This episode is a cross-over episode with Private Practice and a continuation of the Private Practice episode "Ex-Life."

This episode featured no closing voiceover.

Addison: (to Derek) You were ... you were a God today. You were a God today in that O.R. You slew dragons, you walked on water, you, you were a God, but now, now you need to get very tiny again and go back in the box.

Mark: I'm an ass.
Addison: You're such an ass.
Mark: I shouldn't have blurted.
Addison: Uh, a little warning would've been nice.
Mark: But you're okay?
Addison: Yeah, you know, it strange. I expected this horrible feeling, this wave of sadness or something to just take over, but people get divorced, they meet new people, they remarry. I don't kow, you know, things just ... Maybe seeing Archer in that O.R., it just changed my perspective or something.
Mark: But you sort of wished it had been you first.
Addison: Oh, shut it. So, what are you gonna tell Derek about the -- okay, wait, wait. If we call Meredith the 12 year old, what do we call Lexie? A preschooler?
Mark: She's a woman.
Addison: Oh, okay.
Mark: I'm gonna tell him. I'm working on it.

(Addison is watching the surgery in the gallery)
Addison: Say it, Derek. Say it, say it, say it.
Derek: (looking up at Addison) Okay, people it's a beautiful day to save lives.

Chief: I just got out of surgery. What's goin' on?
Alex: She needs a prize.
Izzie: A big prize, but not too big, because they did take out their own appendixes. I understand that they're still being punished for that, and that you think that they're not even authorized to hold a clamp. So, do you have any prizes like that?
George: Alright, they just diagnosed the syptoms for their final patients, so get out the finish line. It's gonna be close.

Episode Title: Before and After

"Before and After" is the title of a song by Rush.