| •Murray Bartlett | played | Cyrus Foley (2007-present) |
| •Rob Bogue | played | A.C. Mallet #2 (2005-present) |
| •Mandy Bruno | played | Marina Cooper #6 (2004-present) |
| •Crystal Chappell | played | Olivia Spencer Lewis (1999-present) |
| •Jordan Clarke | played | Tim Ryan/Harlan Billy Lewis II #1 (1974-77 (as Tim)/83-87, 89-93, 96, 98, 99-present) |
| •Bradley Cole | played | Richard Winslow/Jeffrey O'Neill (1999-02(as Richard)2003-present(as Jeffrey) |
| •Justin Deas | played | Frank 'Buzz' Cooper, Sr. (1993-present) |
| •Bonnie Dennison | played | Susan "Daisy" Lemay #2 (2006-present) |
| •Frank Dicopoulos | played | Frank Cooper (1987-present) |
| •John Driscoll | played | Henry Cooper Bradshaw #2 (2004-present) |
| •Beth Ehlers | played | Harley Davidson Cooper Spaulding Mallet Spaulding Aitoro (1987-1993, 97, 1997-present) |
| •Nicole Forester | played | Cassandra Elizabeth Rae Layne Winslow Winslow #2 (2005-present) |
| •Ricky Paull Goldin | played | Gus Aitoro (aka Nick Augustino) (2001-present) |
| •Michael O'Leary | played | Rick Bauer #5 (1982-1991, 1995-present) |
| •Robert Newman (2) | played | Josh Lewis (1981-1984, 1986-1991, 1993-present) |
| •Tom Pelphrey | played | Jonathan Randall #2 (2004-present) |
| •Ron Raines | played | Alan Spaulding #3 (1994-present) |
| •Marcy Rylan | played | Elizabeth Lillian Spaulding #5 (2006-present) |
| •Michelle Ray Smith (3) | played | Ava Peralta (2005-Present) |
| •Gina Tognoni | played | Dinah Marler Thorpe Jessup Mallet #4 (2004-present) |
| •Kim Zimmer | played | Reva Shayne Lewis (1983-1990, 1995-present) |
| •Elizabeth Keifer | played | Christina Blake Thorpe Spaulding Spaulding Marler Marler #5 (1992-present (currently recurring)) |
| •Yvonna Wright | played | Melissande 'Mel' Boudreau Bauer (2001-present (currently recurring)) |
| •Beth Chamberlin | played | Beth Raines Spalding Winslow (1989-1991, 1997-present (currently recurring)) |
| •Kim Brockington | played | Felicia Boudreau #2 (2002-present (currently recurring)) |
| •Tina Sloan | played | Lillian Raines (1983- Present (currently recurring)) |
| •Marj Dusay | played | Alexandra Spaulding #2 (1993 -1997,1998-1999; 2002- (currently recurring)) |
| •Morgan Englund | played | Dylan Shayne Lewis (1989-1995, 2007-present) |
| •Nicholas Art | played | Alan 'Zach' Spaulding #2 (2002-present (under five uncredited)) |
| •Gavin Houston | played | Remy Boudreau #2 (2002-present) |
| •Maureen Garrett | played | Holly Norris Bauer Thorpe Lindsey Reade #2 (1976-80, 88-03, 04-present (currently recurring)) |
| •Stephanie Gatschet | played | Tammy Layne-Winslow #2 (2002-2007) |
| •Michael Dempsey (1) | played | Alan-Michael Spaulding #5 (2005-2007) |
| •Paul Fitzgerald (1) | played | Colin McCabe (2006) |
| •Justin Klosky | played | Joey Lupo (2003-2005, 06) |
| •Crystal Hunt | played | Lizzie Spaulding #5 (2003-2006) |
| •Scott Bailey | played | Sandy Foster (2003-2006) |
| •David Andrew MacDonald (2) | played | Edmund Winslow (1999-2006) |
| •Maeve Kinkead | played | Vanessa Chamberlain Lewis Reardon (1980 - 1987; 1989 - 1996; 1997 - 2000; 02; 05, 06) |
| •Kurt McKinney | played | Matt Reardon (1994-2000, 2005) |
| •Paul Anthony Stewart | played | Danny Santos (1998-2005) |
| •Nancy St. Alban | played | Michelle Bauer Santos #5 (2000-2005) |
| •Doug Hutchison (1) | played | Sebastian Hulce (2004-2005) |
