Sandra Oh
As Dr. Cristina Yang
Katherine Heigl
As Dr. Isobel "Izzie" Stevens
Episode Notes
Ratings: 15.59 Million Viewers

Casting: Brooke Smith (Erica Hahn) has been removed from the opening credits.

ArtistSong TitlePlayed When
Lenka KripacTrouble is a FriendLexie Sighs, Alex Finds Izzie, Plays Almost to End
SeabirdFalling for YouWebber Praises Cristina, Patient Begins Crashing
Walking SleepThe Uniform (as The Flying Tourbillon Orchestra)Opening Scenes, Izzie Gets Up and Sniffs a Sweater

Episode Quotes
Meredith: (opening voiceover) It's intense, what happens in the O.R. when lives are on the line. And you're poking at brains like they're silly putty. You form a bond with the surgeons right next to you. An unbreakable, indescribable bond. It's intimate, being tied together like that. Whether you like it or not, whether you like them or not, you become family. The ties that binds us are sometimes impossible to explain. They connect us even after it seems like the ties should be broken. Some bonds defy distance and time and logic; Because some ties are simply... meant to be.

Meredith: (to Derek) I need you to tell Mark to keep his little Sloan out of little Grey.

Izzie: I said goodbye. I burned the sweater!
Denny: Yeah, thanks for that, by the way. I loved that sweater. You made me that sweater. Izzie, stop freaking out.
Izzie: You're not real. You're not real.
Denny: Hey, I told you.
Izzie: You're not real! You're not real! You're not real!
Denny: Look at me. Touch me. (Izzie touches Denny) See? Told you I was real.

Cristina: I'm sorry. We lost him. The patient. I'm sorry.
Owen: I don't need you to be sorry. I don't need you to be sorry. I don't need you ...
Cristina: Alright, alright. (they kiss)

Meredith: (closing voiceover) The ties that binds us are sometimes impossible to explain. They connect us even after it seems like the ties should be broken. Some bonds defy distance and time and logic because some ties are simply meant to be.

Episode Goofs
Factual Error:

Dr. Virginia Dixon tells Bailey that the first successful heart transplant was performed in 1896 by Dr. Ludwig Rehn, which is actually wrong. The first successful heart surgery, not heart transplant, was performed by Dr. Ludwig Rehn in 1896. The first cardiac transplantation was not performed until 1967 by Dr. Christiaan Barnard in South Africa.

Cultural References
Episode Title: These Ties That Bind

"These Ties That Bind" is a take on the Bruce Springsteen song, "The Ties That Bind."

Popular Culture:

The Wizard of Oz: Christina says to Derek "Still no word on what made H hitch a ride with the flying monkeys," in reference to Hahn leaving the hospital.

Episode References
Season 2, Episode 27: Denny Duquette was Izzie's fiance from season two of Grey's Anatomy. She repeatedly seems his walking throughout the hospital and has conversations with him, even though he passed away in 2x27 "Losing My Religion".

Other Episode Crew

CreatorShonda Rhimes
Executive ProducerBetsy Beers  |  Mark Gordon (4)  |  Allan Heinberg  |  Mark Wilding  |  Rob Corn  |  Shonda Rhimes  |  Krista Vernoff
ProducerTammy Ann Casper  |  Jeff Rafner  |  Linda Klein  |  Zoanne Clack  |  Stacy McKee
Series DirectorKevin McKidd
WriterStacy McKee
Missing Information
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Warning: Grey's Anatomy season 5 episode 8 guide may contain spoilers
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