Ratings: 12.95 Million Viewers
Trivia: In this episode it's revealed that Lexie is 24 years old.
Guest-star Tyne Daly's step-brother Tim Daly is cast-member of the Grey's Anatomy spin-off Private Practice.
'Sympathy for the Devil' shares its name with an episode of the CW show 'Supernatural'. Jeffrey Dean Morgan, who appears as Denny Duquette in this episode, plays a leading role in "Supernatural".
Meredith: (opening voiceover) My mother used to say this about residency: "It takes a year to learn to cut. It takes a lifetime to learn not to." Of all of the tools on the surgical tray, sound judgement is the trickiest one to master. And without it, we are all just toddlers running around with ten-blades.
Arizona: (to Alex) You don't think that I know that they just pulled the plug on the kid? You don't think that I get that? You don't think I know about the tiny, tiny coffin that they're going to stick him in? I know about the tiny coffins. I see them all the time. In my sleep. So if you don't mind, I'm going to keep talking relationships and rainbows and crap. And I'm going to make plans for tomorrow. Because that's what you do, Karev, you make plans. You have to. You turn your back on the tiny coffins and you face forward until the next kid.
Mark: Why do you have to live in Meredith's attic? How am I supposed to sneak out of here with a frat party going on downstairs? Don't you kids ever sleep?
Lexie: They're cleaning the house for Dr. Shepherd's mom.
Mark: Mrs. Shepherd's coming to Seattle?
Mark: So that woman practically raised me, taught me right from wrong. If she found that I was with you ... that we were ... you're Meredith Grey's little sister. You are forbidden fruit. You are twenty-five. You're a fetus.
Lexie: Twenty-four. I skipped third grade.
Mark: I feel dirty.
Derek: You are wearing an alarmingly high ponytail.
Meredith: Your mother is coming!
Izzie: (to Cristina) I think it's nice. Your date. I think you and the pig-murderer make a really good couple.
Mark: Pain and agony for a little bit of pleasure? I get it.
Callie: If it's that bad, why don't you stop sl -- ... doing what you're doing.
Mark: Because it doesn't feel bad when I'm ... doing it. It's good. It's great. And maybe if you weren't so scared of getting burned, you'd feel the same.
Carolyn: You've been avoidng me.
Mark: What? No.
Carolyn: You've got that same look on your face as you did when you were ten years old. You put Derek's favorite frog into the microwave.
Carolyn: How many sexual partners have you had? I won't judge.
Lexie: Six. No, seven. Kind of six. Kind of seven.
Carolyn: Criminal record?
Lexie: Speeding ticket.
Carolyn: How fast?
Lexie: Twelve miles over.
Carolyn: That's fast.
Lexie: It wasn't too ... it was way too fast, but I was downhill. I was coasting, ma'am.
Carolyn: Now I don't suppose you can tell me ... where the gift shop is?
Meredith: (closing voiceover) We're human. We make mistakes. We mis-estimate. We call it wrong. But when a surgeon makes a bad judgement call, it's not as simple. People get hurt. They bleed. So we struggle, over every stich. We agonize over every suture. Because the snap-judgements, the ones that come to us quickly and easily, without hesitation, they're the ones that haunt us forever.