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Sadie, one of Meredith's oldest friends, is brought on as an intern at Seattle Grace; however, Meredith's friends are less than welcoming to her. Meanwhile, Lexie leads the interns on a unique training session; and Virginia, a new surgeon, brings new rules to the O.R.
Ratings: 15.59 Million Viewers
Casting: Brooke Smith (Erica Hahn) has been removed from the opening credits.
Meredith: (opening voiceover) It's intense, what happens in the O.R. when lives are on the line. And you're poking at brains like they're silly putty. You form a bond with the surgeons right next to you. An unbreakable, indescribable bond. It's intimate, being tied together like that. Whether you like it or not, whether you like them or not, you become family. The ties that binds us are sometimes impossible to explain. They connect us even after it seems like the ties should be broken. Some bonds defy distance and time and logic; Because some ties are simply... meant to be.
Meredith: (to Derek) I need you to tell Mark to keep his little Sloan out of little Grey.
Izzie: I said goodbye. I burned the sweater!
Denny: Yeah, thanks for that, by the way. I loved that sweater. You made me that sweater. Izzie, stop freaking out.
Izzie: You're not real. You're not real.
Denny: Hey, I told you.
Izzie: You're not real! You're not real! You're not real!
Denny: Look at me. Touch me. (Izzie touches Denny) See? Told you I was real.
Cristina: I'm sorry. We lost him. The patient. I'm sorry.
Owen: I don't need you to be sorry. I don't need you to be sorry. I don't need you ...
Cristina: Alright, alright. (they kiss)
Meredith: (closing voiceover) The ties that binds us are sometimes impossible to explain. They connect us even after it seems like the ties should be broken. Some bonds defy distance and time and logic because some ties are simply meant to be.
Dr. Virginia Dixon tells Bailey that the first successful heart transplant was performed in 1896 by Dr. Ludwig Rehn, which is actually wrong. The first successful heart surgery, not heart transplant, was performed by Dr. Ludwig Rehn in 1896. The first cardiac transplantation was not performed until 1967 by Dr. Christiaan Barnard in South Africa.
Episode Title: These Ties That Bind
"These Ties That Bind" is a take on the Bruce Springsteen song, "The Ties That Bind."
The Wizard of Oz: Christina says to Derek "Still no word on what made H hitch a ride with the flying monkeys," in reference to Hahn leaving the hospital.