The four run into each other at a Los Angeles hospital, where Jason is treated for a self-inflicted gunshot wound. Meanwhile, Sherman is arrested for hijacking a bakery truck after his wife leaves him and cleans him out.
Kelly's crazed cop boyfriend, Frank, catches Harry helping her move her things out of his place. Meanwhile Sherman's staff refuses to help him as his professional reputation spirals down, and Jason, now seriously smitten with Dr. Joanna, doggedly pursues her at the hospital.
Sherman and Harry sneak into an ashram to retrieve Sherman's ex-wife, who currently lives with a phony billionaire guru. Kelly confesses to Harry that she accidentally killed her husband during a golf game. And Jason tries to convince Dr. Joanna's grandmother to accept medical treatment to save her life.
Jason dodges a process server; when Harry's boss chastises him, he quits his job; and Sherman wears a disguise to avoid hostile fellow shoppers at a supermarket.
Harry begs Kelly not to tell Sherman and Jason that she's a hooker, while Sherman discovers that Jason's investment company has lost all of his money, and Dr. Joanna rejects Jason's advances.
Jason, on the verge of going to jail, can cut a deal if he rats on his Uncle Henry, who happens to be his mother Donna's favorite brother. Jason begs Harry to help him with his mother because she always favored Harry over him. Things quickly get hot when Donna's flirting with Harry leads to a deep, passionate kiss, leaving Harry more than a little flustered. And Kelly takes Sherman to a strip club in an attempt to get him over his wife.
Jason is furious to discover that his mother, Donna, is having an affair with Harry, forcing him to rethink his love for Joanna. Meanwhile Sherman struggles to maintain his diet, and Dylan develops a crush on Kelly.
Sherman convinces Kelly to help him kidnap his wife from an Ashram. Meanwhile, Harry reveals to Jason he's having sex with Jason's mother, and Jason has proof that Dr. Joanna kissed him.
A surprise visit by Kelly's strict parents causes her to create a new life for herself, with help from Harry, who is prepared to be her husband. But then Kelly ends up choosing Jason. Things get really interesting, however, when her parents demand that she have a traditional Korean wedding.
When Harry's son, Dylan, is repeatedly harassed by a school bully, Kelly ignores Harry's passive solution by hiring two goons from the massage parlor to protect Dylan at school. And when Jason finally gets Dr. Joanna to go out with him, he finds himself mortified as all his possessions get repossessed right in front of her.
Harry and Sherman go to a spa to escape women, but Sherman spends the vacation looking for women. Meanwhile, Joanna gets a pain in her neck whenever Jason's name is mentioned, so she goes to see Kelly for a massage.
Harry tries to get his ex-wife and her boyfriend to marry so he can stop paying alimony. However he suddenly feels left out when his son prefers this new man over him. Meanwhile, Jason realizes his lawyer is Joanna's fiancé, and Sherman tries to extend his fading fame by going into rehab.
Harry and Maureen try their hand at getting back together. Meanshile Joanna discovers a hidden attachment to Jason, and Shermans book goes #1 in Japan -- making him a celebrity again.