Santiago Cabrera (Isaac Mendez) and Tawny Cypress (Simone Deveaux) do not appear in this episode. Sendhil Ramamurthy (Mohinder Suresh) appears in a flashback to "Homecoming", but does not appear in any new scenes.

Symbols: An eclipse appears in reflected light at the hospital.

The date is April 24th - Charlie's birthday.

Sylar's real name is Gabriel Gray.

Niki's dead sister, Jessica, was born in 1976 and died in 1987.

According to Greg Beeman's blog, the first 1000 cranes used for the episode were made by a Catholic girls' school. The remaining cranes needed were made by 10 people working 8 hours for 3 days.

Ratings: 15.56 million viewers

Mohinder: (opening voiceover) To every thing, there is a season and a time to every purpose. The Earth spins at a thousand miles an hour as we desperately try to keep from being thrown off. Like the first blush of winter that signals the great migration. Is there any warning of their arrival? A sign? A single event that set this chain into motion? Was it a whisper in God's ear? Survive, adapt, escape. And if we could mark that single moment in time, that first hint of the prophecy of approaching danger. Would we have done anything differently? Could it have been stopped? Was the die long ago cast? And if we could go back, alter its course, stop it from happening, would we?

Hiro: (to Charlie) My name is Hiro Nakamura. I'm here to save your life!

Gabriel Gray: You didn't come here for the watch.
Chandra Suresh: I came to find you, Gabriel. My name is Chandra Suresh, I'm a geneticist. I have a theory about human evolution and I believe you are a part of it. Read it, if you'd like to talk more, I've written my phone number and address inside.

Matt: License and registration?
Eden McCain: Oh, this isn't my car, I kinda stole it.
Matt: Can you take off your glasses for me, please? I'm gonna have to ask you to step outta the car.
Eden McCain: No, I don't feel like it.
Matt: That wasn't a suggestion.
Eden McCain: Well, here's a suggestion. Why don't you go get back in your car and eat a dozen donuts? That is what you cops like to do, right?
Matt: I said step outta the car. Now!
Eden McCain: I think you really want to eat some donuts.

Jackie: Major developments! Lori Tremmel skanked her way through the entire football team.
Claire:Who told you that?
Jackie: The entire football team.

Hiro: Six months? I've got to get back. If I teleport again I could end up anywhere. Lunch for a T-Rex! I'm stuck!

Niki: (to Hal) You weren't awful, you just weren't there. You can't be awful if you're not present.

Chandra Suresh: The brain controls every human action, voluntary or involuntary. Every breath, every heartbeat, every emotion. If the soul exists, scientifically speaking, it exists in the brain.
Gabriel Gray: When I was a kid, I used to wish some stranger would come and tell me my family wasn't really my family. They weren't bad people, they were just... insignificant... and I wanted to be different. Special, I wanted to change, a new name, a new life. The watchmaker's son became a watchmaker. It is so futile... that I wanted to be important.
Chandra Suresh: You are important, Gabriel.

Eden McCain: Let me go, now!
Mr. Bennet: You know, with your ability, you can get anything you want. Created your own morality, there's no person in the world that can say no to you. Now there is.

Charlie: Lately, I've just been able to remember everything.
Hiro: You have power - big memory. It will only get stronger in the future.
Charlie: The future, right. I keep forgetting that's where you come from.
Hiro: You don't believe me? I bend time and space.
Charlie: Oh, yeah, of course you do.

Peter: I had a dream right before you called.
Nathan: My wife's in surgery and you're dreaming. That's great.

Mr. Bennet: If you do figure this out, what happens then?
Chandra Suresh: We can change the world. Give people hope for the future. That is your daughter's destiny.

Jessica: Niki doesn't remember but I do. Someone had to be there to protect her. I remember the stink of alcohol on your breath, I took every punch so that she wouldn't have to.
Hal: You're not Jessica.
Jessica: You have no idea who I am.

Claire: Am I a terrible person?
Mr. Bennet: What are you talking about?
Claire: I wanna be a cheerleader, I mean, I've worked hard to be a cheerleader but sometimes Jackie can just be a...
Mr. Bennet: A bitch?
Claire: Yeah, a bitch.

Janice Parkman: You are everything that I want.
Matt: I'm a hero. I'm a hero.

Nathan: (to Peter) Dad's dead. He had a heart attack this morning. Should take comfort in the fact that he didn't know his sons were about to stab him in the back.

Hiro: You still do want to go?
Charlie: Yeah. Oh, yeah, no, it's not that, it's just, um, ever since I met you, I don't know, you just make me so happy.
Hiro: You make me happy, too.
Charlie: Well, it's more than that. I don't let people get very close. There's a blood clot in my brain, inches away from an aneurysm. I'm dying.
Hiro: But... I'm supposed to save you.
Charlie: You did... you did. Before you got here, I decided to give up. But you have made me feel more alive and more full of joy than I could have ever imagined. Hiro... (in Japanese) I love you.

Hiro: Charlie? No... Charlie? CHARLIE? CHARLIE?
Worker: Hiro? Aren't you and Ando supposed to be on vacation in America?
Hiro: I jumped. Dammit!

Sylar: (to Brian Davis) My name is... (looks at watch) my name is Sylar. I'm Gabriel Sylar.

Gabriel Gray: You're broken.
Brian Davis: What?
Gabriel Gray: Suresh was right, it's so clear now. How it all works, pieces fitting together, it is in the brain.
Brian Davis: So, you can help?
Gabriel Gray: Don't worry, Brian, I can fix it. It's an evolutionary imperative.

Gabriel Gray: Well, I'm different now. I feel I've been given a chance to start over. New life, a new identity, new purpose.

Hiro: I couldn't save Charlie.
Ando: So, try again.
Hiro: It won't work. This power... it's bigger than me. I can't change the past. No matter how hard I wish.

Mohinder: (closing voiceover) This list, these people, their futures written on their DNA, just as the past it seems is written in stone. Was the die cast from the very beginning? Or is it in our own hands to alter the course of destiny? Of all our abilities, it is free will that truly makes us unique. With it, we have a tiny but potent chance to deny fate. And only with it, can we find our way back to being human.

Hiro invites Charlie to a 24-hour samurai-film festival at the Drafthouse in Austin. However, Alamo Drafthouse Cinema doesn't host a samurai film festival.

During the party for Peter, the song "Smile" by Lily Allen is played. However, the song was released in September 2006, which is later than when this episode is said to take place.

When Nathan levitates away from the car, you can still see someone in the driver's seat.

Hiro: Great Scott!

This expression is used by Doc Brown in the Back To The Future films.

Mohinder: (opening voiceover) To everything there is a season, and a time to every purpose.

Mohinder is quoting a line from the Biblical book of Ecclesiastes 3:1.

At the clock shop, the clock behind Brian Davis and Sylar shows the time as seven minutes to midnight, a direct reference to "Seven Minutes to Midnight".