| •Jerry ver Dorn | played | Ross Marler (1979-2005) |
| •George Alvarez | played | Ray Santos (#2) (1999-05) |
| •Grant Aleksander | played | Phillip Granville Spaulding #2 (1982-1984; 1987-1991; 1996-2005) |
| •Daniel Cosgrove | played | Harlan 'Bill' Lewis III (#3) (2002-05) |
| •Carrie Nye | played | Carolyn "Carrie" Carruthers (2003-2004) |
| •Russ Anderson | played | Christopher Langham (2003-2004) |
| •Marty West | played | Shayne Lewis #7 (2003-2004) |
| •Tonja Walker | played | Marie Green (2003-2004) |
| •Deborah Zoe | played | Eden August #2 (2003-2004) |
| •Orlagh Cassidy | played | D.A. Doris Wolfe (1997 - 2003; 2004) |
| •Mark Pinter | played | Mark Evans/ Brad Green (1981-83 (as Mark)/2003-04 (as Brad)) |
| •Gil Rogers | played | Hawk Shayne (1985 - 1990; 1995-1997; 2002; 2004) |
| •MacKenzie Mauzy | played | Elizabeth "Lizzie" Spaulding #3 (2000-2003) |
| •Matthew Bomer | played | Ben Reade #3 (2001-2003) |
| •Troy Kurtis | played | Nico Castaño (2002-2003) |
| •Billy Kay (2) | played | Shayne Lewis #6 (1999-2003) |
| •Michael Swan | played | Brad Green (2003) |
| •Thom Christopher (1) | played | Colonel Dax (Jul 1999 - Feb 19, 2002; 2003) |
| •Linda Cook | played | Brenda Jensen (2003) |
| •Richard Biggs | played | Clayton Boudreau (#1) (2001-2003) |
| •Colleen Dion | played | Ramona Hendon (2003) |
| •Allison Hirschlag | played | Elizabeth 'Lizzie' Spaulding (#4) (2002-2003) |
| •Miriam Colon | played | Maria Santos #2 (1999-2002) |
| •Joan Collins | played | Alexandra Spaulding von Halkein Thorpe #3 (2002) |
| •Jennifer Rozzell | played | Eleni Andros Cooper #3 (1995-2000, 2001-2002) |
| •Wesley A. Ramsey | played | Sam Spencer (2000-2002) |
| •Paul Michael Valley | played | Joel Silver (2002) |
| •Shari Headley | played | Felicia Boudreau (#1) (2001-2002) |
| •Stephen Schnetzer | played | Cass Winthrop (2002) |
| •Rebecca Hollen | played | Trish Lewis Norris (1980 - 1985; 1997; 2002) |
| •Mary Kay Adams (1) | played | India von Halkein Spaulding (1984 - 1987; 1990 - 1991; 1998 - 1999; 2002) |
| •Susan Pratt | played | Claire Ramsey (1983 - 1986; 2000-2002) |
| •Michael Philip | played | Dr. Ethan Pierce (2002) |
| •Laura Bell Bundy (1) | played | Marah Shayne Lewis #6 (1999-2001) |
| •Teresa Hill (1) | played | Eden August #1 (2002-2003) |
| •Magaly Colimon | played | Ruth Lockhart (1999-2001) |
| •Brittany Snow | played | Susan Lemay (aka Daisy Cooper) (1998 - 2001) |
| •Elizabeth Hobgood | played | May Merisi (2000-2001) |
| •Joseph Siravo | played | Carlos Sandoval (1999 - 2001) |
| •Roscoe Born | played | Peter Vreeland (2001) |
| •Paul Wasilewski | played | Max Nickerson (#2) (1999-2001) |
| •Terrell Tilford | played | David Grant #3 (1998-2001) |
| •Ryan Brown (1) | played | Harlan Billy "Bill" Lewis, III #2 (1998-2000) |
| •Amy Ecklund | played | Abby Blume Bauer (1995-2000) |
| •Bethany Joy Lenz | played | Michelle Bauer Santos #4 (1998-2000) |
| •Tammy Blanchard | played | Drew Jacobs (1997-2000) |
| •Timothy Adams | played | Rob Layne #2 (2000) |
| •Robert Lupone | played | Leo Flynn (1990; 1992 - 1996; 2000) |
| •Patti D'Arbanville | played | Selena Davis (1998-2000) |
| •Hayden Panettiere | played | Elizabeth 'Lizzie' Spaulding (#1) (1996 - 2000) |
| •Paulo Benedeti | played | Jesse Blue (1997 - 2000) |
| •Wendy Moniz | played | Dinah Marler Thorpe Jessup #3 (1995-1999) |
| •Frank Grillo | played | Hart Jessup (#5) (1996-1999) |
