An office building collapses and House must race against the clock to diagnose Megan, a young woman who survived the disaster but can only communicate through blinking. However, House is without a team after Foreman and Cameron quit and the firing of Chase, so he's forced to talk through his ideas with the hospital janitor. But when Megan's condition worsens, House is pressured to hire a new team. Though reluctant to do so, House begins to realize diagnosing patients by himself is not as easy as he thought.