Malick attempts to come to terms with his injury. Elliot is not happy after Zosia proves to be a handful. Sacha feels like he has no choice but to tell Chrissie the truth about what happened between him and Mo.
Harry finds himself on the wrong side of Gemma after an old friend turns up on AAU. Mo’s day ends up going from bad to worse after the men in her life cause her to question her choices in her life.
Songs: Daft Punk -- Get Lucky
Chantelle looks for the comfort her job offers her as she returns to work, only for her expectations to be challenged straight away. Zosia speaks out of turn as she treats a patient suffering with heart disease.
Malick is attempting to adjust to a new career outside of the operating theatre. Sacha and Chrissie decide to renew their vows after she is given the all-clear, only to consider if they can actually live up to the decision.
Chantelle has to face her worst nightmare as her relationship with Arthur takes a dramatic turn. Mo's dalliance with Joey threatens her future. Chrissie ends up finding comfort in the arms of a friend.
Chrissie needs to look inside herself to discover what she truly needs. Arthur finds it hard to cope as Malick spirals out of control.
Malick reaches breaking point. Serena's world ends up being turned upside down after a new face shows up at the hospital. Jonny and Bonnie decide to teach Zosia a lesson after she refuses to be part of the team.
Guy wants to make a fresh start, but after his past follows him to the hospital; it might be difficult.Jac and Jonny find it hard to deal with some difficult news.
Mary-Claire has a fight on her hands after she goes up against Edward. Elliot lets flattery get the better of him after he agrees to do an operation.
Michael ends up putting his career on the line when he has to deal with a heartbreaking case. Gemma makes a difficult decision about her future at the hospital. Zosia's secret is finally exposed.
Serena and Edward show up for work all loved-up and there could be trouble ahead for them. Mo attempts to find the courage to take the Christmas gift that has been in front of her for so long.
Guy tries to rebuild his relationship with Zosia as just a couple of professionals working together. Serena puts on a brave face following Edward's betrayal. Mary-Claire finds it hard to forgive Harry.
Jac's delivery date comes closer and after she begins to experience contractions early, she panics and the team on Darwin are called into action. Following a traumatic Christmas break, Serena returns determined to start afresh.
Colette comes under some professional scrutiny. A controversial figure from the past returns to the hospital, and Jac and Jonny find it hard to cope as their baby's life hangs in the balance.
Emma is about to have her surgery as Jac attempts to defeat her demons and be there to support her daughter. Arthur and Dominic continue to clash with some potentially disastrous consequences.
A new registrar on AAU is determined to revolutionise the ward. After a patient shows up in a critical condition and the hospital lacks a vital piece of equipment necessary to save him, he decides to create his own version.
Sacha continues to put the students through a punishing teaching schedule. Arthur starts to allow his Doctor of the Year award go to his head and Dominic decides to take his rival down a peg or two. Serena is not happy at being sent to cover AAU, but after an intriguing patient presents a business opportunity, she believes that she could have finally found a way to prove her value to Guy.
Jonny is upset after Jac risks being late for Emma's christening to help Elliot operate on a patient suffering with a rare heart condition. a man with an abscess in his rectum refuses to be operated on by a woman.
Zosia is happy after Sacha finally offers her the chance to prove herself with a challenging patient but things end up taking a catastrophic turn. Jonny is shocked after Jac suggests that her position gives her the right to make decisions concerning their daughter.
Jonny begins his first shift as clinical nursing manager on Darwin and has to deal with a couple of runaway teenagers. He also needs to find time to save the life a vulnerable patient.
Beth is still in a coma and Guy is determined to try and boost the Tressler Neurosurgical Foundation's profile. Dominic is determined to prove himself after showing up late for work.
Jess gets ready to undergo surgery as Ric finds it hard to step back as a doctor and let Serena deal with the case. Guy is feeling under pressure following the withdrawal of the Tressler fund.
Guy has to face the hospital board after Zosia backs a complaint against him. But she starts to crumble after it seems that the CEO is more interested in protecting his daughter's career than his own. Ric is also in big trouble after covering for Jess's part in the hit-and-run.
