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| •James McKenna (2) | played | Jack Osborne (2003-present) |
| •Helen Pearson | played | Frankie Dean Osborne (2002-present) |
| •Ashley Taylor Dawson | played | Darren Osborne (1999-2001, 2003-present) |
| •Nick Pickard | played | Tony Hutchinson (1995-2008, 2009-present) |
| •Carley Stenson | played | Steph Cunningham (2000-present) |
| •Ellis Hollins | played | Tom Cunningham (2004-present) |
| •Stephanie Waring | played | Cindy Cunningham #2 (1996-2001, 2004, 2008-present) |
| •Stuart Manning | played | Russell Owen (2004-present) |
| •Loui Batley | played | Sarah Barnes (2005-present) |
| •Tony Hirst | played | Mike Barnes (2005-present) |
| •Ashley Slanina-Davies | played | Amy Barnes (2005-present) |
| •Nicole Barber-Lane | played | Myra McQueen (2006-present) |
| •Hollie-Jay Bowes | played | Michaela McQueen (2005-present) |
| •Claire Cooper | played | Jaqui McQueen (2006-present) |
| •Jennifer Metcalfe | played | Mercedes McQueen Fisher (2006-present) |
| •Jamie Lomas | played | Warren Fox (2006-present) |
| •Gerard McCarthy | played | Kris Fisher (2006 -present) |
| •Gemma Merna | played | Carmel McQueen Valentine (2006-present) |
| •Ricky Whittle | played | Calvin Valentine (2006-present) |
| •Nathalie Emmanuel | played | Sasha Valentine (2006-present) |
| •Brian Bovell | played | Leo Valentine (2006-present) |
| •John Pickard | played | Dominic Reilly (2005-present) |
| •Andrew Moss | played | Rhys Ashworth (2005-present) |
| •Sonny Flood | played | Josh Ashworth (2005-present) |
| •Anthony Quinlan | played | Gilly Roach (2005-present) |
| •Chris Fountain | played | Justin Burton (2003-present) |
| •Jessica Fox (1) | played | Nancy Hayton (2005-present) |
| •Kieron Richardson | played | Steve Hay (2006-present) |
| •Zoe Lister (1) | played | Zoe Carpenter (2006-present) |
| •Garnon Davies | played | Eliot Bevan (2007-present) |
| •Samantha Giles | played | Valerie Holden (2008-present) |
| •Nico Mirallegro | played | Barry "Newt" Newton (2007-present) |
| •Stephen Uppal | played | Ravi Roy (2008-present) |
| •Lena Kaur | played | Leila Roy (2008-present) |
| •Nila Aalia | played | Bel Roy (2008-present) |
| •Antony Bunsee | played | Govinda Roy (2008-present) |
| •Saira Choudry | played | Anita Roy (2008-present) |
| •Junade Khan | played | Ash Roy (2008-present) |
| •Stephen Beard | played | Archie Carpenter (2008-present) |
| •Jorgie Porter | played | Theresa McQueen (2008-present) |
| •Kelly Marie Stewart | played | Hayley Ramsey (2009-present) |
| •Lorna Pegler | played | Emily Taylor (1999-2000) |
| •Emma Rigby | played | Hannah Ashworth (2005-2009) |
| •Barry Sloane | played | Niall Rafferty (2007-2008) |
| •Darren Jeffries | played | Sam 'OB' O'Brien (1997-2008) |
| •Devon Anderson | played | Sonny Valentine (2006-2008) |
| •Jake Hendriks | played | Kieron O'Dowd (2008) |
| •James Sutton | played | John-Paul McQueen (2006-2008) |
| •John Jardine | played | Bill Ashworth (2005-2008) |
| •Kevin Sacre | played | Jacob 'Jake' Dean (2002-2008) |
| •Leah Hackett | played | Tina McQueen Reilly (2006-2008) |
| •Matt Littler | played | Max Cunningham (1997-2008) |
| •Oliver Farnworth | played | Will Hackett (2006-2008) |
| •Quentin Jones | played | Roger Kiddle (2008) |
| •Roxanne Mckee | played | Louise Summers (2005-2008) |
| •Sam Darbyshire | played | Jamie 'Fletch' Fletcher (2005-2008) |
| •Sarah Jane Buckley | played | Kathy Barnes (2005-2008) |
| •Sinead Moynihan | played | Beth Clement (2007-2008) |
| •Ali Bastian | played | Becca Hayton Dean (2001-2007) |
| •Andrée Bernard | played | Liz Burton Taylor (2003-2007) |
| •Gemma Bissix | played | Clare Cunningham (2005-2007) |
| •Guy Burnet | played | Craig Dean (2002-2007) |
| •Jennifer Bidall | played | Jessica Harris (2005-2007) |
| •Sarah Dunn | played | Mandy Richardson Hutchinson (1997-2007) |
| •Cassie Powney | played | Melanie Burton (2003-2006) |
| •Ciara Janson | played | Nicole Owen (2004-2006) |
| •Connie Powney | played | Sophie Burton (2003-2006) |
| •David Prosho | played | Rob Owen (2005-2006) |
| •Greg Kelly (1) | played | Freddy Watson (2005-2006) |
| •Jaq Croft | played | Carrie Owen (2004-2006) |
| •Louis Tamone | played | Sam 'Liam' Owen (2004-2006) |
| •Matt Milburn | played | Joe Spencer (2003-2006) |
| •Rochelle Gadd | played | Olivia Johnson (2005-2006) |
| •Simon Cole | played | Jeremy Peterson (2005-2006) |
