Meredith: (opening voiceover) Every surgeon I know, has a shadow. A dark cloud of fear and doubt, that follows even the best of us into the O.R. We pretend the shadow isn't there. Hoping that if we save more lives, master harder techniques, run faster and farther, it'll get tired and give up the chase. But, like they say, you can't outrun your shadow.

Lexie: Yes, the odds are against us. I'm a one woman wrecking ball, all I do is break you. Your hand, your penis, your relationships, your life. I'd say our survival rate is about 3 percent. And that's -- that's, that's bad. But, it's not nothing. And I don't think we should give up on this. At least not yet because (Mark puts his finger on her lips) Okay.
Mark: You think you broke me Little Grey? You're the one that put me back together.

Beth: I seized during the performance? But I took my meds.
Alex: Relax. It's not like you crapped your pants or anything.
Beth: But it is like I crapped my pants. I had a seizure in front of the entire marching band. It is exactly like I crapped my pants. They're going to kill me.
Alex: Who?
Beth: Seizure patrol.

Alex: You want me to sit here and babysit the band nerd? That's an intern job.
Owen: I don't see any interns around.

Mark: (to the Chief) Well, it wasn't easy. Not only did I push through my harelip reconstruction and a tympioplasty but I pulled out a burn graft so beautiful it could bring a grown man to tears.

Chief: I know I have no business asking you for anything, but I need your help. I need you to bring Derek back. And he's not fine.
Meredith: Sometimes people just wanna be left alone.
Chief: He's planning to propose. He's been carrying around a big ring for weeks. That's not a man who wants to be left alone. I just thought you should know.

Meredith: You cleaned all of your clothes out of the closet at the house.
Derek: Go home, Mer. Just go home.
Meredith: Well, how long are you planning on hiding out here? Because that's what you're doing. You're hiding. You made a mistake. She's dead and you can't hide from that.
Derek: I'm not hiding. I'm done. I'm done operating.
Meredith: Oh, okay. So you're just quitting?
Derek: You should understand better than anybody else. You wrote the book on quitting. Running, hiding, you've written a lot of books Meredith.
Meredith: That may be true. But I'm here now.
Derek: Oh, ah, you're here now? You've wanted me out since the day I moved in.
Meredith: That is not true.
Derek: Because you're incapable of anything that resembles commitment. You lied to me, you said you were healthy. That you were healed. There's no fixing you. You're a lemon.
Meredith: Derek Shepherd you are drunk! And you're angry, and I've been there so I get it. But that does not give you the right --
Derek: Just go home Meredith.
Meredith: You don't get to just stand here and tell me to leave.
Derek: This is what you want, I'm giving you an out. Go.
Meredith: I'm not going anywhere.
Derek: I said leave! Meredith, leave!
Meredith: I know there's a ring.
Derek: What?
Meredith: The Chief told me. I know there's a ring.
Derek: You want the ring? Here's your ring. (Derek hits it into the field with a baseball bat)
Meredith: Is that the best you've got? 'Cause I'm not bailing. we're in this together!
Derek: Go home, Meredith!

Meredith: (closing voiceover) Every surgeon has a shadow. And the only way to get rid of a shadow,is to turn off the lights. To stop running from the darkness, and face what you fear, head on.

During the operation on the first sibling, the Chief's position changes between shots.

The surgeons would not have implanted a pacemaker into the band member and THEN made arrangements for her to visit a cardiologist--the cardiologist would have been involved in the selection of the type of pacemaker.

Episode Title: I Will Follow You Into the Dark

"I Will Follow You Into the Dark" is the title of a song by Death Cab for Cutie.

Derek: There's just so many people. More than Dahmer, Manson, and Bundy combined.

Jeffery Dahmer, Charles Manson, and Ted Bundy are all infamous serial killers.