Will consults on a case where victims' faces have been mangled into a "Glasgow Smile". Unfortunately, his time lapses get worse, causing him to contaminate the crime scene and actually wonder if he himself is the killer. A brain scan reveals that Will has Advanced Encephalitis. Hannibal, seeing an opportunity, intimidates Dr. Donald Sutcliffe into lying to Will about his illness. When Sutcliffe himself is then murdered, Will becomes the prime suspect.