Organophosphate poisoning
The culprit in this episode was an organophosphate. Many of these compounds are toxic. They are used as insecticides, herbicides and nerve gases (the famous Sarin nerve gases are this sort of chemical). They work by inhibiting acetylcholinesterase. This enzyme breaks down the neurotransmitter acetylcholine. Breaking this metabolic path prevents the neuron that is sensitive to the transmitter (called a cholinergic neuron) from returning to a resting state. This inhibits nerve impulse transmission and causes paralysis and eventually cell death. Many of these insecticides can be absorbed directly through the skin; organophosphate poisoning is an ongoing problem in rural areas.

Dr. Foreman: The kid was just taking his AP calculus exam when all of a sudden he got nauseous and disoriented.
Dr. House: That's the way calculus presents.

Dr. House: I want you to go to his house and find his stash. I'll bet you know all the good hiding spots.
Dr. Foreman: Actually, I never did drugs.
Dr. House: (to Cameron) Better go with him. In case he gets high.

Dr. Foreman: You know why House thinks I'm a druggie?
Dr. Cameron: This is going to be a racial thing, isn't it?

Dr. Cameron: You really never did any drugs?
Dr. Foreman: Now this is gonna be a racial thing.
Dr. Cameron: Deflecting a personal question with a joke. Gee, who do I know that does that?
Dr. Foreman: Yeah, I’m just like him. Except for the angry, bitter, pompous, cripple part.
Dr. Cameron: Maybe we should all pitch in and get you a nice cane. You already have the matching gym shoes.

Georgia Adams: I notice colors more. And music. I...I'm really hearing music. I'm eighty-two, and I'm supposed to be playing canasta with the other old ladies, but…now when I see a guy with a cute butt... I just can't stop looking at him. (ogles House) Or a sexy beard.
Dr. House: And you figure that enjoying cute butts is a sign of disease?

Georgia Adams: And now...I think about Ashton (Kutcher) all the time. (whispers) All the time.
Dr. House: Ah.
Georgia Adams: You remind me of him. Same bedroom eyes.
Dr. House: People are always mixing us up.

Dr. House: I assume "minimal at best" is your stiff upper lip British way of saying "no chance in hell"?
Dr. Chase: I'm Australian.
Dr. House: You put the Queen on your money. You're British.

Dr. Cameron: Are there any stronger treatments for the organophosphate poisoning?
Dr. House: Oh, damn it, you caught me. We went with the weak stuff. Just trying to save a little money.

Dr. Cameron: I'll check into it.
Dr. Foreman: I'll make the call.
Dr. Chase: I'll keep the kid alive. For a while at least.
Dr. House: I'll have lunch.

Dr. Wilson: (quoting Georgia's poem) "The healer with his magic powers! / I could rub his gentle brow for hours. / His manly chest, his stubbled jaw, / Everything about him leave me raw..."
Dr. House: Psych ward's upstairs
Dr. Wilson: "...with joy. Oh, House, your very name / Will never leave this girl the same." It's not bad for an 82-year-old. She asked me to give that to her true love.
Dr. House: What can I say? Chicks with no teeth turn me on.
Dr. Wilson: That's fairly disgusting.
Dr. House: And that's ageism.
Dr. Wilson: You better watch yourself around this babe.

Dr. Cuddy: (to House) Her only sign of mental illness is that she disagrees with you. Some would consider that a sign of sanity.

Margo Davis: Who are you?
Dr. House: I'm the doctor who's trying to save your son. You're the mom who's letting him die. Clarification-–it's a beautiful thing.

Dr. House: Would you step outside for a minute, Mr. Adams?
Mark Adams: Why?
Dr. House: Because you irritate me.

Dr. House: Well, you’re getting good at this God-like doctor racket. Why don’t you talk her out of this lunacy?
Dr. Foreman: She’s not really a big fan of mine.
Dr. Chase: Or mine.
Dr. House: Well, only one male left in the bullpen, and he throws like a girl.
Dr. Cameron: I hate sports metaphors.

Dr. House: I'm sorry--the fact that the sexual pleasure center of your cerebral cortex has been overstimulated by spirochetes is a poor basis for a relationship. I learned that one the hard way.

Dr. Wilson: Hey, I'm a man - I don't have time for laundry. I'm saving lives here!

Margo Davis: What makes you think you're right this time?
Dr. House: The same thing as last time.

Dr. House: Although there's a real good chance...
Margo Davis: What? Matt might kick off?
Dr. House: It's a little blunt. I was going to say "run out of time." Just kinda let my voice trail off...

Matt Davis: Who are those guys?
Margo Davis: Oh, they're the arrogant jerks that saved your life.

The students are seen taking the AP Calculus exam. Later, when Cameron is looking for poison in the garage, she is wearing a long coat and gloves. The problem is that the AP Calculus exam is only given (nationwide) in May which means it would be too warm to be wearing a coat and gloves in New Jersey at that time of year.

Dr. Wilson: Godot would be faster.

Wilson is referring to the title of Beckett's most famous work, Waiting for Godot. Beckett uses the characters' interaction to symbolise the tedium and meaninglessness of modern life, both major themes of the existentialists.