12-year-old Adam Lyon becomes the only human student at Charles Darwin Middle School, where the animal inhabitants of the local zoo and aquarium send their kids. With signs that warn, “Do Not Eat the Other Students,” Adam has his hands full just making it through middle school alive.

Ever since a typo mix-up that involved switching the last name, Lyon to Lion, a 12 year old boy named Adam Lyon was accidentally put in a school called Charles Darwin Middle School, which is an all-animal school where the parents of the animal children of a local zoo and aquarium send the children to, making Adam the only student that is actually a human.

Charles Darwin Middle School is like the rain forest because the school supplies animals of all kinds living in harmony in their surroundings. The monkeys and chimpanzees surround the hallways by vines or swinging on tires between their classes. Underwater hallways run the length of the school where the aquatic creatures travel. Around the school, the birds fly freely.

Even in only one day, Adam has to worry about being alive because of the warning signs that say, "Do not eat the other students." Adam is always the last one to be picked in gym class. He must always try to fit in with all the animals, like gorillas, giraffes, snakes, birds, fish and bats. Every single class is like a challenge for the human who is alone. It's even tougher when you have Tyson, a bull shark who waits for Adam in a toilet. When Adam and Jake Spider Monkey meet they become friends fast, but Adam discovers having a monkey as a best friend can be as crazy as it is fun.

A few years ago, a friend of Julie McNally Cahill and Tim Cahill mentioned how he used to spend time with a monkey at an alternative school as part of growing up. They were inspired to pitch again after pitching their first animated cartoon called Carrotblanca. This is where the concept of My Gym Partner's a Monkey came from, which they passing to Cartoon Network. They also were pitching a more elaborate idea. Cartoon Network chose the elaborate idea, the idea in which this show is about.

Theme Song
I used to go to a normal school where everyone was the same
but now I go to an animal school 'cause Lyon's my last name

My Gym Partner's a Monkey
(Monkey Monkey Monkey!)
My Gym Partner's a Monkey
(Monkey Monkey Monkey!)

Bull shark, porcupine, I don't know what,
Going to this school's a pain in the---

(Adam!
What? I was going to say neck!
Oh. That's okay then.)

My Gym Partner's a Monkey
(Monkey Monkey Monkey)
My Gym Partner's a Monkey
(Monkey Monkey Monkey)
My Gym Partner's a Monkey
(MONKEY, MONKEY, MONKEY)
My Gym Partner's a Monkey!