| •Tom Wiggin | played | Sam Kershaw (1999) |
| •Jesse Soffer | played | Max Nickerson (#1) (as Jesse Lee) (1999) |
| •Hunt Block | played | Ben Warren (#2) (1997-1999) |
| •Kimberly J. Brown (1) | played | Marah Lewis #4 (1993 - 1998) |
| •Jay Hammer | played | Fletcher Reade (1984-1998) |
| •Toby Poser | played | Amanda Spaulding Thorpe #2 (1995-1998) |
| •Bryan Buffington | played | Harlan Billy 'Bill' Lewis III #1 (1989-1998) |
| •Fiona Hutchison | played | Jenna Bradshaw Cooper (1992-1994, 1996-1998) |
| •Peter Hermann (1) | played | Michael Burke (1997-1998) |
| •William Bumiller | played | Sean McCullough (1998) |
| •Cynthia Watros | played | Annie Dutton Bauer Lewis (1994-1998) |
| •Geoffrey C. Ewing | played | Griffin Williams (1995 - 1998) |
| •Robert Gentry (3) | played | Dr. William "Ed" Bauer (#2, #7) (1966 - 1969; 1997 - 1998) |
| •Petronia Paley | played | Vivian Grant (1992 - 1997; 1998) |
| •Rebecca Budig | played | Michelle Bauer (#2) (1995-1998) |
| •Sharon Leal | played | Dahlia Crede (1996 - 1998) |
| •Johnny Messner | played | Rob Layne (#1) (1998) |
| •Melissa Hayden (1) | played | Bridget Reardon (1991-1997) |
| •Sonia Satra | played | Lucy Cooper Spaulding (1993-1997) |
| •Michael Zaslow | played | Roger Thorpe #1 (1971-1980, 1989-1997) |
| •Michael Tylo | played | Quint McCord Chamberlin #1 (1981 - 1986, 1996 - 1997) |
| •Jason Olive | played | Adrian 'Sugar' Hill (#1) (1997) |
| •Michael Dietz (1) | played | Alan-Michael Spaulding (#3) (1996-1997) |
| •Lisa Brown (1) | played | Nola Reardon Chamberlain (1980 - 1985; 1995 - 1997) |
| •Terrell Anthony | played | Rusty Shayne (1986 - 1989,1990,1996-97,1998, 1999, 2000, 2002) |
| •Nina Landey | played | Cassie Lawrence (1995-1996) |
| •Marc Wolf | played | Brent Lawrence #2 (1996) |
| •Frank Beaty | played | Brent Lawrence (1995-1996) |
| •Amelia Marshall | played | Gilly Grant Speakes (1989 - 1996) |
| •Rick Hearst (1) | played | Alan-Michael Spaulding (#2) (1990-1996) |
| •William Roerick | played | Dr. Bruce Banning (1974) / Henry Chamberlain (1980-1996) |
| •Vincent Irizarry | played | Lujack (Brandon) Luvonaczeck (1984 - 1986) / Nick McHenry Spaulding (1991 - 1996) |
| •Barbara Crampton | played | Melinda 'Mindy' Lewis (#4) (1993 - 1995) |
| •David Lee Russek | played | Christos (1995) |
| •Barbara Berjer | played | Barbara Norris (1971 - 1981; 1989; 1995-1996) |
| •Monti Sharp | played | David Grant (1992 - 1995) |
| •Russell Curry | played | David Grant (#2) (1995) |
| •Hilary Edson | played | Eve Guthrie (1992-1995) |
| •Marcy Walker | played | Tangie Hill (1993 - 1995) |
| •Joe Ponazecki | played | Lieutenant/Detective Larry Wyatt (1977 - 1983; 1987 - 1988; 1990 - 1991; 1994) |
| •Robert Milli | played | Adam Thorpe (#2) (1972-1981, 1989, 1994) |
| •Elizabeth Lawrence (1) | played | Bess Lowell (1993 - 1994) |
| •Lewis Arlt | played | Ross Marler (1993) |
| •Sherilyn Wolter | played | George (1993) |
| •Kevin McClatchy | played | Vinnie Morrison (1993) |
| •Mark Derwin | played | A.C. Mallett (aka Anthony Camaletti) (1990 - 1993) |
| •Roger Howarth | played | Jory Andros (1992) |
| •Tom Tammi | played | Jack Kiley (1992) |
| •Beverlee McKinsey | played | Alexander Spaulding (#1) (1984 - 1992) |
| •Kassie DePaiva | played | Chelsea Reardon (1986-1991) |
| •Lee Lawson (1) | played | Bea Reardon (1980-1987, 1990) |
