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House sympathizes with a 10-year-old autistic boy who screams loudly for no reason, but his co-workers soon wonder if House empathizes with the boy because he has no social graces either. Meanwhile, House spars with Cuddy over the remodeling of his office, and deals with a teenage crush.
Dr. House: (to Dr. Cuddy about Ali) You can't stop our love!!
Ali: What about us?
Dr. House: We'll always have Fresno . . .