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House
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| Title: | Poison |
| Also Known As: | Tappavaa myrkkyä ( Finland)
Jed ( Czech Republic)
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| Episode Number: | 8 |
| Season: | 1 |
| Season Episode #.: | 8 |
| Production Number: | HOU-108 |
| Original Airdate: | Tuesday January 25th, 2005 |
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| | Other Release Dates: (Edit) | | Country: | Aired On: | |
| Finland |
Nov 09, 2006 |
| Czech Republic |
Nov 22, 2006 |
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A young high school male comes in to the hospital with a lethal poisoning, but neither House or the rest of his team can find out what has caused it. House decides to send Cameron and Chase to the teen's home to find the hot new drug House is sure he's taking. They don't find drugs, but do find something that would explain his symptoms. That is until another student comes in with the exact same symptoms. Meanwhile, an 82-year-old patient becomes obsessed with House who is trying to figure out the basis of her renewed fascination with her sexual feelings.
| There are no foreign summaries for this episode
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| This episode has a parental advisory: "Due to the graphic nature of this program, viewer discretion is advised." before the teaser.
| Organophosphate poisoning
The culprit in this episode was an organophosphate. Many of these compounds are toxic. They are used as insecticides, herbicides and nerve gases (the famous Sarin nerve gases are this sort of chemical). They work by inhibiting acetylcholinesterase. This enzyme breaks down the neurotransmitter acetylcholine. Breaking this metabolic path prevents the neuron that is sensitive to the transmitter (called a cholinergic neuron) from returning to a resting state. This inhibits nerve impulse transmission and causes paralysis and eventually cell death. Many of these insecticides can be absorbed directly through the skin; organophosphate poisoning is an ongoing problem in rural areas.
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| Matt: Who are those guys?
Margo: Oh, they're the arrogant jerks that saved your life.
| Dr. Foreman: You know why House thinks I'm a druggie?
Dr. Cameron: This is going to be a racial thing, isn't it?
| Georgia: And now...I think about Ashton (Kutcher) all the time. (whispers) All the time.
House: Ah.
Georgia: You remind me of him. Same bedroom eyes.
House: People are always mixing us up.
| House: I assume "minimal at best" is your stiff upper lip British way of saying "no chance in hell"?
Dr. Chase: I'm Australian.
House: You put the Queen on your money. You're British.
| Dr. Cameron: I'll check into it.
Dr. Foreman: I'll make the call.
Dr. Chase: I'll keep the kid alive. For a while at least.
House: I'll have lunch.
| Dr. Wilson: Hey, I'm a man - I don't have time for laundry. I'm saving lives here!
| House: Would you step outside for a minute, Mr. Adams?
Matt: Why?
House: Because you irritate me.
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| The students are seen taking the AP Calculus exam. Later, when Cameron is looking for poison in the garage, she is wearing a long coat and gloves. The problem is that the AP Calculus exam is only given (nationwide) in May which means it would be too warm to be wearing a coat and gloves in New Jersey at that time of year.
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| Dr. Wilson: Godot would be faster.
Wilson is referring to the title of Beckett's most famous work, "Waiting for Godot." Beckett uses the characters' interaction to symbolise the tedium and meaninglessness of modern life, both major themes of the existentialists.
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