A new consultant pharmacist called Amy catches Harry's eye but they soon clash over the best way to treat a patient. Jac refuses to play happy families but after events spiral out of control during the hen party, Jonny decides that enough is enough.
Jonny and Bonnie's wedding day arrives but he still has lots of things to do before he's ready to get married. Zosia finds it hard to cope on the anniversary of her mother's death. Serena becomes obsessed with the new patient satisfaction surveys as she attempts to impress Connie.
Harry is excited to receive an invitation to an exclusive black-tie event, only to be put out when he discovers that not only is arch-rival Raf the keynote speaker but his wife Amy is now permanent consultant pharmacist on the ward. However, he is intrigued to learn their marriage is not quite as perfect as it appears. Dominic offends Zosia while carrying out a difficult task for Sacha, and goes all out to win back her friendship, and Jonny returns to work after the wedding, furious with Jac over her behaviour at the ceremony. Can they possibly clear the air?
Source: BBC one
Raf and Amy learn whether their final round of IVF treatment has been a success. Dominic has a blast from the past. Elliot attempts to sort things out between Jonny and Jac after the tensions between them spill over into the ward.
The custody battle goes on as Jac plays dirty twisting Jonny's words and setting her lawyer against him. Arthur attempts to impress Guy and new anaesthetist Jesse.
Raf and Amy's relationship in under real pressure which results in a heart-wrenching betrayal. Jac finds the going tough as her past threatens to repeat itself.
Zosia is determined to show Sacha that she still has what it takes to pass her F1 year. Jonny finds an unlikely ally in the custody battle, unaware that Jac's mum can not be trusted.
Sacha manages to deal with Zosia and Arthur's concerns about a patient with a suspicious past but ends up suffering with a crisis of conscience after being faced with a shocking truth. An incident at the hospital sees Jonny and Jac being brought closer together as parents.
Serena has been really busy recently whilst trying to care for her mother, Adrienne. After Guy requests an urgent report outlining the hospital's chances of becoming a Neurosurgical Feeder Centre she's stretched to her limits. Elliot hasn't been feeling himself and keeps forgetting important things.
Amy is finally able to get what she has always wanted, only to realise that escaping the mistakes she has made with Harry is not quite that simple. Adrienne pays another visit to the hospital, only to be the cause a near-fatal accident.
Amy is trying to stay out of the tension between Raf and Harry. Guy realises the effect that Harry is having a bad effect on her and suggests transferring one of them. Mo rethinks things when a starstruck patient turns violent. Zosia is told to improve her bedside manner.
Amy is determined to make Harry shine until a crisis ruins all her hard work. Jac's childcare nightmare gets worse after Elliot lends a hand.
Songs: Dean Martin -- Ain't That a Kick in the Head
Jac and Jonny are preparing themselves for their day in court and are both determined to win custody of Emma. However Jac's past comes back to haunt her, when Paula proves she can still tie her in knots. Sacha doesn't believe things can get any worse, now his divorce has been finalised and he's back living with his mum. However a front page story hits the shelves, stating he's treated a Nazi war criminal and he finds himself going to Essie's aid.
Amy's hearing is about to get underway with Serena. Raf begins to feel uneasy after he realises her story contradicts that of Harry. Raf confronts Harry while they operate on a patient in theatre. Elliot manages to find a kindred spirit draws on this experience to find the courage to confront his own medical symptoms.
Raf is not impressed after having found out that pregnant wife Amy cheated on him with Harry and he demands that she takes a paternity test. Colette's warning has managed to hit a nerve with Jesse.
Jesse is offered a permanant post at Holby whilst Johnnie considers leaving Holby to look after Emma in Glasgow.
Elliot is still concerned about his undiagnosed illness, and as the start of the Herzig arrives, he hopes he can get through it without any problems. After he freezes in theatre, he faces not only losing his life's work, but also the potentially shocking truth of what's wrong with him.