A retrospective on eight years of House.
Songs: Champion Jack Dupree -- Junker's Blues, Drew Holcomb & The Neighbours -- Live Forever, (Unknown artist) -- James Bond Theme from "Dr. No", (Unknown artist) -- The Glory of Love, (Unknown artist) -- The Tennessee Waltz
House has spent a year in prison after crushing through Cuddy's living room window. Now to win his parole, House has to behave for just five more days. However, an ailing prisoner pits House and his diagnosis against the hospital doctor, and his only ally is a young doctor who believes there's more to why he's in prison then he'll tell her.
House returns to Princeton Plainsboro on parole to provide his expertise on a unique case: a pair of donor lungs that are suffering a mysterious ailment. However, House soon finds himself hobbled when he learns that his old team has been let go, Wilson bears him a grudge, his new team member has personal problems, and if he crosses the new Dean of Medicine then he'll be sent back to prison.
Songs: Celine Dion
-- My Heart Will Go On, Fink
-- Yesterday Was Hard on All of Us
Benjamin, a wealthy man intent on giving away his money to charitable causes, collapses on the street. House doesn't believe there's anything seriously wrong with him, but treats him so that he can convince Benjamin that he's "cured" and to donate money to fund House's diagnostic team. However, when Benjamin starts showing serious symptoms, House realizes that he has a real illness on his hands. Meanwhile, Thirteen must decide whether to return to the hospital or go to Greece with her girlfriend, and new volunteer team member Dr. Adams tries to determine why Park won't take a gift.
Songs: The Wellspring -- The Ballad of el Goodo
House takes on the case of Thad Barton, a CEO relocating his employees to China who is suffering from vision problems. As Thad gets progressively worse, House engages in insider training with the company's stock so he can finance his department and bring Chase and Taub back. Meanwhile, Park makes the mistake of betting House that she won't get fired at her disciplinary hearing, and Adams has anger issues that puzzle and intrigue House.
A well-respected community leader has a heart attack while secretly having an affair. However, when his condition worsens, the man decides to confess all of his sins to the community, endangering his chances of getting a necessary liver transplant. Meanwhile, Taub and Chase return and House insists on knowing the paternity of Taub's two daughters.
Songs: Whiting, Egan & Kahn -- Ain't We Got Fun
House and his team take on the case of Ben, a teenager who aspires to be a circus clown like his biological father, who died years ago. When Ben becomes ill, the team need to find a compatible bone marrow donor and learn a dark secret about the family. Meanwhile, Taub ponders fatherhood when his wife wants to move to Portland with their daughter, and House tries to bypass his ankle monitor and go to a boxing match in Atlantic City with Wilson.
A 14-year-old girl suffers from an allergic reaction at her birthday party, but House is more interested in solving the death of a 4-year-old boy several years previously, despite the fact that he has to violate his parole to do so. Meanwhile, the team wonders why Chase has taken an interest in personal grooming.
The team treats a prosecutor suffering from what at first appears to be an anxiety attack. However, his symptoms soon grow worse and the man manifests extreme paranoia. While the doctors try to determine whether the paranoia is a symptom or not, Park grows paranoid about whether the others like her. Meanwhile, Wilson goes to extreme lengths to prove that House is paranoid enough to keep a gun, and Foreman believes Taub is trying to set him up on dates.
A man suffering from Alzheimer's coughs up blood and flies into violent rages. While the team tries to diagnose him, House tests Foreman's limits, and Wilson takes the case of a woman who claims that she and her boyfriend have an asexual relationship.
Songs: Morgan Taylor Reid -- Simply Human
House and his team treat an underage runaway girl who refuses to identify her parents, and House takes a personal interest in the case. Meanwhile, Taub tries to find common ground with his infant daughters, Foreman's affair takes a surprising turn, and House treats two brothers who engage in Civil War reenactments.
Songs: Foy Vance -- Be the Song
When a team member is injured while treating a patient, Foreman brings in his old mentor Dr. Cofield to get to the truth. However, it soon becomes clear that someone is at blame... even though the team insists that nobody is to blame.
To cope with his near-death experience, Chase seeks out an emotional bond with a nun preparing to take her vows, who is in the hospital with a life-threatening disease. Meanwhile, Taub tries to cope by learning self-defense, and House puts Taub's newly acquired skills to the test.
Songs: Ben Howard -- Promise
While House tests his team by declaring that one of them will be his new second, they treat a marriage coach who suffers from fever, uncontrollable self-urination and double-vision. It turns out that low testosterone levels are the cause, but the patient worries that the treatment may change him into a man that his wife doesn't want.
House and his team treat a blind man suffering from auditory hallucinations, but his condition soon worsens. Meanwhile, Blythe House arrives in town with news for her son.
The team treats an Army PFC suffering from abdominal pains, who leaked a video of a botched military operation to the Internet and is awaiting a court marital. His condition gets progressively worse but he refuses treatment until the Army provides him with the files that will prove how his father, a military officer, really died. Meanwhile, the team comes to believe that House has a liver condition that will result in his death, but he refuses to accept their diagnosis.
A 22-year-old minor league hockey player collapses on the ice, coughing up blood. While the team tries to diagnosis his condition, Chase offers to let Park move in with him and House gives Wilson some mixed news.
Songs: Lee Dorsey
-- Everything I Do Gonh Be Funky, Lionel Richie. -- Hello
House and his team handle the case of a man who cries blood, and discover that he has a unique ladyfriend who may be contributing to his health issues. Meanwhile, House auditions new hookers when his old one gives up the business for a husband. However, when he discovers he can't do without, House recruits Dominika to help ruin the relationship.
House's team treat a boy who is apparently possessed by demons, and they must deal with the mother's slowly developing belief that faith rather than science holds the answer to her son's cure. Meanwhile, Park and Chase have sex dreams about each other, and House lies to Dominika to keep her with him.
-- Black Moon
When House takes some vacation time to be with Wilson, the team must go on without him and handle the case of a six-year-old girl suffering from a genetic mutation which may or may not account or her current symptoms. Further complicating the situation is the fact that the girl's mother is a doctor and insists on treating her daughter. Meanwhile, House helps Wilson... whether his friend wants his help or not.
-- Any Way You Want It
While the team takes on the case of a resident pathologist who refuses treatment from anyone except House, House and Wilson go on a road trip to Cleveland to see Julie Christie. Meanwhile, Chase wonders if he should stay or go.
The team tries to deal with a patient, Derrick, who suffers from nosebleeds, dizziness, and the voice of his dead brother in his head. However, Park, Adams, and Taub are on their own after Chase resigns and House spends his time trying to convince Wilson to undergo chemotherapy to stay alive as long as possible despite the cancer eating away at him.
Songs: Motopony -- Euphoria
In the series finale, House treats a heroin-addicted patient whose outlook on life puts House in a burning building haunted by the ghosts of his past.