Marshal Dillon befriends a young man, Cale, who has earned his respect. But Tate Gifford believes Cale has stolen his horse.
A teenage girl who escaped from an abusive situation at an orphanage, leads to Matt's discovery of the true happenings of what is going on there.
Quint Asper is an angry half-breed Indian, who has hatred towards the white man after his father is killed. Years later as a Comanche, he returns and takes Matt prisoner and is told to kill him by his chief.
Aggie Dutton has come into Dodge City with the intension of finding a man. Her choice is Chester, whether he is willing or not.
When a bank robber and his girl come to Dodge City, Matt is made the target after the thief is arrested for killing a man who beat him out of $1,000 at poker.
A cattle thief, Collie, is released from prison after eight long years and wants his revenge against Marshal Matt Dillon.
A woman keeps her deceased father's plan alive to divert the water supply away from the homesteaders. It's up to Matt to keep the peace and find a solution when the homesteaders band as one to fight the blockade.
When a pair of fur trappers roam into Dodge City, Matt fears they should leave before some greedy criminal goes after the money the furs should fetch.
Phoebe Strunk and her boys ride into Dodge after robbing and burning a couple in their wagon. Annie recognizes the wagon as belonging to her parent's. The boys plan on keeping her quiet, even if it means killing again.
The wife of an abusive man and her equally mean streaked son, asks Matt to rescue her daughter from their home and keep her safe from her family.
A crazed mountain man, Abe Blocker, starts a killing spree around the territory. As a posse tracks him down hiding in the mountains, Abe uses his knowledge of the hills to his advantage.
While Matt is away on business, Kitty falls for a man, unaware he has an anger problem. She doesn't find this fact out until she invites him to the Ford County Sociable.
Matt's new companion, Festus Haggen, is on the trail of his uncle, who is accused of shooting his twin brother dead.
A letter from Chester's uncle Sunday, has him searching for extra work as to send money to him. A surprise visit to Dodge with niece Ellie, reveals that they plan on a bank heist, and she then figures on leaving Uncle Sunday for another man. Can Chester stop the robbery before his relative becomes a wanted man?
A man attempts to win a bet by coming into Dodge under a false reputation of being a gunslinger, and leaving without a confrontation. But when a youngster hears of this tough shooter, he plans on making his own reputation by beating him to the draw.
A half-breed Indian son of a General is a wanted man. As Matt arrives to tell them he is no longer wanted he discovers the young man has fled. Catching up to him back at his home, the General feels apologetic for leaving his son and mother behind.
Clara is married to Bart but is in love with his best friend Murph. Bart drowns a man who Clara claims forced her to drink with him, unaware that Louis Pheeters saw the crime. But it's Louie who is accused of the crime, that is until Murph is caught with Clara by Bart.
Quint comes to the rescue of a bigoted woman who is caught in the middle of a stagecoach ambush.
Matt is left in charge of a young woman when her father is beaten to death. The woman, ,is to be brought to her Aunt's home in Harrisburg, but Matt and Kitty attempt to make her a bit more civilized first.
A young woman may be the witness to a stage coach hold up, but refuses to identify the suspect after having been kissed by him after the robbery.
Chance Hopper has been released from prison after serving for a hold up. Chance and Matt just happen to have been raised by the same parents, but Matt is weary of him because of his past. But it is up to Chance to prove his loyalty when Matt goes after his two former partners in crime.
Shona, an Indian woman and friend of Quint, is in need of protection when the sons of a man killed by Indians want their revenge against Shona and her white husband, who's tracks lead to the murder scene.
Two men vie for the same woman, Tillie, a saloon girl at the Long Branch. But both are out of luck when her fiance intervenes. The men become partners in a freight business, but one is injured by a falling barrel. When he awakens the man has a different personality, one in which brings him back to Tillie and may lead to his death.
A man, Billy Poe, is made a wanted man after a dying man accuses him as his killer. While searching for Billy, Matt is knocked unconscious by three men with a hatred for the law. A blurry eyed Matt can barely make out the man who is assisting him as Billy.
Quint is accused of stealing a horse that he was paid to shoe. While Matt attempts to clear his friend's name, he himself is accused by a group of Indians of informing the cavalry to their whereabouts.
A man, believing he had killed Matt, becomes obsessed when he realizes Dillon is still alive and well in Dodge. Now he is on a quest to make sure he kills the Marshal, once and for all.
Two men, Sean and Tim, arguing over a woman end up coming to each other's aid when a man attempts to claim a salt mine that exists on both their properties.
The folks in Dodge City don't take to kindly to Jud Sorrell, a cowpoke, who has just taken in a homeless Indian boy he calls Wonder.
Dal Creed falls for Lottie, a woman who's father he killed. But she has her eyes on Pat Kane, a man who Dal framed and had fired by Lottie's father. But when Lottie and Pat's relationship is found out by Dal, one of them will be murdered and Dal will be sentenced to hang.
When Jeff Newcom is sent away to Chicago by his mother, little did he know that his girl would not be waiting for his return. Upon his return, Millie informs him that she is involved with another man. Jeff refuses to let her go, but little does he know it is Ma Newcom who has caused the rift in their relationship.
Pan Sykes comes to Dodge City to get a return favor from Kitty, who she had lived with for two years after her mother passed away. The problem is, Pan is a wanted pickpocket who has roamed all across the country.
Chester is accused of killing a woman he once loved, after she marries another man and then becomes deathly ill. When her husband sees Chester burying her body, her husband hires a gunman to shoot him down.
A widow is the only person who can free Quint after she is the victim of an assault.
Matt meets up with two men who held him hostage seventeen years earlier, after robbing a bank and was to have been executed.
Chester falls in love with Lucy Damon, a woman who claims that her husband had died. But Chester wants to know the truth when he finds her husband fishing on a river.
A former Army guard comes to the aid of a lovely woman who was in danger of being killed, after the brother of her dead fiance blames her for his death.
A young man, Jeb, is accused of murder when he shows up riding a horse that belonged to the dead man. It's up to Matt to intervene and find out who killed the buffalo hunter.
Matt gets caught between a man accused of killing Lucy Furth, the real murderer and Lucy's husband, who plans to get his revenge for his wife's death.