Raf has to try and step up his game on the AAU. Michael Spence returns to town. Fleur Fanshawe shakes things up on Keller Ward, leaving Sacha feeling undermined.
Guy finds himself trying to get Jac on his side as Raf has a patient requiring complex surgery.
Mo becomes determined to prove that she can swim with the sharks. Serena’s personal and professional lives clash after her mother is brought in for treatment.
Colette starts to consider her future as Jesse gets a place on the research team.
Jesse manages to impress Mo with his teamwork as Serena's mother can no longer recognise her.
Michael's stay in Holby is coming to an end as he tries to stay longer as Adele has trouble with time-keeping.
Adrienne's funeral is taking place as Raf provides Serena with support as Zosia's behaviour continues to go downhill.
As Jesse realises what his fling with Zosia has caused, AAU faces cuts.
Raf feels thrown after Amy has an unexpected request. Dominic ruthlessly risks everything to fulfil his ambitions.
Zosia finds herself becoming emotionally involved with a patient and there are some catastrophic consequences. Mo is advised to follow her heart.
Elliot’s wishes a quiet family Christmas do not go to plan following the arrival of a friend in need. Arthur has step up after those around him begin to fall apart. Ric returns to AAU and ends up treading on quite a few toes.
Dominic’s past comes back to haunt him. Mo needs to find a date for her sister’s wedding. Harry helps Raf see in the New Year.
A family wedding uncovers a family secret as a familiar face rocks Guy's world.
Sacha's daughter arrives as a patient in need of treatment as Jac considers a new start with Emma.