| •Yvonne Perry | played | Brittany Wilding (1990) |
| •James Rebhorn | played | Bradley Raines (1983-1985, 1989) |
| •Ken LaRon | played | MacGregor (1989) |
| •Carl T. Evans | played | Alan-Michael Spaulding #1 (1987-1989) |
| •Paige Turco | played | Dinah Marler (#2) (1987-1989) |
| •Joseph Breen (1) | played | Dr. Will Jeffries (1987 - 1989) |
| •Daniel Pilon | played | Alan Spaulding (#2) (1988-1989) |
| •Alexandra Neil | played | Rose McClaren Shayne (1987 - 1988) |
| •John Cunningham (1) | played | Welles Carrera (1988) |
| •Alan North | played | Jack Bauer (1988) |
| •Ian Ziering | played | Cameron Stewart (1986 - 1988) |
| •Lawrence Weber | played | Clarence Bailey #1 (1982-1985, 1987) |
| •Lisby Larson | played | Calla Matthews (1985-1987) |
| •Jennifer Gatti | played | Dinah Marler #1 (1986-1987) |
| •Robin Ward | played | Paul Valere (1986-1987) |
| •Patricia Barry (1) | played | Sally Gleason (1984 - 1987) |
| •Larkin Malloy | played | Kyle Sampson (1984 - 1987) |
| •Jack Betts | played | Dr. Wilson Frost (1973 - 1974) / John Cutter (1987) |
| •Warren Burton | played | Warren Andrews (1983 - 1987) |
| •Ellen Dolan | played | Maureen Reardon Bauer #1 (1982-86) |
| •John Bolger | played | Phillip Spaulding (1985 - 1986) |
| •Richard Van Vleet | played | Dr. Edward "Ed" Bauer (#5) (1984 - 1986) |
| •Judi Evans Luciano | played | Beth Raines Bauer Spaulding Lemay Winslow (#1) (1983 - 1986) |
| •Victor Slezak | played | Andy Ferris (1984-1985) |
| •Michael Woods | played | Dr. James Reardon (1983 - 1985) |
| •Jack Armstrong (1) | played | Wally Bacon (#1) (1985) |
| •Annabelle Gurwitch | played | Gina Daniels (1984 - 1985) |
| •Keith Charles | played | Brandon Spaulding #3 (1984) |
| •John Wesley Shipp | played | Kelly Nelson (1980 - 1984) |
| •Giancarlo Esposito | played | Clay Tynan (1982-1983) |
| •John Wardwell | played | Brandon Spaulding #2 (1983) |
| •Kathleen Cullen | played | Amanda Spaulding #1 (1978-1983) |
| •Benjamin Hendrickson | played | Silas Crocker (1981 - 1983) |
| •Clement Fowler | played | Professor Martin Bruhner (1982 - 1983) |
| •Stephen Joyce | played | Eli Simms (1983) |
| •Rose Alaio | played | Helena Manzini (1981 - 1983) |
| •Geraldine Court | played | Jennifer Stafford/Richards (Jan 1980 - 1983) |
| •Harley Venton | played | Derek Colby (1981-1982) |
| •Charita Bauer | played | Bertha 'Bert' Miller Bauer (1952-1984) |
| •Jane Elliot | played | Carrie Todd Marler (1981 - 1982) |
| •Millette Alexander | played | Dr. Sara McIntyre Gantry Werner Blackford Thorpe (1969 - 1982) |
| •Christopher Marcantel | played | Tim 'TJ' Werner (1981 - 1982) |
| •Stephen Yates | played | Ben McFarren (1976 - 1982) |
| •Andreas Katsulas | played | Lucien Goff (1982) |
| •JoBeth Williams | played | Brandy Shelooe #2 (1977-1981) |
| •Ted LePlat | played | Andrew Norris #2 (1980-1981) |
| •Alan Austin | played | Carter Bowden (1979-1981) |
| •Kate Wilkinson | played | Viola Stapleton (1975 - 1981) |
| •Jennifer Leak | played | Blanche Bouvier (1981) |
| •Sofia Landon Geier | played | Diane Ballard (1977 - 1981) |
| •Anna Stuart | played | Vanessa Chamberlain (1980 - 1981) |
| •Lenore Kasdorf | played | Rita Stapleton Bauer (1975 - 1981) |
| •Curt Dawson | played | Peter Chapman (1978 - 1980) |
| •David Thomas | played | Brandon Spaulding #1 (1979) |
| •Maureen Mooney | played | Ann Jeffers (1975-1979) |
