Ratings: 13.71 Million Viewers
Casting: The first appearance of Jessica Capshaw as pediatric surgeon Arizona Robbins.
Trivia: It was Izzie's birthday in this episode, which suggests that her birthday is on January 8th.
Meredith: (opening voiceover) We all get at least one good wish a year over the candles on our birthday. Some of us throw in more. On eyelashes, fountains, lucky stars, and every now and then, one of those wishes comes true. So what then? Is it is as good as we'd hoped? Do we bask in the warm glow of our happiness? Or, do we just notice we've got a long list of other wishes waiting to be wished?
Owen: You okay? Want to get a drink or something?
Cristina: Oh. Oh now we're on again because the mood suits you? Because I'm the sad little girl with no friends and I tripped your savior complex into action? Usually I can deal with the hot and cold thing, but not today. Just leave me the hell alone.
Lexie: From the lab, Dr. Sloan. (pauses) Did you need something else?
Mark: (to Callie) This is toture.
Mark: I'm telling you, these interns are out of control.
Mark: Sexed-up stalkers.
Mark: We did good work today.
Callie: If we stay strong --
Mark: Don't get drunk --
Callie: Keep staring at Joe; we'll be fine.
Callie: (about Lexie) You slept with her?
Mark: Absolutely not. Only once. She came to my hotel room, took off all her clothes and said "teach me." It was like I had no control. She violated me with her nakedness. Derek's gonna kill me.
Callie: Well, you shouldn't have been alone with her.
Mark: Never gonna happen again, mind-blowingly fantastic as it was.
Callie: Hey, you are a professional, all right? (Sadie walks over them)
Sadie: Hey. Oh. Hold on. Hold tight. Just a bit of lint. Um, ultrasound's backed up, but they said they'll have results in half an hour.
Callie: All right. Uh .. well ... tell, uh, tell Grey. Uh, and ... uh ... let ... uh, let, uh George -- Dr. George -- Dr. O'Malley -- know when, uh, let him know... let him know when you know, okay?
Mark: You were saying something about professionalism?
Chief: (to Derek) I'm worried about my hospital dying. I made some calls to replace Kinley. No one wants to come here. I can't keep a cardiac surgeon on staff. Burke quit. Hahn quit. Dixon's autistic. My OR roof collapsed, the whole place flooded. The interns are literally chopping each other into little pieces. No wonder we're number twelve. Twelve!
Meredith: All crimes are crimes of passion. There's always a reason. People don't do stuff like that because they forget it's illegal.
Meredith: (closing voiceover) We don't wish for the easy stuff. We wish for big things. Things that are ambitious, out of reach. We wish because we need help and we're scared and we know we may be asking too much. We still wish, though, because sometimes they come true.
The interns would not have asked what "PDR" (used in this episode to stand for "Prisoner, Death Row") meant. Instead, they would have been confused by that acronym, since to them, "PDR" would surely stand for "Physician's Desk Reference", one of the most common reference books for physicians.
The state of Washington does not have the death penalty and, therefore, has no death row prisoners.