| •Alex Carter (2) | played | Lee Hunter (2001-2005) |
| •Ben Gerrard (2) | played | Cameron Clark (2002-2005) |
| •Christina Baily (1) | played | Dannii Carbone (2004-2005) |
| •Colin Wells (2) | played | Johnno Dean (2003-2004, 2005) |
| •Dan Cryer | played | Stu Harding (2004-2005) |
| •Gemma Atkinson | played | Lisa Hunter (2001-2005) |
| •John Graham Davies (1) | played | Les Hunter (2001-2005) |
| •Katherine Dow Blyton | played | Sally Hunter (2001-2005) |
| •Kelly Greenwood | played | Zara Morgan (1999-2005) |
| •Kent Riley | played | Zak Barnes (2004-2005) |
| •Kim Bourelle | played | Bella Manning (2004-2005) |
| •Lee Otway | played | David 'Bombhead' Burke (2001-2005) |
| •Marcus Patric | played | Ben Davies (2000-2005) |
| •Richard Calkin | played | Richard Taylor (2003-2005) |
| •Sarah Baxendale | played | Ellie Hunter Mills (2002-2005) |
| •Stevie Caffery (1) | played | Michelle (2005) |
| •Andrew Newton-Lee | played | Robbie Flynn (2003-2004) |
| •Andy McNair | played | Dan Hunter (2001-2004) |
| •Bernard Latham | played | Gordon Cunningham (1995-2004) |
| •Christian Ealey | played | Matt Musgrove (2000-2003, 2004) |
| •Daniel Hyde | played | Scott Anderson (2001-2004) |
| •Darren Bransford | played | Nick O'Connor (2001-2004) |
| •Elize du Toit | played | Izzy Cornwell Davies (2000-2004) |
| •Georgina Redhead | played | Emma Chambers (2003-2004) |
| •Helen Noble | played | Abby Davies (2000-2004) |
| •Jamie Luke | played | Norman Sankofa (2001-2004) |
| •Jodi Albert | played | Debbie Dean (2002-2004) |
| •Kathryn George | played | Helen Richardson Cunningham (1997-2004) |
| •Max Brown | played | Kristian Hargreaves (2002-2004) |
| •Mikyla Dodd | played | Chloe Bruce (2000-2004) |
| •Sarah Lawrence | played | Darlene Taylor (2003-2004) |
| •Terri Dwyer | played | Ruth Osborne Benson (1995-2001, 2003-2004) |
| •Tiffany Mulheron | played | Natalie Osborne (2003-2004) |
| •Henry Luxemburg | played | Toby Mills (2001-2003) |
| •Jonathan Le Billon | played | Brian Drake (2001-2003) |
| •Kate McEnery | played | Jodie Nash (2001-2003) |
| •Natasha Lund | played | Eve Crawford (2001-2003) |
| •Andrew Somerville | played | Theo Sankofa (2001-2002) |
| •Gary Lucy | played | Luke Morgan (1999-2001, 2002) |
| •James Redmond | played | Rory 'Finn' Finnigan (1997-2002) |
| •Julie Buckfield | played | Julie Matthews (1995-1997, 2002) |
| •Lisa Kay | played | Anna Green (1999-2002) |
| •Martino Lazzeri | played | Alex Bell (1999-2002) |
| •Ross Davidson (1) | played | Andy Morgan (1999-2002) |
| •Sarah Jayne Steed | played | Alyson Turner (2001-2002) |
| •Stefan Booth | played | Jamie Nash (2001-2002) |
| •Ben Hull | played | Lewis Richardson (1997-2001) |
| •Colin Parry | played | Mark Gibbs (2000-2001) |
| •Dannielle Brent (1) | played | Gina Patrick (1997-2001) |
| •Fiona Mollison | played | Victoria Hutchinson (2000-2001) |
| •Joanna Taylor | played | Geri Hudson Cunliffe (1999-2001) |
| •Julie Peasgood | played | Jacqui Hudson (2000-2001) |
| •Paul Danan | played | Sol Patrick (1997-2001) |
| •Daniel Pape | played | Sean Tate (1997-1999, 2000) |
| •Kerrie Taylor | played | Lucy Benson (1995-2000) |
| •Lynda Rooke | played | Jill Patrick Osborne (1997-2000) |
| •Natalie Casey | played | Carol Groves (1995-2000) |
| •Natasha Symms | played | Kate Patrick (1997-1999, 2000) |
| •Tim Downie | played | Sam Smallwood (1999-2000) |
| •Warren Derosa | played | Rob Hawthorn (1995-2000) |
| •Wendy Glenn | played | Nikki Sullivan (1999-2000) |
| •Zander Ward | played | Paul Millington (1999-2000) |
| •James McKenzie Robinson | played | Joe Johnson (1998-1999) |
| •Jeremy Edwards | played | Kurt Benson (1995-1999) |
| •Liz Stooke | played | Angela Cunningham (1995-1999) |
| •Robert Weatherby | played | Kevin Daniels (1995-1999) |
| •Davina Taylor | played | Jude Cunningham (1997-1998) |
| •James Quinn (1) | played | Kirk Benson (1995-1998) |
| •Martine Brown (1) | played | Juliet Benson (1995-1998) |
| •Will Mellor (1) | played | Jambo Bolton (1995-1998) |
| •Lisa Williamson | played | Dawn Cunningham (1995-1997) |
| •Paul Leyshon | played | Ollie Benson (1995-1997) |
| •Yasmin Bannerman | played | Maddie Parker (1995-1997) |
| •Brett O'Brien | played | Louise Taylor (1995-1996) |
| •Alvin Stardust | played | Greg Anderson (1995) |
| •Benjamin Hart | played | Foz |
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