| •Peter Gallagher (1) | played | Chuck Haskell (1979) |
| •David Bailey (1) | played | Alan Spaulding (#2) (1979) |
| •Gordon Rigsby | played | Dean Blackford (1977-1978) |
| •Linda McCullough | played | Hillary Bauer (#1) (1977 - 1978) |
| •Robin Mattson | played | Hope Bauer (1976 - 1978) |
| •Sandy Faison | played | Brandy Shellooe (#1) (1977) |
| •Katherine Justice | played | Hope Bauer (1977) |
| •Barney McFadden | played | Andrew Norris #1 (1975) |
| •Caroline McWilliams | played | Janet Mason Norris (1969 - 1975) |
| •Nancy Addison Altman | played | Kit Vested (1970 - 1974) |
| •Fred J. Scollay (1) | played | Bertrand Mendel (1974) |
| •Melinda Fee | played | Charlotte Waring Bauer #2 (1970-1973) |
| •Marcus Smythe | played | Gordon Middleton (1978 - 1979) |
| •Elissa Leeds | played | Hope Bauer Spaulding (1968 - 1973) |
| •Barbara Rodell | played | Leslie Norris Bauer (1971 - 1973) |
| •Graham Jarvis | played | Charles Eiler (1971-1972) |
| •Madeleine Sherwood | played | Betty Eiler (1971-1972) |
| •Robert Gerringer | played | Adam Thorpe #1 (1972) |
| •Ed Zimmermann | played | Joseph Werner #2 (1967-1972) |
| •Theo Goetz | played | Frederick 'Papa' Bauer (1952-1972) |
| •Rosetta LeNoire | played | Leona Herbert (1971 - 1972) |
| •Berkeley Harris | played | Joseph 'Joe' Werner (#3) (1972) |
| •Christina Pickles | played | Linell Conway (1970 - 1972) |
| •Kate Harrington | played | Marion Conway (1971 - 1972) |
| •Sydney Walker | played | Bruce Banning #3 (1970-1971) |
| •Courtney Sherman | played | Dinah Buckley (1970-1971) |
| •Kathryn Hays (1) | played | Leslie Jackson (1971) |
| •William Smithers | played | Stanley 'Stan' Norris (#2) (1971) |
| •Augusta Dabney | played | Barbara Norris (1970) |
| •Victoria Wyndham | played | Charlotte Waring Fletcher Bauer (aka Tracy Delmar) (#1) (1967-1970) |
| •Ed Bryce | played | William 'Bill' Bauer (#2) (1959 - 1963; 1965 - 1969; 1977 - 1978; 1983) |
| •Christopher Wines | played | Marty Dillman (#2) (1968 - 1969) |
| •Bernard Kates | played | Ben Scott (1965-1968) |
| •Philip Sterling | played | George Hayes (1963 - 1968) |
| •Don Scardino | played | Johnny Fletcher (1965 - 1967) |
| •Gillian Spencer | played | Robin Lang Bauer Bowden Fletcher (#6) (1964 - 1967) |
| •Billy Dee Williams | played | Jim Frazier (#1) (1966) |
| •Barnard Hughes | played | Dr. Bruce Banning (#2) (1961 - 1966) |
| •Ernest Graves | played | Alex Bowden (1960 - 1966) |
| •Ellen Weston | played | Robin Lang Holden Fletcher (#5) (1963 - 1964) |
| •Kay Campbell (1) | played | Helene Benedict (1957 - 1964) |
| •Barbara Becker | played | Doris Crandall (1961-1962) |
| •James Lipton | played | Dick Grant (1952-1962) |
| •Les Damon | played | Bruce Banning #1 (1956-1960) |
| •Dana Elcar (1) | played | Andrew Murray (1962) |
| •Elizabeth Hubbard | played | Anne Fletcher (1962) |
| •Lin Pierson | played | Alice Holden #3 (1958-1960) |
| •Joseph Campanella | played | Joe Turino (1959 - 1960) |
| •Lyle Sudrow | played | Bill Bauer #1 (1952-1959) |
| •Diane Gentner | played | Alice Holden #2 (1956-1958) |
| •Sandy Dennis (1) | played | Alice Holden #1 (1956) |
| •Glenn Walken | played | Mike Bauer #1 (1954-1956) |
| •Ruth Warrick | played | Janet Johnson (1953 - 1954) |
| •Charles Baxter | played | John Brooks, M.D (1954) |
| •Richard Holland (1) | played | Joey Roberts (1953) |
| •Helen Wagner | played | Trudy Bauer (1952) |
